SK298692A3 - Etoposide-4'-phosphoric acid crystalline diethanolate and method for preparing same - Google Patents

Etoposide-4'-phosphoric acid crystalline diethanolate and method for preparing same Download PDF

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Publication number
SK298692A3
SK298692A3 SK2986-92A SK298692A SK298692A3 SK 298692 A3 SK298692 A3 SK 298692A3 SK 298692 A SK298692 A SK 298692A SK 298692 A3 SK298692 A3 SK 298692A3
Authority
SK
Slovakia
Prior art keywords
etoposide
phosphoric acid
diethanolate
crystalline
solution
Prior art date
Application number
SK2986-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK278935B6 (sk
Inventor
Denis Favreau
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of SK278935B6 publication Critical patent/SK278935B6/sk
Publication of SK298692A3 publication Critical patent/SK298692A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
SK2986-92A 1991-10-08 1992-09-30 Etoposide-4'-phosphoric acid crystalline diethanolate and method for preparing same SK298692A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/773,056 US5648474A (en) 1991-10-08 1991-10-08 Crystalline etoposide 4'-phosphate diethanolate

Publications (2)

Publication Number Publication Date
SK278935B6 SK278935B6 (sk) 1998-04-08
SK298692A3 true SK298692A3 (en) 1998-04-08

Family

ID=25097069

Family Applications (1)

Application Number Title Priority Date Filing Date
SK2986-92A SK298692A3 (en) 1991-10-08 1992-09-30 Etoposide-4'-phosphoric acid crystalline diethanolate and method for preparing same

Country Status (27)

Country Link
US (1) US5648474A (pl)
EP (1) EP0537555B1 (pl)
JP (1) JP3205816B2 (pl)
KR (1) KR100243981B1 (pl)
CN (1) CN1030610C (pl)
AT (1) ATE156832T1 (pl)
AU (1) AU650572B2 (pl)
CA (1) CA2079581C (pl)
CZ (1) CZ283735B6 (pl)
DE (1) DE69221573T2 (pl)
DK (1) DK0537555T3 (pl)
EG (1) EG20187A (pl)
ES (1) ES2109970T3 (pl)
FI (1) FI105034B (pl)
GR (1) GR3025176T3 (pl)
HU (2) HU213606B (pl)
IL (1) IL103262A (pl)
MX (1) MX9205777A (pl)
MY (1) MY108969A (pl)
NO (1) NO178342C (pl)
NZ (1) NZ244521A (pl)
PH (1) PH31666A (pl)
PL (1) PL168332B1 (pl)
RU (1) RU2042686C1 (pl)
SK (1) SK298692A3 (pl)
TW (1) TW239863B (pl)
ZA (1) ZA926903B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914222A (en) * 1983-08-29 1990-04-03 Merck & Co., Inc. Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
US4670578A (en) * 1983-08-29 1987-06-02 Merck & Co., Inc. Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
US4713246A (en) * 1984-03-19 1987-12-15 Bristol-Myers Company Etoposide oral dosage form
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4927638A (en) * 1986-10-08 1990-05-22 Bristol-Myers Company Etoposide solutions
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
DE68912721T2 (de) * 1988-11-16 1994-05-11 Nippon Kayaku Kk Kristallines Hydrochlorid von einer Etoposid-2-dimethylamino-Verbindung und Verfahren zur Herstellung davon.
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides

Also Published As

Publication number Publication date
DK0537555T3 (da) 1998-01-26
HU211672A9 (en) 1995-12-28
ES2109970T3 (es) 1998-02-01
NO178342C (no) 1996-03-06
SK278935B6 (sk) 1998-04-08
IL103262A (en) 1997-06-10
MX9205777A (es) 1993-04-01
NO923754L (no) 1993-04-13
CA2079581A1 (en) 1993-04-09
KR100243981B1 (ko) 2000-02-01
KR930007968A (ko) 1993-05-20
DE69221573D1 (de) 1997-09-18
TW239863B (pl) 1995-02-01
EP0537555A1 (en) 1993-04-21
JP3205816B2 (ja) 2001-09-04
US5648474A (en) 1997-07-15
EP0537555B1 (en) 1997-08-13
CA2079581C (en) 2002-11-12
AU2530192A (en) 1993-04-22
CN1071432A (zh) 1993-04-28
PL296078A1 (en) 1993-04-19
AU650572B2 (en) 1994-06-23
HU213606B (en) 1997-08-28
HUT62309A (en) 1993-04-28
PL168332B1 (pl) 1996-02-29
FI924359A0 (fi) 1992-09-29
CN1030610C (zh) 1996-01-03
ATE156832T1 (de) 1997-08-15
EG20187A (en) 1997-09-30
MY108969A (en) 1996-11-30
PH31666A (en) 1999-01-12
CZ298692A3 (en) 1993-04-14
FI105034B (fi) 2000-05-31
HU9203119D0 (en) 1992-12-28
GR3025176T3 (en) 1998-02-27
DE69221573T2 (de) 1998-02-26
NO178342B (no) 1995-11-27
NZ244521A (en) 1994-02-25
ZA926903B (en) 1993-05-03
NO923754D0 (no) 1992-09-28
FI924359A (fi) 1993-04-09
RU2042686C1 (ru) 1995-08-27
IL103262A0 (en) 1993-02-21
CZ283735B6 (cs) 1998-06-17
JPH05194575A (ja) 1993-08-03

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Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20120930