IT1317884B1 - Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica. - Google Patents

Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica.

Info

Publication number
IT1317884B1
IT1317884B1 IT2000RM000432A ITRM20000432A IT1317884B1 IT 1317884 B1 IT1317884 B1 IT 1317884B1 IT 2000RM000432 A IT2000RM000432 A IT 2000RM000432A IT RM20000432 A ITRM20000432 A IT RM20000432A IT 1317884 B1 IT1317884 B1 IT 1317884B1
Authority
IT
Italy
Prior art keywords
alkyl
pirrolo
benzothiazepine
preparation
classic antipsychotic
Prior art date
Application number
IT2000RM000432A
Other languages
English (en)
Inventor
Patrizia Minetti
Cesare Assunta Di
Domenico Mastroianni
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM20000432A0 publication Critical patent/ITRM20000432A0/it
Priority to IT2000RM000432A priority Critical patent/IT1317884B1/it
Priority to AU2001284391A priority patent/AU2001284391B2/en
Priority to CNB018133886A priority patent/CN1264848C/zh
Priority to AT01963371T priority patent/ATE287890T1/de
Priority to DK01963371T priority patent/DK1307463T3/da
Priority to KR1020037000934A priority patent/KR100826304B1/ko
Priority to US10/343,627 priority patent/US6710041B2/en
Priority to PCT/IT2001/000406 priority patent/WO2002010175A1/en
Priority to EP01963371A priority patent/EP1307463B1/en
Priority to DE60108642T priority patent/DE60108642T2/de
Priority to BR0112843-4A priority patent/BR0112843A/pt
Priority to PL365008A priority patent/PL203096B1/pl
Priority to CZ20030012A priority patent/CZ299340B6/cs
Priority to CA2415475A priority patent/CA2415475C/en
Priority to JP2002515904A priority patent/JP2004505090A/ja
Priority to ES01963371T priority patent/ES2236291T3/es
Priority to PT01963371T priority patent/PT1307463E/pt
Priority to SK130-2003A priority patent/SK287248B6/sk
Priority to AU8439101A priority patent/AU8439101A/xx
Priority to MXPA03000775A priority patent/MXPA03000775A/es
Priority to SI200130286T priority patent/SI1307463T1/xx
Publication of ITRM20000432A1 publication Critical patent/ITRM20000432A1/it
Application granted granted Critical
Publication of IT1317884B1 publication Critical patent/IT1317884B1/it
Priority to HK04100773A priority patent/HK1059774A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT2000RM000432A 2000-08-01 2000-08-01 Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica. IT1317884B1 (it)

Priority Applications (22)

Application Number Priority Date Filing Date Title
IT2000RM000432A IT1317884B1 (it) 2000-08-01 2000-08-01 Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica.
BR0112843-4A BR0112843A (pt) 2000-08-01 2001-07-26 Pirrolo[2,1-b][1,3]benzotiazepinas e seu uso para preparação de medicamentos com atividade antipsicótica
CZ20030012A CZ299340B6 (cs) 2000-08-01 2001-07-26 Pyrrolo[2,1-b][1,3]benzothiazepiny a jejich použití pro prípravu léciv s antipsychotickým pusobením
AT01963371T ATE287890T1 (de) 2000-08-01 2001-07-26 Pyrrolo 2,1-b)-(1,3)benzothiazepine ud ihre verwendung zur herstellung von medikamenten mit antipsychotischer aktivität
DK01963371T DK1307463T3 (da) 2000-08-01 2001-07-26 Pyrrolo[2,1-b][1,3]benzothiazepiner og deres anvendelse til fremstillingen af medikamenter med antipsykotisk aktivitet
KR1020037000934A KR100826304B1 (ko) 2000-08-01 2001-07-26 피롤로[2,1-ｂ][1,3]벤조티아제핀 및 정신병 치료 활성을갖는 약제의 제조를 위한 그의 용도
US10/343,627 US6710041B2 (en) 2000-08-01 2001-07-26 Pyrrolo[2,1-B][3,1] benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
PCT/IT2001/000406 WO2002010175A1 (en) 2000-08-01 2001-07-26 PYRROLO[2,1-b][1,3]BENZOTHIAZEPINES AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS WITH ANTIPSYCHOTIC ACTIVITY
EP01963371A EP1307463B1 (en) 2000-08-01 2001-07-26 Pyrrolo 2,1-b]-[1,3]benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
DE60108642T DE60108642T2 (de) 2000-08-01 2001-07-26 Pyrrolo 2,1-b]-[1,3]benzothiazepine ud ihre verwendung zur herstellung von medikamenten mit antipsychotischer aktivität
AU2001284391A AU2001284391B2 (en) 2000-08-01 2001-07-26 Pyrrolo[2,1-b][1,3]benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
PL365008A PL203096B1 (pl) 2000-08-01 2001-07-26 Pirolo [2,1-b] [1,3] benzotiazepiny, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie do wytwarzania leków o działaniu antypsychotycznym
CNB018133886A CN1264848C (zh) 2000-08-01 2001-07-26 吡咯并[2,1－b][1,3]苯并硫杂氮杂䓬类及其用于制备具有抗精神病活性药物的用途
CA2415475A CA2415475C (en) 2000-08-01 2001-07-26 Pyrrolo[2,1-b][1,3]benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
JP2002515904A JP2004505090A (ja) 2000-08-01 2001-07-26 ピロロ［２，１−ｂ］［１，３］ベンゾチアゼピンおよび抗精神病活性を有する薬剤の調製のためのその使用
ES01963371T ES2236291T3 (es) 2000-08-01 2001-07-26 Pirrolo(2,1-b)(1,3)benzotiazepinas y su uso para la preparacion de medicamentos con actividad antipsicotica.
PT01963371T PT1307463E (pt) 2000-08-01 2001-07-26 Pirrolo [2,1-b] [1,3] benzotiazepinas e sua utilizacao para a preparacao de medicamentos com actividade antipsicotica
SK130-2003A SK287248B6 (sk) 2000-08-01 2001-07-26 Pyrol[2,1-b][1,3]benzotiazepíny a ich použitie na prípravu liečiv s antipsychotickou aktivitou
AU8439101A AU8439101A (en) 2000-08-01 2001-07-26 Pyrrolo(2,1-b)(1,3)benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
MXPA03000775A MXPA03000775A (es) 2000-08-01 2001-07-26 Pirrol[2,1-b][1,3]benzotiazepinas y su suo para la preparacion de medicamentos con actividad antisicotica.
SI200130286T SI1307463T1 (en) 2000-08-01 2001-07-26 Pyrrolo 2,1-b)-(1,3)benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
HK04100773A HK1059774A1 (en) 2000-08-01 2004-02-06 Pyrrolo Ä2,1-BÜ Ä1,3Übenzothiazepines and their use for the preparation of medicaments with antipsychotic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000RM000432A IT1317884B1 (it) 2000-08-01 2000-08-01 Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica.

Publications (3)

Publication Number Publication Date
ITRM20000432A0 ITRM20000432A0 (it) 2000-08-01
ITRM20000432A1 ITRM20000432A1 (it) 2002-02-01
IT1317884B1 true IT1317884B1 (it) 2003-07-15

Family

ID=11454865

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000RM000432A IT1317884B1 (it) 2000-08-01 2000-08-01 Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica.

Country Status (20)

Country Link
US (1) US6710041B2 (it)
EP (1) EP1307463B1 (it)
JP (1) JP2004505090A (it)
KR (1) KR100826304B1 (it)
CN (1) CN1264848C (it)
AT (1) ATE287890T1 (it)
AU (2) AU2001284391B2 (it)
BR (1) BR0112843A (it)
CA (1) CA2415475C (it)
CZ (1) CZ299340B6 (it)
DE (1) DE60108642T2 (it)
DK (1) DK1307463T3 (it)
ES (1) ES2236291T3 (it)
HK (1) HK1059774A1 (it)
IT (1) IT1317884B1 (it)
MX (1) MXPA03000775A (it)
PL (1) PL203096B1 (it)
PT (1) PT1307463E (it)
SK (1) SK287248B6 (it)
WO (1) WO2002010175A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040178A1 (it) * 2004-04-07 2004-07-07 Sigma Tau Ind Farmaceuti Composti ad attivita' antipsicotica atipica.
ITRM20040222A1 (it) * 2004-05-07 2004-08-07 Sigma Tau Ind Farmaceuti Derivati dealchilati di pirrolo[2,1-b]benzotiazepine ad attivita' antipsicotica atipica.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1301965B1 (it) * 1998-07-28 2000-07-20 Sigma Tau Ind Farmaceuti Pirrolo (2,1-b)(1,3) benzotiazepine con attivita' antipsicoticaatipica.

Also Published As

Publication number Publication date
SK287248B6 (sk) 2010-04-07
CA2415475C (en) 2010-09-28
CZ299340B6 (cs) 2008-06-25
EP1307463B1 (en) 2005-01-26
ITRM20000432A0 (it) 2000-08-01
EP1307463A1 (en) 2003-05-07
ITRM20000432A1 (it) 2002-02-01
DE60108642T2 (de) 2006-06-14
DK1307463T3 (da) 2005-05-23
PT1307463E (pt) 2005-04-29
DE60108642D1 (de) 2005-03-03
KR100826304B1 (ko) 2008-04-29
WO2002010175A1 (en) 2002-02-07
CA2415475A1 (en) 2002-02-07
PL203096B1 (pl) 2009-08-31
ATE287890T1 (de) 2005-02-15
BR0112843A (pt) 2003-04-22
CZ200312A3 (cs) 2003-05-14
MXPA03000775A (es) 2003-10-15
CN1444588A (zh) 2003-09-24
SK1302003A3 (en) 2003-05-02
HK1059774A1 (en) 2004-07-16
US6710041B2 (en) 2004-03-23
KR20030019598A (ko) 2003-03-06
US20030186959A1 (en) 2003-10-02
AU2001284391B2 (en) 2006-09-28
PL365008A1 (en) 2004-12-27
ES2236291T3 (es) 2005-07-16
AU8439101A (en) 2002-02-13
CN1264848C (zh) 2006-07-19
JP2004505090A (ja) 2004-02-19

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