SK286978B6 - Použitie jednoreťazcovej protilátky schopnej špecificky viazať epitop prítomný v C-koncovej oblasti proteínu p53 medzi zvyškami 320-393 a nukleovej kyseliny kódujúcej takúto protilátku na prípravu farmaceutickej kompozície na liečbu rakovín - Google Patents

Použitie jednoreťazcovej protilátky schopnej špecificky viazať epitop prítomný v C-koncovej oblasti proteínu p53 medzi zvyškami 320-393 a nukleovej kyseliny kódujúcej takúto protilátku na prípravu farmaceutickej kompozície na liečbu rakovín Download PDF

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Publication number
SK286978B6
SK286978B6 SK558-99A SK55899A SK286978B6 SK 286978 B6 SK286978 B6 SK 286978B6 SK 55899 A SK55899 A SK 55899A SK 286978 B6 SK286978 B6 SK 286978B6
Authority
SK
Slovakia
Prior art keywords
protein
nucleic acid
vector
use according
ser
Prior art date
Application number
SK558-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK55899A3 (en
Inventor
Laurent Bracco
Laurent Debussche
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of SK55899A3 publication Critical patent/SK55899A3/sk
Publication of SK286978B6 publication Critical patent/SK286978B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK558-99A 1996-10-29 1997-10-27 Použitie jednoreťazcovej protilátky schopnej špecificky viazať epitop prítomný v C-koncovej oblasti proteínu p53 medzi zvyškami 320-393 a nukleovej kyseliny kódujúcej takúto protilátku na prípravu farmaceutickej kompozície na liečbu rakovín SK286978B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9613176A FR2755144B1 (fr) 1996-10-29 1996-10-29 Fragments d'anticorps a chaine unique anti-p53 et utilisation
PCT/FR1997/001921 WO1998018825A1 (fr) 1996-10-29 1997-10-27 Fragments d'anticorps a chaine unique anti-p53 et utilisations

Publications (2)

Publication Number Publication Date
SK55899A3 SK55899A3 (en) 2000-06-12
SK286978B6 true SK286978B6 (sk) 2009-08-06

Family

ID=9497134

Family Applications (1)

Application Number Title Priority Date Filing Date
SK558-99A SK286978B6 (sk) 1996-10-29 1997-10-27 Použitie jednoreťazcovej protilátky schopnej špecificky viazať epitop prítomný v C-koncovej oblasti proteínu p53 medzi zvyškami 320-393 a nukleovej kyseliny kódujúcej takúto protilátku na prípravu farmaceutickej kompozície na liečbu rakovín

Country Status (21)

Country Link
US (1) US6852509B1 (hu)
EP (1) EP0941252B1 (hu)
JP (1) JP4371178B2 (hu)
KR (1) KR100874789B1 (hu)
AT (1) ATE380198T1 (hu)
AU (1) AU745530B2 (hu)
BR (1) BR9712575A (hu)
CA (1) CA2268865C (hu)
CZ (1) CZ300526B6 (hu)
DE (1) DE69738352T2 (hu)
DK (1) DK0941252T3 (hu)
ES (1) ES2297853T3 (hu)
FR (1) FR2755144B1 (hu)
HU (1) HU226330B1 (hu)
IL (2) IL129476A0 (hu)
NO (1) NO326452B1 (hu)
PT (1) PT941252E (hu)
SI (1) SI0941252T1 (hu)
SK (1) SK286978B6 (hu)
WO (1) WO1998018825A1 (hu)
ZA (1) ZA979738B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121041A0 (en) 1997-06-09 1997-11-20 Yeda Res & Dev Immunogenic compositions for induction of anti-tumor immunity
US7199809B1 (en) 1998-10-19 2007-04-03 Symyx Technologies, Inc. Graphic design of combinatorial material libraries
AUPP932199A0 (en) * 1999-03-19 1999-04-15 St Vincent's Hospital Sydney Limited Anti-p53 antibodies
AU769679B2 (en) * 1999-03-19 2004-01-29 St Vincent's Hospital Sydney Limited Anti-p53 antibodies
DE19962583A1 (de) * 1999-12-23 2001-06-28 Mueller Hermelink Hans Konrad Antikörper gegen Plasmazellen
US6630584B1 (en) * 2000-03-16 2003-10-07 Ramot At Tel-Aviv University Ltd. Single chain antibody against mutant p53
EP1709973A1 (en) * 2003-12-24 2006-10-11 Locomogene, Inc. Method of suppressing cancer
JPWO2005061007A1 (ja) * 2003-12-24 2007-07-12 学校法人 聖マリアンナ医科大学 癌の抑制方法
GB0420771D0 (en) * 2004-09-17 2004-10-20 Randox Lab Ltd Antibody
ATE437185T1 (de) 2005-03-25 2009-08-15 Univ Ramot Gegen das gemeinsame epitop von mutierten p53 gerichtete humane synthetische einzelkettenantikörper und anwendungen davon
WO2007028117A2 (en) * 2005-09-02 2007-03-08 New England Medical Center Hospitals, Inc. P8 as a marker for heart failure
JP7481726B2 (ja) * 2016-05-02 2024-05-13 プロセナ バイオサイエンシーズ リミテッド タウ認識抗体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224784D0 (en) * 1992-11-26 1993-01-13 Univ Dundee Cellular protein
FR2732348B1 (fr) * 1995-03-31 1997-04-30 Rhone Poulenc Rorer Sa Systeme d'expression conditionnel
FR2736915B1 (fr) 1995-07-19 1997-08-22 Rhone Poulenc Rorer Sa Variants de la proteine p53 et utilisations therapeutiques

Also Published As

Publication number Publication date
WO1998018825A1 (fr) 1998-05-07
DE69738352D1 (de) 2008-01-17
AU745530B2 (en) 2002-03-21
BR9712575A (pt) 1999-10-19
NO991729L (no) 1999-04-13
PT941252E (pt) 2008-03-07
DK0941252T3 (da) 2008-03-31
CZ145599A3 (cs) 1999-08-11
NO991729D0 (no) 1999-04-13
FR2755144A1 (fr) 1998-04-30
IL129476A0 (en) 2000-02-29
JP4371178B2 (ja) 2009-11-25
HU226330B1 (en) 2008-09-29
SI0941252T1 (sl) 2008-04-30
ZA979738B (en) 1998-05-22
HUP9904199A3 (en) 2000-09-28
CA2268865C (fr) 2011-01-04
US6852509B1 (en) 2005-02-08
ES2297853T3 (es) 2008-05-01
FR2755144B1 (fr) 1998-11-27
EP0941252B1 (fr) 2007-12-05
KR20000052845A (ko) 2000-08-25
ATE380198T1 (de) 2007-12-15
HUP9904199A1 (hu) 2000-04-28
KR100874789B1 (ko) 2008-12-18
IL129476A (en) 2010-05-17
CA2268865A1 (fr) 1998-05-07
AU4952097A (en) 1998-05-22
EP0941252A1 (fr) 1999-09-15
DE69738352T2 (de) 2008-11-13
NO326452B1 (no) 2008-12-08
JP2001502553A (ja) 2001-02-27
CZ300526B6 (cs) 2009-06-10
SK55899A3 (en) 2000-06-12

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20121027