SK287248B6 - Pyrol[2,1-b][1,3]benzotiazepíny a ich použitie na prípravu liečiv s antipsychotickou aktivitou - Google Patents
Pyrol[2,1-b][1,3]benzotiazepíny a ich použitie na prípravu liečiv s antipsychotickou aktivitou Download PDFInfo
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- SK287248B6 SK287248B6 SK130-2003A SK1302003A SK287248B6 SK 287248 B6 SK287248 B6 SK 287248B6 SK 1302003 A SK1302003 A SK 1302003A SK 287248 B6 SK287248 B6 SK 287248B6
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- Slovakia
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- compounds according
- medicament
- pyrrolo
- alkyl
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- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical class O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 230000000862 serotonergic effect Effects 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 229950001675 spiperone Drugs 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 230000015883 synaptic transmission, dopaminergic Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 description 1
- 150000008648 triflates Chemical class 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000RM000432A IT1317884B1 (it) | 2000-08-01 | 2000-08-01 | Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica. |
| PCT/IT2001/000406 WO2002010175A1 (en) | 2000-08-01 | 2001-07-26 | PYRROLO[2,1-b][1,3]BENZOTHIAZEPINES AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS WITH ANTIPSYCHOTIC ACTIVITY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK1302003A3 SK1302003A3 (en) | 2003-05-02 |
| SK287248B6 true SK287248B6 (sk) | 2010-04-07 |
Family
ID=11454865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK130-2003A SK287248B6 (sk) | 2000-08-01 | 2001-07-26 | Pyrol[2,1-b][1,3]benzotiazepíny a ich použitie na prípravu liečiv s antipsychotickou aktivitou |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6710041B2 (pt) |
| EP (1) | EP1307463B1 (pt) |
| JP (1) | JP2004505090A (pt) |
| KR (1) | KR100826304B1 (pt) |
| CN (1) | CN1264848C (pt) |
| AT (1) | ATE287890T1 (pt) |
| AU (2) | AU8439101A (pt) |
| BR (1) | BR0112843A (pt) |
| CA (1) | CA2415475C (pt) |
| CZ (1) | CZ299340B6 (pt) |
| DE (1) | DE60108642T2 (pt) |
| DK (1) | DK1307463T3 (pt) |
| ES (1) | ES2236291T3 (pt) |
| HK (1) | HK1059774A1 (pt) |
| IT (1) | IT1317884B1 (pt) |
| MX (1) | MXPA03000775A (pt) |
| PL (1) | PL203096B1 (pt) |
| PT (1) | PT1307463E (pt) |
| SK (1) | SK287248B6 (pt) |
| WO (1) | WO2002010175A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20040178A1 (it) * | 2004-04-07 | 2004-07-07 | Sigma Tau Ind Farmaceuti | Composti ad attivita' antipsicotica atipica. |
| ITRM20040222A1 (it) * | 2004-05-07 | 2004-08-07 | Sigma Tau Ind Farmaceuti | Derivati dealchilati di pirrolo[2,1-b]benzotiazepine ad attivita' antipsicotica atipica. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1301965B1 (it) | 1998-07-28 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Pirrolo (2,1-b)(1,3) benzotiazepine con attivita' antipsicoticaatipica. |
-
2000
- 2000-08-01 IT IT2000RM000432A patent/IT1317884B1/it active
-
2001
- 2001-07-26 WO PCT/IT2001/000406 patent/WO2002010175A1/en active IP Right Grant
- 2001-07-26 JP JP2002515904A patent/JP2004505090A/ja not_active Withdrawn
- 2001-07-26 SK SK130-2003A patent/SK287248B6/sk not_active IP Right Cessation
- 2001-07-26 CA CA2415475A patent/CA2415475C/en not_active Expired - Fee Related
- 2001-07-26 KR KR1020037000934A patent/KR100826304B1/ko not_active IP Right Cessation
- 2001-07-26 US US10/343,627 patent/US6710041B2/en not_active Expired - Fee Related
- 2001-07-26 MX MXPA03000775A patent/MXPA03000775A/es active IP Right Grant
- 2001-07-26 EP EP01963371A patent/EP1307463B1/en not_active Expired - Lifetime
- 2001-07-26 PT PT01963371T patent/PT1307463E/pt unknown
- 2001-07-26 AU AU8439101A patent/AU8439101A/xx active Pending
- 2001-07-26 AU AU2001284391A patent/AU2001284391B2/en not_active Ceased
- 2001-07-26 DK DK01963371T patent/DK1307463T3/da active
- 2001-07-26 AT AT01963371T patent/ATE287890T1/de not_active IP Right Cessation
- 2001-07-26 DE DE60108642T patent/DE60108642T2/de not_active Expired - Lifetime
- 2001-07-26 ES ES01963371T patent/ES2236291T3/es not_active Expired - Lifetime
- 2001-07-26 BR BR0112843-4A patent/BR0112843A/pt not_active Application Discontinuation
- 2001-07-26 PL PL365008A patent/PL203096B1/pl not_active IP Right Cessation
- 2001-07-26 CN CNB018133886A patent/CN1264848C/zh not_active Expired - Fee Related
- 2001-07-26 CZ CZ20030012A patent/CZ299340B6/cs not_active IP Right Cessation
-
2004
- 2004-02-06 HK HK04100773A patent/HK1059774A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1264848C (zh) | 2006-07-19 |
| PT1307463E (pt) | 2005-04-29 |
| DK1307463T3 (da) | 2005-05-23 |
| KR100826304B1 (ko) | 2008-04-29 |
| ITRM20000432A0 (it) | 2000-08-01 |
| US6710041B2 (en) | 2004-03-23 |
| ATE287890T1 (de) | 2005-02-15 |
| HK1059774A1 (en) | 2004-07-16 |
| EP1307463A1 (en) | 2003-05-07 |
| CA2415475C (en) | 2010-09-28 |
| PL203096B1 (pl) | 2009-08-31 |
| ITRM20000432A1 (it) | 2002-02-01 |
| DE60108642T2 (de) | 2006-06-14 |
| AU2001284391B2 (en) | 2006-09-28 |
| SK1302003A3 (en) | 2003-05-02 |
| JP2004505090A (ja) | 2004-02-19 |
| CZ200312A3 (cs) | 2003-05-14 |
| IT1317884B1 (it) | 2003-07-15 |
| CN1444588A (zh) | 2003-09-24 |
| DE60108642D1 (de) | 2005-03-03 |
| KR20030019598A (ko) | 2003-03-06 |
| MXPA03000775A (es) | 2003-10-15 |
| BR0112843A (pt) | 2003-04-22 |
| ES2236291T3 (es) | 2005-07-16 |
| PL365008A1 (en) | 2004-12-27 |
| AU8439101A (en) | 2002-02-13 |
| WO2002010175A1 (en) | 2002-02-07 |
| CZ299340B6 (cs) | 2008-06-25 |
| EP1307463B1 (en) | 2005-01-26 |
| CA2415475A1 (en) | 2002-02-07 |
| US20030186959A1 (en) | 2003-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20110726 |