SK286270B6 - Spôsob výroby zmesi námeľových vločiek - Google Patents
Spôsob výroby zmesi námeľových vločiek Download PDFInfo
- Publication number
- SK286270B6 SK286270B6 SK232-2004A SK2322004A SK286270B6 SK 286270 B6 SK286270 B6 SK 286270B6 SK 2322004 A SK2322004 A SK 2322004A SK 286270 B6 SK286270 B6 SK 286270B6
- Authority
- SK
- Slovakia
- Prior art keywords
- ergot
- flake
- particles
- mesh
- mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 48
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 8
- 238000000605 extraction Methods 0.000 claims abstract description 52
- 239000012535 impurity Substances 0.000 claims abstract description 34
- 238000011282 treatment Methods 0.000 claims abstract description 20
- 229960003133 ergot alkaloid Drugs 0.000 claims abstract description 15
- 238000000926 separation method Methods 0.000 claims abstract description 15
- 239000002245 particle Substances 0.000 claims description 97
- 238000000034 method Methods 0.000 claims description 48
- 210000002421 cell wall Anatomy 0.000 claims description 31
- 238000009826 distribution Methods 0.000 claims description 20
- 239000000428 dust Substances 0.000 claims description 19
- 241000576755 Sclerotia Species 0.000 claims description 18
- 230000002093 peripheral effect Effects 0.000 claims description 17
- 208000034189 Sclerosis Diseases 0.000 claims description 7
- 229910010293 ceramic material Inorganic materials 0.000 claims description 7
- 230000036961 partial effect Effects 0.000 claims description 7
- 238000007873 sieving Methods 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 3
- 230000003179 granulation Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 description 26
- 230000002784 sclerotic effect Effects 0.000 description 14
- 239000003795 chemical substances by application Substances 0.000 description 11
- 230000005484 gravity Effects 0.000 description 10
- 238000005189 flocculation Methods 0.000 description 9
- 230000016615 flocculation Effects 0.000 description 9
- 238000005029 sieve analysis Methods 0.000 description 9
- 229910000831 Steel Inorganic materials 0.000 description 8
- 239000010959 steel Substances 0.000 description 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- YDOTUXAWKBPQJW-UHFFFAOYSA-N alpha-Ergocryptinine Natural products C1=CC(C=2C(N(C)CC(C=2)C(=O)NC2(C(=O)N3C(C(N4CCCC4C3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=CNC3=C1 YDOTUXAWKBPQJW-UHFFFAOYSA-N 0.000 description 6
- 229950001817 alpha-ergocryptine Drugs 0.000 description 6
- 230000005294 ferromagnetic effect Effects 0.000 description 6
- 239000002923 metal particle Substances 0.000 description 6
- 230000005298 paramagnetic effect Effects 0.000 description 6
- 239000004575 stone Substances 0.000 description 6
- 239000002023 wood Substances 0.000 description 6
- 241000209056 Secale Species 0.000 description 5
- 239000013543 active substance Substances 0.000 description 5
- 239000004464 cereal grain Substances 0.000 description 5
- 229910017052 cobalt Inorganic materials 0.000 description 5
- 239000010941 cobalt Substances 0.000 description 5
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 5
- 230000005291 magnetic effect Effects 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 239000002689 soil Substances 0.000 description 5
- UONOETXJSWQNOL-UHFFFAOYSA-N tungsten carbide Chemical compound [W+]#[C-] UONOETXJSWQNOL-UHFFFAOYSA-N 0.000 description 5
- 239000002904 solvent Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- YDOTUXAWKBPQJW-NSLWYYNWSA-N alpha-ergocryptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=CNC3=C1 YDOTUXAWKBPQJW-NSLWYYNWSA-N 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000001788 irregular Effects 0.000 description 3
- 239000006148 magnetic separator Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 150000003797 alkaloid derivatives Chemical class 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- OFKDAAIKGIBASY-VFGNJEKYSA-N ergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2C(C3=CC=CC4=NC=C([C]34)C2)=C1)C)C1=CC=CC=C1 OFKDAAIKGIBASY-VFGNJEKYSA-N 0.000 description 2
- 229960004943 ergotamine Drugs 0.000 description 2
- XCGSFFUVFURLIX-UHFFFAOYSA-N ergotaminine Natural products C1=C(C=2C=CC=C3NC=C(C=23)C2)C2N(C)CC1C(=O)NC(C(N12)=O)(C)OC1(O)C1CCCN1C(=O)C2CC1=CC=CC=C1 XCGSFFUVFURLIX-UHFFFAOYSA-N 0.000 description 2
- 238000011194 good manufacturing practice Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000001033 granulometry Methods 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000221751 Claviceps purpurea Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- -1 earth Substances 0.000 description 1
- XLMJRFCCCWFQRE-SJRQCXNHSA-N ecboline Chemical compound C([C@H]1[C@]2(O)O3)CCN1C(=O)CN2C(=O)[C@]3(C(C)C)NC(=O)[C@@H](CN(C)[C@@H]1C2)C=C1C1=C3C2=CNC3=CC=C1 XLMJRFCCCWFQRE-SJRQCXNHSA-N 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- ZAGRKAFMISFKIO-QMTHXVAHSA-N lysergic acid Chemical class C1=CC(C2=C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-QMTHXVAHSA-N 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 239000011369 resultant mixture Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000007788 roughening Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000008646 thermal stress Effects 0.000 description 1
Landscapes
- Combined Means For Separation Of Solids (AREA)
- Crushing And Grinding (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ20040623A CZ296469B6 (cs) | 2004-05-18 | 2004-05-18 | Zpusob výroby smesi námelových vlocek |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK2322004A3 SK2322004A3 (en) | 2004-11-03 |
| SK286270B6 true SK286270B6 (sk) | 2008-06-06 |
Family
ID=33304500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK232-2004A SK286270B6 (sk) | 2004-05-18 | 2004-05-27 | Spôsob výroby zmesi námeľových vločiek |
Country Status (2)
| Country | Link |
|---|---|
| CZ (1) | CZ296469B6 (cs) |
| SK (1) | SK286270B6 (cs) |
-
2004
- 2004-05-18 CZ CZ20040623A patent/CZ296469B6/cs not_active IP Right Cessation
- 2004-05-27 SK SK232-2004A patent/SK286270B6/sk not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2004623A3 (cs) | 2004-11-10 |
| CZ296469B6 (cs) | 2006-03-15 |
| SK2322004A3 (en) | 2004-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4A | Patent expired |
Expiry date: 20240527 |