SK286384B6 - Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie - Google Patents

Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie Download PDF

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Publication number
SK286384B6
SK286384B6 SK848-2002A SK8482002A SK286384B6 SK 286384 B6 SK286384 B6 SK 286384B6 SK 8482002 A SK8482002 A SK 8482002A SK 286384 B6 SK286384 B6 SK 286384B6
Authority
SK
Slovakia
Prior art keywords
polypeptide
seq
antibody
amino acids
amino acid
Prior art date
Application number
SK848-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK8482002A3 (en
Inventor
Richard Harkins
Deborah Parkes
Gordon Parry
Douglas W. Schneider
Renate Steinbrecher
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of SK8482002A3 publication Critical patent/SK8482002A3/sk
Publication of SK286384B6 publication Critical patent/SK286384B6/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
SK848-2002A 1999-12-16 2000-12-15 Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie SK286384B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17237099P 1999-12-16 1999-12-16
US09/732,357 US6682902B2 (en) 1999-12-16 2000-12-07 DNA encoding a novel RG1 polypeptide
PCT/US2000/033901 WO2001044291A2 (en) 1999-12-16 2000-12-15 Polynucleotid encoding the rg1 polypeptide

Publications (2)

Publication Number Publication Date
SK8482002A3 SK8482002A3 (en) 2003-02-04
SK286384B6 true SK286384B6 (sk) 2008-08-05

Family

ID=26868022

Family Applications (2)

Application Number Title Priority Date Filing Date
SK848-2002A SK286384B6 (sk) 1999-12-16 2000-12-15 Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie
SK5055-2008A SK288147B6 (sk) 1999-12-16 2000-12-15 Isolated antibody or antibody fragment, which specifically bind to RG1 polypeptide, and immunoconjugate

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK5055-2008A SK288147B6 (sk) 1999-12-16 2000-12-15 Isolated antibody or antibody fragment, which specifically bind to RG1 polypeptide, and immunoconjugate

Country Status (32)

Country Link
US (5) US6682902B2 (hr)
EP (2) EP1237915B1 (hr)
JP (1) JP4979867B2 (hr)
KR (1) KR100752434B1 (hr)
CN (1) CN1297566C (hr)
AT (1) ATE440862T1 (hr)
AU (1) AU784674B2 (hr)
BG (1) BG65898B1 (hr)
BR (1) BR0017022A (hr)
CA (1) CA2394574A1 (hr)
CZ (1) CZ299232B6 (hr)
DE (1) DE60042836D1 (hr)
DK (1) DK1237915T3 (hr)
EE (1) EE05293B1 (hr)
ES (1) ES2331106T3 (hr)
HR (1) HRP20020549B1 (hr)
HU (1) HU229001B1 (hr)
IL (2) IL150115A0 (hr)
LT (1) LT5046B (hr)
ME (1) MEP37808A (hr)
MX (1) MXPA02005914A (hr)
NO (1) NO330924B1 (hr)
NZ (1) NZ519598A (hr)
PL (1) PL207634B1 (hr)
PT (1) PT1237915E (hr)
RO (1) RO122543B1 (hr)
RS (1) RS50831B (hr)
RU (1) RU2283130C2 (hr)
SI (2) SI1237915T1 (hr)
SK (2) SK286384B6 (hr)
WO (1) WO2001044291A2 (hr)
ZA (1) ZA200205638B (hr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

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US20020161199A1 (en) * 1998-04-08 2002-10-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP1251139A3 (en) * 1998-04-08 2002-12-18 Genentech, Inc. Human mindin-like protein and nucleic acids encoding it
US6960433B1 (en) 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20070031901A1 (en) * 1999-03-08 2007-02-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
KR101215218B1 (ko) * 2003-07-22 2012-12-26 바이엘 파마 악티엔게젤샤프트 Rg1 항체 및 그의 용도
US7294704B2 (en) 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
TWI610939B (zh) * 2007-02-21 2018-01-11 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
AR069746A1 (es) * 2007-11-30 2010-02-17 Medarex Inc Conjugados de anticuerpos anti- rg-1
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN102346184B (zh) * 2010-08-03 2014-03-26 中国人民解放军军事医学科学院生物工程研究所 Spon2的新用途

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US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
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US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
KR100272077B1 (ko) 1990-08-29 2000-11-15 젠팜인터내셔날,인코포레이티드 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
JPH08502950A (ja) 1992-05-14 1996-04-02 リボザイム・ファーマシューティカルズ・インコーポレイテッド 癌増殖を抑制する方法及び試薬
US5871969A (en) 1996-02-12 1999-02-16 Human Genome Sciences, Inc. Nucleic acids encoding human neuronal attachment factor-1
US6177244B1 (en) * 1996-05-10 2001-01-23 Beth Israel Deaconess Medical Center Inc. NPG-1 gene that is differentially expressed in prostate tumors
US6287777B1 (en) * 1996-05-10 2001-09-11 Beth Israel Deaconess Medical Center NPG-1 gene that is differentially expressed in prostate tumors
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JP4065326B2 (ja) * 1996-08-26 2008-03-26 ユニバーシティ・オブ・ワシントン パーレカンドメインiスプライシング変異体の治療および診断への利用
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CN1268178A (zh) * 1997-05-06 2000-09-27 人体基因组科学有限公司 粪肠球菌多核苷酸和多肽
WO1998050073A1 (en) 1997-05-09 1998-11-12 Smithkline Beecham Corporation Integrin ligand, human mindin
DK1490386T3 (da) 1998-03-10 2008-12-15 Genentech Inc Nyt polypeptid og nukleinsyrer kodende for dette
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US6960433B1 (en) * 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
WO2000023108A1 (en) 1998-10-19 2000-04-27 Diadexus Llc Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US6682736B1 (en) * 1998-12-23 2004-01-27 Abgenix, Inc. Human monoclonal antibodies to CTLA-4
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
DE202012012998U1 (de) 2011-08-31 2014-06-13 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

Also Published As

Publication number Publication date
PT1237915E (pt) 2009-11-04
RS50831B (sr) 2010-08-31
CZ299232B6 (cs) 2008-05-21
SI21140A (sl) 2003-08-31
HRP20020549B1 (hr) 2013-09-30
US7893217B2 (en) 2011-02-22
BG65898B1 (bg) 2010-04-30
NZ519598A (en) 2004-03-26
WO2001044291A3 (en) 2002-01-17
HRP20020549A2 (en) 2004-04-30
IL150115A0 (en) 2002-12-01
HU229001B1 (en) 2013-07-29
LT5046B (lt) 2003-08-25
YU44602A (sh) 2005-06-10
MEP37808A (en) 2011-05-10
SI1237915T1 (sl) 2009-12-31
AU3074601A (en) 2001-06-25
PL356220A1 (en) 2004-06-28
RU2283130C2 (ru) 2006-09-10
EP1237915A2 (en) 2002-09-11
ZA200205638B (en) 2003-10-15
RU2002119208A (ru) 2004-02-27
EE200200323A (et) 2003-10-15
US6682902B2 (en) 2004-01-27
DK1237915T3 (da) 2009-11-16
ATE440862T1 (de) 2009-09-15
US20040152139A1 (en) 2004-08-05
NO330924B1 (no) 2011-08-22
RO122543B1 (ro) 2009-08-28
HUP0204224A2 (hu) 2003-03-28
BG106823A (bg) 2003-04-30
EP2048157B1 (en) 2012-10-10
CA2394574A1 (en) 2001-06-21
CN1297566C (zh) 2007-01-31
PL207634B1 (pl) 2011-01-31
IL150115A (en) 2013-11-28
SK8482002A3 (en) 2003-02-04
NO20022836L (no) 2002-08-15
BR0017022A (pt) 2002-11-05
US20090292112A1 (en) 2009-11-26
KR100752434B1 (ko) 2007-08-27
US7887804B2 (en) 2011-02-15
EP1237915B1 (en) 2009-08-26
CN1434832A (zh) 2003-08-06
LT2002070A (en) 2003-04-25
NO20022836D0 (no) 2002-06-14
US20040023307A1 (en) 2004-02-05
US20020004047A1 (en) 2002-01-10
SK288147B6 (sk) 2013-12-02
ES2331106T3 (es) 2009-12-22
JP4979867B2 (ja) 2012-07-18
DE60042836D1 (de) 2009-10-08
WO2001044291A2 (en) 2001-06-21
HUP0204224A3 (en) 2004-12-28
US20090214422A1 (en) 2009-08-27
EP2048157A1 (en) 2009-04-15
EE05293B1 (et) 2010-04-15
AU784674B2 (en) 2006-05-25
US7307154B2 (en) 2007-12-11
KR20020065575A (ko) 2002-08-13
JP2003521244A (ja) 2003-07-15
MXPA02005914A (es) 2003-02-27

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20141215