SK284767B6 - Spôsob prípravy derivátov deazaadenozínov substituovaných v polohe N6 - Google Patents

Spôsob prípravy derivátov deazaadenozínov substituovaných v polohe N6 Download PDF

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Publication number
SK284767B6
SK284767B6 SK907-2001A SK9072001A SK284767B6 SK 284767 B6 SK284767 B6 SK 284767B6 SK 9072001 A SK9072001 A SK 9072001A SK 284767 B6 SK284767 B6 SK 284767B6
Authority
SK
Slovakia
Prior art keywords
amino
methyl
propyl
chlorothien
alkyl
Prior art date
Application number
SK907-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK9072001A3 (en
Inventor
Diane C. Salazar (Zosnul�)
Walter Rodriguez
James P. Sherbine
Rick G. Woodward
Adam W. Sledeski
Matthew R. Powers
Michael K. O'brien
Original Assignee
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.
Publication of SK9072001A3 publication Critical patent/SK9072001A3/sk
Publication of SK284767B6 publication Critical patent/SK284767B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK907-2001A 1998-12-21 1999-12-14 Spôsob prípravy derivátov deazaadenozínov substituovaných v polohe N6 SK284767B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11307798P 1998-12-21 1998-12-21
PCT/US1999/029643 WO2000037469A2 (en) 1998-12-21 1999-12-14 Process for preparing n6-substituted deaza-adenosine derivatives

Publications (2)

Publication Number Publication Date
SK9072001A3 SK9072001A3 (en) 2001-12-03
SK284767B6 true SK284767B6 (sk) 2005-11-03

Family

ID=22347487

Family Applications (1)

Application Number Title Priority Date Filing Date
SK907-2001A SK284767B6 (sk) 1998-12-21 1999-12-14 Spôsob prípravy derivátov deazaadenozínov substituovaných v polohe N6

Country Status (28)

Country Link
US (1) US6184382B1 (no)
EP (1) EP1175420B1 (no)
JP (1) JP2002533343A (no)
KR (1) KR20010087425A (no)
CN (1) CN1122667C (no)
AP (1) AP1336A (no)
AT (1) ATE235493T1 (no)
AU (1) AU774155B2 (no)
BG (1) BG105624A (no)
BR (1) BR9917088A (no)
CA (1) CA2357760A1 (no)
CZ (1) CZ20012283A3 (no)
DE (1) DE69906392T2 (no)
DK (1) DK1175420T3 (no)
EA (1) EA003645B1 (no)
EE (1) EE200100333A (no)
ES (1) ES2191489T3 (no)
HK (1) HK1041607A1 (no)
HU (1) HUP0105224A3 (no)
ID (1) ID30118A (no)
IL (1) IL143843A0 (no)
NO (1) NO319789B1 (no)
NZ (1) NZ512500A (no)
PL (1) PL349154A1 (no)
PT (1) PT1175420E (no)
SK (1) SK284767B6 (no)
WO (1) WO2000037469A2 (no)
YU (1) YU51401A (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1063A (en) * 1996-12-11 2002-04-26 Aventis Pharmaceuticals Products Inc Preparation of [1s-[1a, 2b, 3b, 4a(S*)]-4-[7-[[1-3-chloro-2-thienyl) metthyl]propyl]amino]-3h-imidazo[4, 5-b]pyridin-3-YL]-N-ethyl-2,3-dihydroxycypentanecarboxamide.
KR100446669B1 (ko) * 2002-04-04 2004-09-04 (주) 비엔씨바이오팜 2-(헤테로사이클릭-알킬아미노)피리딘 유도체, 그제조방법 및 이를 포함하는 항바이러스용 약학적 조성물
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU654507B2 (en) * 1990-09-25 1994-11-10 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
US5652366A (en) * 1990-09-25 1997-07-29 Rhone-Poulenc Rorer Pharmaceuticals Inc. DI (1R)-(-)camphosulfonic acid) salt, preparation thereof and use thereof

Also Published As

Publication number Publication date
EA003645B1 (ru) 2003-08-28
WO2000037469A3 (en) 2000-09-14
PL349154A1 (en) 2002-07-01
WO2000037469A2 (en) 2000-06-29
AU774155B2 (en) 2004-06-17
CN1122667C (zh) 2003-10-01
EP1175420A2 (en) 2002-01-30
ATE235493T1 (de) 2003-04-15
AU2181400A (en) 2000-07-12
JP2002533343A (ja) 2002-10-08
BR9917088A (pt) 2006-01-31
NO20013044D0 (no) 2001-06-19
HUP0105224A2 (en) 2002-06-29
KR20010087425A (ko) 2001-09-15
EE200100333A (et) 2002-08-15
US6184382B1 (en) 2001-02-06
HK1041607A1 (zh) 2002-07-12
BG105624A (en) 2002-01-31
ES2191489T3 (es) 2003-09-01
EP1175420B1 (en) 2003-03-26
DE69906392D1 (de) 2003-04-30
DE69906392T2 (de) 2004-02-05
IL143843A0 (en) 2002-04-21
AP1336A (en) 2004-11-30
NO20013044L (no) 2001-08-20
NZ512500A (en) 2003-01-31
EA200100697A1 (ru) 2001-12-24
DK1175420T3 (da) 2003-07-07
CA2357760A1 (en) 2000-06-29
HUP0105224A3 (en) 2003-01-28
WO2000037469B1 (en) 2000-11-02
CN1333773A (zh) 2002-01-30
CZ20012283A3 (cs) 2001-10-17
PT1175420E (pt) 2003-08-29
AP2001002200A0 (en) 2001-09-30
SK9072001A3 (en) 2001-12-03
ID30118A (id) 2001-11-08
YU51401A (sh) 2003-12-31
NO319789B1 (no) 2005-09-12

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