SK284186B6 - Substituované cykloheptény, spôsob ich výroby a ich použitie - Google Patents

Substituované cykloheptény, spôsob ich výroby a ich použitie Download PDF

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Publication number
SK284186B6
SK284186B6 SK1742-99A SK174299A SK284186B6 SK 284186 B6 SK284186 B6 SK 284186B6 SK 174299 A SK174299 A SK 174299A SK 284186 B6 SK284186 B6 SK 284186B6
Authority
SK
Slovakia
Prior art keywords
formula
hydrochloride
dimethylaminomethyl
alkyl
phenyl
Prior art date
Application number
SK1742-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK174299A3 (en
Inventor
Osvald Zimmer
Wolfgang Werner Alfred Strassburger
G�Nter Werner Englberger
Babette-Yvonne Kgel
Original Assignee
Grnenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grnenthal Gmbh filed Critical Grnenthal Gmbh
Publication of SK174299A3 publication Critical patent/SK174299A3/sk
Publication of SK284186B6 publication Critical patent/SK284186B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C13/00Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
    • C07C13/02Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
    • C07C13/16Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a six-membered ring
    • C07C13/18Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a six-membered ring with a cyclohexane ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/18Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
SK1742-99A 1998-12-14 1999-12-13 Substituované cykloheptény, spôsob ich výroby a ich použitie SK284186B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19857475A DE19857475A1 (de) 1998-12-14 1998-12-14 Substituierte Cycloheptene, deren Herstellung und Verwendung

Publications (2)

Publication Number Publication Date
SK174299A3 SK174299A3 (en) 2000-07-11
SK284186B6 true SK284186B6 (sk) 2004-10-05

Family

ID=7890934

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1742-99A SK284186B6 (sk) 1998-12-14 1999-12-13 Substituované cykloheptény, spôsob ich výroby a ich použitie

Country Status (27)

Country Link
US (1) US6323369B1 (da)
EP (1) EP1010689B1 (da)
JP (1) JP4440398B2 (da)
KR (1) KR20000048101A (da)
CN (1) CN1231457C (da)
AR (1) AR021616A1 (da)
AT (1) ATE231119T1 (da)
AU (1) AU767102B2 (da)
BR (1) BR9907340A (da)
CA (1) CA2292017C (da)
CZ (1) CZ296788B6 (da)
DE (2) DE19857475A1 (da)
DK (1) DK1010689T3 (da)
ES (1) ES2190632T3 (da)
HK (1) HK1028595A1 (da)
HU (1) HU224313B1 (da)
IL (1) IL133481A (da)
NO (1) NO313826B1 (da)
NZ (1) NZ501651A (da)
PE (1) PE20001328A1 (da)
PL (1) PL199875B1 (da)
PT (1) PT1010689E (da)
RU (1) RU2233268C2 (da)
SI (1) SI1010689T1 (da)
SK (1) SK284186B6 (da)
UY (1) UY25841A1 (da)
ZA (1) ZA997637B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10261091A1 (de) 2002-12-20 2004-07-01 Grünenthal GmbH Gesättigte und ungesättigte Heteroarylcycloalkylmethyl-Amine
DE10326097A1 (de) * 2003-06-06 2005-01-05 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen
DE102004034619A1 (de) * 2004-07-16 2006-02-23 Grünenthal GmbH Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
CN103965059B (zh) * 2013-02-06 2017-12-22 上海科胜药物研发有限公司 一种制备(1r,2s)‑2‑(3,4‑二氟苯基)环丙胺的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518663A1 (de) * 1965-08-02 1969-12-18 Gruenenthal Chemie Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung
US3830934A (en) * 1967-07-27 1974-08-20 Gruenenthal Chemie Analgesic and antitussive compositions and methods

Also Published As

Publication number Publication date
HU224313B1 (hu) 2005-07-28
HK1028595A1 (en) 2001-02-23
KR20000048101A (ko) 2000-07-25
EP1010689B1 (de) 2003-01-15
AU6440699A (en) 2000-06-15
DK1010689T3 (da) 2003-02-10
HU9904564D0 (en) 2000-02-28
CZ451499A3 (cs) 2000-07-12
UY25841A1 (es) 2000-09-29
RU2233268C2 (ru) 2004-07-27
JP2000178238A (ja) 2000-06-27
ATE231119T1 (de) 2003-02-15
ES2190632T3 (es) 2003-08-01
US6323369B1 (en) 2001-11-27
HUP9904564A2 (hu) 2000-12-28
PL199875B1 (pl) 2008-11-28
SI1010689T1 (en) 2003-06-30
HUP9904564A3 (en) 2001-01-29
IL133481A (en) 2004-05-12
JP4440398B2 (ja) 2010-03-24
NO313826B1 (no) 2002-12-09
BR9907340A (pt) 2001-01-16
PE20001328A1 (es) 2000-12-23
CA2292017C (en) 2009-09-08
CZ296788B6 (cs) 2006-06-14
AU767102B2 (en) 2003-10-30
NZ501651A (en) 2000-12-22
PL337154A1 (en) 2000-06-19
NO996156D0 (no) 1999-12-13
DE19857475A1 (de) 2000-06-15
NO996156L (no) 2000-06-15
IL133481A0 (en) 2001-04-30
ZA997637B (en) 2000-06-14
SK174299A3 (en) 2000-07-11
CN1266053A (zh) 2000-09-13
DE59904035D1 (de) 2003-02-20
AR021616A1 (es) 2002-07-31
CN1231457C (zh) 2005-12-14
EP1010689A1 (de) 2000-06-21
CA2292017A1 (en) 2000-06-14
PT1010689E (pt) 2003-06-30

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20111213