FI105034B - Kiteinen etoposidi-4'-fosfaattidietanolaatti - Google Patents

Kiteinen etoposidi-4'-fosfaattidietanolaatti Download PDF

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Publication number
FI105034B
FI105034B FI924359A FI924359A FI105034B FI 105034 B FI105034 B FI 105034B FI 924359 A FI924359 A FI 924359A FI 924359 A FI924359 A FI 924359A FI 105034 B FI105034 B FI 105034B
Authority
FI
Finland
Prior art keywords
etoposide
phosphate
solution
crystalline
diethanolate
Prior art date
Application number
FI924359A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI924359A0 (fi
FI924359A (fi
Inventor
Denis Favreau
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of FI924359A0 publication Critical patent/FI924359A0/fi
Publication of FI924359A publication Critical patent/FI924359A/fi
Application granted granted Critical
Publication of FI105034B publication Critical patent/FI105034B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
FI924359A 1991-10-08 1992-09-29 Kiteinen etoposidi-4'-fosfaattidietanolaatti FI105034B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77305691 1991-10-08
US07/773,056 US5648474A (en) 1991-10-08 1991-10-08 Crystalline etoposide 4'-phosphate diethanolate

Publications (3)

Publication Number Publication Date
FI924359A0 FI924359A0 (fi) 1992-09-29
FI924359A FI924359A (fi) 1993-04-09
FI105034B true FI105034B (fi) 2000-05-31

Family

ID=25097069

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924359A FI105034B (fi) 1991-10-08 1992-09-29 Kiteinen etoposidi-4'-fosfaattidietanolaatti

Country Status (27)

Country Link
US (1) US5648474A (pl)
EP (1) EP0537555B1 (pl)
JP (1) JP3205816B2 (pl)
KR (1) KR100243981B1 (pl)
CN (1) CN1030610C (pl)
AT (1) ATE156832T1 (pl)
AU (1) AU650572B2 (pl)
CA (1) CA2079581C (pl)
CZ (1) CZ283735B6 (pl)
DE (1) DE69221573T2 (pl)
DK (1) DK0537555T3 (pl)
EG (1) EG20187A (pl)
ES (1) ES2109970T3 (pl)
FI (1) FI105034B (pl)
GR (1) GR3025176T3 (pl)
HU (2) HU213606B (pl)
IL (1) IL103262A (pl)
MX (1) MX9205777A (pl)
MY (1) MY108969A (pl)
NO (1) NO178342C (pl)
NZ (1) NZ244521A (pl)
PH (1) PH31666A (pl)
PL (1) PL168332B1 (pl)
RU (1) RU2042686C1 (pl)
SK (1) SK298692A3 (pl)
TW (1) TW239863B (pl)
ZA (1) ZA926903B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914222A (en) * 1983-08-29 1990-04-03 Merck & Co., Inc. Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
US4670578A (en) * 1983-08-29 1987-06-02 Merck & Co., Inc. Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
US4713246A (en) * 1984-03-19 1987-12-15 Bristol-Myers Company Etoposide oral dosage form
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4927638A (en) * 1986-10-08 1990-05-22 Bristol-Myers Company Etoposide solutions
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
ES2061891T3 (es) * 1988-11-16 1994-12-16 Nippon Kayaku Kk Cristales de dihidrato de dihidrocloruro de compuesto de etoposido-2-dimetilamina y un procedimiento para su produccion.
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides

Also Published As

Publication number Publication date
IL103262A0 (en) 1993-02-21
CZ298692A3 (en) 1993-04-14
HU9203119D0 (en) 1992-12-28
CN1071432A (zh) 1993-04-28
HUT62309A (en) 1993-04-28
DE69221573D1 (de) 1997-09-18
NO178342B (no) 1995-11-27
GR3025176T3 (en) 1998-02-27
EP0537555B1 (en) 1997-08-13
FI924359A0 (fi) 1992-09-29
JP3205816B2 (ja) 2001-09-04
KR930007968A (ko) 1993-05-20
IL103262A (en) 1997-06-10
RU2042686C1 (ru) 1995-08-27
CA2079581C (en) 2002-11-12
AU2530192A (en) 1993-04-22
ES2109970T3 (es) 1998-02-01
MX9205777A (es) 1993-04-01
CN1030610C (zh) 1996-01-03
NO923754L (no) 1993-04-13
HU213606B (en) 1997-08-28
JPH05194575A (ja) 1993-08-03
FI924359A (fi) 1993-04-09
ATE156832T1 (de) 1997-08-15
PL168332B1 (pl) 1996-02-29
SK278935B6 (sk) 1998-04-08
NZ244521A (en) 1994-02-25
PH31666A (en) 1999-01-12
DE69221573T2 (de) 1998-02-26
EG20187A (en) 1997-09-30
NO923754D0 (no) 1992-09-28
DK0537555T3 (da) 1998-01-26
HU211672A9 (en) 1995-12-28
KR100243981B1 (ko) 2000-02-01
US5648474A (en) 1997-07-15
MY108969A (en) 1996-11-30
AU650572B2 (en) 1994-06-23
TW239863B (pl) 1995-02-01
SK298692A3 (en) 1998-04-08
NO178342C (no) 1996-03-06
CA2079581A1 (en) 1993-04-09
PL296078A1 (en) 1993-04-19
CZ283735B6 (cs) 1998-06-17
ZA926903B (en) 1993-05-03
EP0537555A1 (en) 1993-04-21

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