SK39498A3 - Synthetic multivalent slex containing polylactosamines and methods for use - Google Patents

Synthetic multivalent slex containing polylactosamines and methods for use Download PDF

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Publication number
SK39498A3
SK39498A3 SK394-98A SK39498A SK39498A3 SK 39498 A3 SK39498 A3 SK 39498A3 SK 39498 A SK39498 A SK 39498A SK 39498 A3 SK39498 A3 SK 39498A3
Authority
SK
Slovakia
Prior art keywords
patient
selectin
slex
glycan
glcnac
Prior art date
Application number
SK394-98A
Other languages
English (en)
Slovak (sk)
Inventor
Ossi Renkonen
Risto Renkonen
Original Assignee
Glycim Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycim Oy filed Critical Glycim Oy
Publication of SK39498A3 publication Critical patent/SK39498A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SK394-98A 1995-09-29 1996-09-27 Synthetic multivalent slex containing polylactosamines and methods for use SK39498A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US462395P 1995-09-29 1995-09-29
US786795P 1995-12-01 1995-12-01
PCT/FI1996/000513 WO1997012892A1 (fr) 1995-09-29 1996-09-27 sLEX SYNTHETIQUE POLYVALENT CONTENANT DES POLYLACTOSAMINES ET PROCEDES D'UTILISATION

Publications (1)

Publication Number Publication Date
SK39498A3 true SK39498A3 (en) 1999-01-11

Family

ID=26673254

Family Applications (1)

Application Number Title Priority Date Filing Date
SK394-98A SK39498A3 (en) 1995-09-29 1996-09-27 Synthetic multivalent slex containing polylactosamines and methods for use

Country Status (11)

Country Link
US (1) US5965544A (fr)
EP (1) EP0874861A1 (fr)
JP (1) JP2000507993A (fr)
AU (1) AU713078B2 (fr)
CA (1) CA2231073A1 (fr)
CZ (1) CZ89098A3 (fr)
HU (1) HUP9900058A2 (fr)
NO (1) NO981361L (fr)
PL (1) PL325873A1 (fr)
SK (1) SK39498A3 (fr)
WO (1) WO1997012892A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204431B1 (en) 1994-03-09 2001-03-20 Abbott Laboratories Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk
US6841543B1 (en) * 1996-01-31 2005-01-11 President And Fellows Of Harvard College Methods of inhibiting production of T helper type 2 cytokines in human immune cells
JP4179567B2 (ja) * 1996-07-23 2008-11-12 生化学工業株式会社 新規ラクトサミンオリゴ糖およびその製造方法
JP2001515912A (ja) 1997-09-05 2001-09-25 グリシム オサケ ユキチュア 合成二価ｓＬｅｘ含有ポリラクトサミン類および使用法
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
SE9904581D0 (sv) * 1999-12-15 1999-12-15 A & Science Invest Ab A novel helicobacter pylori-binding substance and use thereof
AU2001261534A1 (en) * 2000-05-11 2001-11-20 The Burnham Institute The meca-79 antigen and related methods
DE60139720D1 (de) * 2000-06-28 2009-10-08 Glycofi Inc Verfahren für die Herstellung modifizierter Glykoproteine
AU2001287422A1 (en) * 2000-08-22 2002-03-04 National Research Council Of Canada Synthesis of complex carbohydrates
US20050026866A1 (en) * 2002-08-02 2005-02-03 Pawelek John M. Agents and methods for treatment of disease by oligosaccharide targeting agents

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
WO1991019501A1 (fr) * 1990-06-15 1991-12-26 Cytel Corporation Mediateurs d'adherence intercellulaire
US5211937A (en) * 1990-07-30 1993-05-18 Glycomed Incorporated Method of determining a site of inflammation utilizing elam-1 ligands
US5352670A (en) * 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
CA2110797C (fr) * 1991-06-10 2001-02-20 Andre P. Venot Composes lewis x sialyliques modifies
CA2129140A1 (fr) * 1992-01-31 1993-08-05 Akira Hasegawa Derive d'une chaine de sucre de type lewis
JPH0686684A (ja) * 1992-05-26 1994-03-29 Monsanto Co シアロ抱合体の合成
US5591835A (en) * 1992-06-29 1997-01-07 Glycomed Incorporated Substituted lactose derivatives
US5426178A (en) * 1993-03-31 1995-06-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis of anti-inflammatory compounds, and novel trisaccharides useful in the synthesis of anti-inflammatory compounds
JPH08509720A (ja) * 1993-05-03 1996-10-15 ジェネンテク、インコーポレイテッド 白血球接着阻害
US5374541A (en) * 1993-05-04 1994-12-20 The Scripps Research Institute Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
US5409817A (en) * 1993-05-04 1995-04-25 Cytel, Inc. Use of trans-sialidase and sialyltransferase for synthesis of sialylα2→3βgalactosides
CN1125449A (zh) * 1993-05-14 1996-06-26 萨依特尔有限公司 作为细胞粘附抑制剂的唾液基Lex类似物
WO1995001361A1 (fr) * 1993-07-02 1995-01-12 Nippon Shinyaku Co., Ltd. Derive de galactosylmoranoline
US5559103A (en) * 1993-07-21 1996-09-24 Cytel Corporation Bivalent sialyl X saccharides
AU7467394A (en) * 1993-08-23 1995-03-21 Nippon Shinyaku Co. Ltd. Galactosylmoranoline derivative
EP0671409A3 (fr) * 1994-03-11 1996-06-12 Hoechst Ag Dérivés de l'acide malonique ayant des propriétés anti-adhésives.
HUT77345A (hu) * 1994-04-29 1998-03-30 Texas Biotechnology Corporation E-szelektin, P-szelektin vagy L-szelektin szialil-Lewis x-hez vagy szialil-Lewis a-hoz kapcsolódását gátló mannopiranoziloxi-bifenil származékok és ezeket tartalmazó gyógyszerkészítmények

Also Published As

Publication number Publication date
CZ89098A3 (cs) 1998-09-16
EP0874861A1 (fr) 1998-11-04
US5965544A (en) 1999-10-12
AU7087296A (en) 1997-04-28
NO981361L (no) 1998-05-26
WO1997012892A1 (fr) 1997-04-10
NO981361D0 (no) 1998-03-25
AU713078B2 (en) 1999-11-25
PL325873A1 (en) 1998-08-17
JP2000507993A (ja) 2000-06-27
CA2231073A1 (fr) 1997-04-10
HUP9900058A2 (hu) 1999-04-28

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