SK283662B6 - Kompetetívne progesterónantagonisty na kontrolu samičej fertility zameranú podľa potreby - Google Patents
Kompetetívne progesterónantagonisty na kontrolu samičej fertility zameranú podľa potreby Download PDFInfo
- Publication number
- SK283662B6 SK283662B6 SK518-97A SK51897A SK283662B6 SK 283662 B6 SK283662 B6 SK 283662B6 SK 51897 A SK51897 A SK 51897A SK 283662 B6 SK283662 B6 SK 283662B6
- Authority
- SK
- Slovakia
- Prior art keywords
- hydroxy
- phenyl
- competitive progesterone
- progesterone antagonist
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4438820 | 1994-10-24 | ||
| PCT/EP1995/004191 WO1996012494A1 (de) | 1994-10-24 | 1995-10-24 | Kompetitive progesteronantagonisten zur bedarfsorientierten weiblichen fertilitätskontrolle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK51897A3 SK51897A3 (en) | 1997-09-10 |
| SK283662B6 true SK283662B6 (sk) | 2003-11-04 |
Family
ID=6532105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK518-97A SK283662B6 (sk) | 1994-10-24 | 1995-10-24 | Kompetetívne progesterónantagonisty na kontrolu samičej fertility zameranú podľa potreby |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6143754A (cs) |
| EP (1) | EP0787002B1 (cs) |
| JP (1) | JPH10507461A (cs) |
| KR (1) | KR970706827A (cs) |
| CN (1) | CN1211087C (cs) |
| AT (1) | ATE347894T1 (cs) |
| AU (1) | AU707235B2 (cs) |
| BG (1) | BG62877B1 (cs) |
| BR (1) | BR9509478A (cs) |
| CA (1) | CA2203541A1 (cs) |
| CZ (1) | CZ290690B6 (cs) |
| DE (1) | DE59511071D1 (cs) |
| DK (1) | DK0787002T3 (cs) |
| ES (1) | ES2279515T3 (cs) |
| FI (1) | FI971742A0 (cs) |
| HU (1) | HU226566B1 (cs) |
| IL (1) | IL115738A (cs) |
| NO (1) | NO314437B1 (cs) |
| NZ (1) | NZ295365A (cs) |
| PL (1) | PL319869A1 (cs) |
| PT (1) | PT787002E (cs) |
| RO (1) | RO120606B1 (cs) |
| SK (1) | SK283662B6 (cs) |
| WO (1) | WO1996012494A1 (cs) |
| ZA (1) | ZA959008B (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19745085A1 (de) * | 1997-10-11 | 1999-04-15 | Jenapharm Gmbh | 11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
| DE19809845A1 (de) | 1998-03-03 | 1999-09-09 | Jenapharm Gmbh | S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
| US7629334B1 (en) | 1999-08-31 | 2009-12-08 | Bayer Schering Pharma Aktiengesellschaft | Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT) |
| IL148417A0 (en) * | 1999-08-31 | 2002-09-12 | Jenapharm Gmbh | Mesoprogestins (progesterone receptor modulators) as a component of compositions for hormone replacement therapy (hrt) |
| IL148415A0 (en) * | 1999-08-31 | 2002-09-12 | Jenapharm Gmbh | Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives |
| DE102005050729A1 (de) * | 2005-10-19 | 2007-04-26 | Schering Ag | Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption |
| AU2008341138A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Women's Health, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
| EP2419108B1 (en) | 2009-04-14 | 2016-08-17 | Laboratoire HRA Pharma | Method for on-demand contraception |
| US20120129825A1 (en) * | 2009-04-14 | 2012-05-24 | Andre Ulmann | Method for on-demand contraception using levonorgestrel or norgestrel |
| JP6370887B2 (ja) | 2013-05-23 | 2018-08-08 | バイエル・ファルマ・アクティエンゲゼルシャフト | オンデマンド避妊のための医薬組成物およびその使用、ならびにこの医薬組成物の適用体制 |
| KR20170084086A (ko) | 2014-11-17 | 2017-07-19 | 아르노 테라퓨틱스 인코포레이티드 | 오나프리스톤 연장-방출 조성물 및 방법 |
| CA2998924A1 (en) | 2015-09-25 | 2017-03-30 | Context Biopharma Inc. | Methods of making onapristone intermediates |
| US10548905B2 (en) | 2015-12-15 | 2020-02-04 | Context Biopharma Inc. | Amorphous onapristone compositions and methods of making the same |
| US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5439913A (en) * | 1992-05-12 | 1995-08-08 | Schering Aktiengesellschaft | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
-
1995
- 1995-10-24 ES ES95937845T patent/ES2279515T3/es not_active Expired - Lifetime
- 1995-10-24 DK DK95937845T patent/DK0787002T3/da active
- 1995-10-24 CA CA002203541A patent/CA2203541A1/en not_active Abandoned
- 1995-10-24 JP JP8513655A patent/JPH10507461A/ja active Pending
- 1995-10-24 AT AT95937845T patent/ATE347894T1/de not_active IP Right Cessation
- 1995-10-24 NZ NZ295365A patent/NZ295365A/xx unknown
- 1995-10-24 RO RO97-00635A patent/RO120606B1/ro unknown
- 1995-10-24 PL PL95319869A patent/PL319869A1/xx unknown
- 1995-10-24 CZ CZ19971180A patent/CZ290690B6/cs not_active IP Right Cessation
- 1995-10-24 BR BR9509478A patent/BR9509478A/pt active Search and Examination
- 1995-10-24 HU HU9702177A patent/HU226566B1/hu not_active IP Right Cessation
- 1995-10-24 CN CNB951958178A patent/CN1211087C/zh not_active Expired - Fee Related
- 1995-10-24 DE DE59511071T patent/DE59511071D1/de not_active Expired - Fee Related
- 1995-10-24 WO PCT/EP1995/004191 patent/WO1996012494A1/de active IP Right Grant
- 1995-10-24 EP EP95937845A patent/EP0787002B1/de not_active Expired - Lifetime
- 1995-10-24 PT PT95937845T patent/PT787002E/pt unknown
- 1995-10-24 AU AU38696/95A patent/AU707235B2/en not_active Ceased
- 1995-10-24 ZA ZA959008A patent/ZA959008B/xx unknown
- 1995-10-24 IL IL11573895A patent/IL115738A/en not_active IP Right Cessation
- 1995-10-24 SK SK518-97A patent/SK283662B6/sk unknown
-
1997
- 1997-04-21 BG BG101427A patent/BG62877B1/bg unknown
- 1997-04-23 FI FI971742A patent/FI971742A0/fi unknown
- 1997-04-23 NO NO19971869A patent/NO314437B1/no unknown
- 1997-04-24 KR KR1019970702695A patent/KR970706827A/ko active Search and Examination
-
1999
- 1999-03-22 US US09/273,485 patent/US6143754A/en not_active Expired - Fee Related
Also Published As
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