IL133481A - Transformed cycloheptanes, their preparation and pharmaceutical preparations containing them - Google Patents

Transformed cycloheptanes, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL133481A
IL133481A IL13348199A IL13348199A IL133481A IL 133481 A IL133481 A IL 133481A IL 13348199 A IL13348199 A IL 13348199A IL 13348199 A IL13348199 A IL 13348199A IL 133481 A IL133481 A IL 133481A
Authority
IL
Israel
Prior art keywords
enyl
cyclohept
aryl
phenol hydrochloride
dimethylaminomethyl
Prior art date
Application number
IL13348199A
Other languages
English (en)
Hebrew (he)
Other versions
IL133481A0 (en
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of IL133481A0 publication Critical patent/IL133481A0/xx
Publication of IL133481A publication Critical patent/IL133481A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
    • C07C13/02—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
    • C07C13/16—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a six-membered ring
    • C07C13/18—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a six-membered ring with a cyclohexane ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
IL13348199A 1998-12-14 1999-12-13 Transformed cycloheptanes, their preparation and pharmaceutical preparations containing them IL133481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19857475A DE19857475A1 (de) 1998-12-14 1998-12-14 Substituierte Cycloheptene, deren Herstellung und Verwendung

Publications (2)

Publication Number Publication Date
IL133481A0 IL133481A0 (en) 2001-04-30
IL133481A true IL133481A (en) 2004-05-12

Family

ID=7890934

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13348199A IL133481A (en) 1998-12-14 1999-12-13 Transformed cycloheptanes, their preparation and pharmaceutical preparations containing them

Country Status (27)

Country Link
US (1) US6323369B1 (da)
EP (1) EP1010689B1 (da)
JP (1) JP4440398B2 (da)
KR (1) KR20000048101A (da)
CN (1) CN1231457C (da)
AR (1) AR021616A1 (da)
AT (1) ATE231119T1 (da)
AU (1) AU767102B2 (da)
BR (1) BR9907340A (da)
CA (1) CA2292017C (da)
CZ (1) CZ296788B6 (da)
DE (2) DE19857475A1 (da)
DK (1) DK1010689T3 (da)
ES (1) ES2190632T3 (da)
HK (1) HK1028595A1 (da)
HU (1) HU224313B1 (da)
IL (1) IL133481A (da)
NO (1) NO313826B1 (da)
NZ (1) NZ501651A (da)
PE (1) PE20001328A1 (da)
PL (1) PL199875B1 (da)
PT (1) PT1010689E (da)
RU (1) RU2233268C2 (da)
SI (1) SI1010689T1 (da)
SK (1) SK284186B6 (da)
UY (1) UY25841A1 (da)
ZA (1) ZA997637B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10261091A1 (de) * 2002-12-20 2004-07-01 Grünenthal GmbH Gesättigte und ungesättigte Heteroarylcycloalkylmethyl-Amine
DE10326097A1 (de) * 2003-06-06 2005-01-05 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen
DE102004034619A1 (de) * 2004-07-16 2006-02-23 Grünenthal GmbH Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
CN103965059B (zh) * 2013-02-06 2017-12-22 上海科胜药物研发有限公司 一种制备(1r,2s)‑2‑(3,4‑二氟苯基)环丙胺的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1518663A1 (de) * 1965-08-02 1969-12-18 Gruenenthal Chemie Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung
US3830934A (en) * 1967-07-27 1974-08-20 Gruenenthal Chemie Analgesic and antitussive compositions and methods

Also Published As

Publication number Publication date
PL199875B1 (pl) 2008-11-28
EP1010689A1 (de) 2000-06-21
CZ296788B6 (cs) 2006-06-14
HU9904564D0 (en) 2000-02-28
HK1028595A1 (en) 2001-02-23
EP1010689B1 (de) 2003-01-15
IL133481A0 (en) 2001-04-30
DE19857475A1 (de) 2000-06-15
CA2292017A1 (en) 2000-06-14
SK284186B6 (sk) 2004-10-05
NO313826B1 (no) 2002-12-09
CN1231457C (zh) 2005-12-14
HUP9904564A3 (en) 2001-01-29
SI1010689T1 (en) 2003-06-30
DK1010689T3 (da) 2003-02-10
CN1266053A (zh) 2000-09-13
JP4440398B2 (ja) 2010-03-24
CZ451499A3 (cs) 2000-07-12
KR20000048101A (ko) 2000-07-25
JP2000178238A (ja) 2000-06-27
CA2292017C (en) 2009-09-08
SK174299A3 (en) 2000-07-11
ZA997637B (en) 2000-06-14
ES2190632T3 (es) 2003-08-01
NZ501651A (en) 2000-12-22
PT1010689E (pt) 2003-06-30
DE59904035D1 (de) 2003-02-20
PE20001328A1 (es) 2000-12-23
ATE231119T1 (de) 2003-02-15
US6323369B1 (en) 2001-11-27
NO996156L (no) 2000-06-15
RU2233268C2 (ru) 2004-07-27
AU6440699A (en) 2000-06-15
BR9907340A (pt) 2001-01-16
NO996156D0 (no) 1999-12-13
UY25841A1 (es) 2000-09-29
HUP9904564A2 (hu) 2000-12-28
AR021616A1 (es) 2002-07-31
PL337154A1 (en) 2000-06-19
AU767102B2 (en) 2003-10-30
HU224313B1 (hu) 2005-07-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees