DK0787002T3 - Kompetitive progesteronantagonister til behovsorienteret fertilitetskontrol hos kvinder - Google Patents

Kompetitive progesteronantagonister til behovsorienteret fertilitetskontrol hos kvinder

Info

Publication number
DK0787002T3
DK0787002T3 DK95937845T DK95937845T DK0787002T3 DK 0787002 T3 DK0787002 T3 DK 0787002T3 DK 95937845 T DK95937845 T DK 95937845T DK 95937845 T DK95937845 T DK 95937845T DK 0787002 T3 DK0787002 T3 DK 0787002T3
Authority
DK
Denmark
Prior art keywords
oriented
women
needs
progesterone antagonists
competitive progesterone
Prior art date
Application number
DK95937845T
Other languages
English (en)
Inventor
Kristof Chwalisz
Klaus Stoeckemann
Karin Schmidt-Gollwitzer
Walter Klemann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0787002T3 publication Critical patent/DK0787002T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK95937845T 1994-10-24 1995-10-24 Kompetitive progesteronantagonister til behovsorienteret fertilitetskontrol hos kvinder DK0787002T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4438820 1994-10-24
PCT/EP1995/004191 WO1996012494A1 (de) 1994-10-24 1995-10-24 Kompetitive progesteronantagonisten zur bedarfsorientierten weiblichen fertilitätskontrolle

Publications (1)

Publication Number Publication Date
DK0787002T3 true DK0787002T3 (da) 2007-04-10

Family

ID=6532105

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95937845T DK0787002T3 (da) 1994-10-24 1995-10-24 Kompetitive progesteronantagonister til behovsorienteret fertilitetskontrol hos kvinder

Country Status (25)

Country Link
US (1) US6143754A (da)
EP (1) EP0787002B1 (da)
JP (1) JPH10507461A (da)
KR (1) KR970706827A (da)
CN (1) CN1211087C (da)
AT (1) ATE347894T1 (da)
AU (1) AU707235B2 (da)
BG (1) BG62877B1 (da)
BR (1) BR9509478A (da)
CA (1) CA2203541A1 (da)
CZ (1) CZ290690B6 (da)
DE (1) DE59511071D1 (da)
DK (1) DK0787002T3 (da)
ES (1) ES2279515T3 (da)
FI (1) FI971742A0 (da)
HU (1) HU226566B1 (da)
IL (1) IL115738A (da)
NO (1) NO314437B1 (da)
NZ (1) NZ295365A (da)
PL (1) PL319869A1 (da)
PT (1) PT787002E (da)
RO (1) RO120606B1 (da)
SK (1) SK283662B6 (da)
WO (1) WO1996012494A1 (da)
ZA (1) ZA959008B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19745085A1 (de) * 1997-10-11 1999-04-15 Jenapharm Gmbh 11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
UA75339C2 (en) * 1999-08-31 2006-04-17 Schering Ag Use of mesoprogestins (progesterone receptor modulators) as pharmaceutical components for manufacture of medicament for hormone replacement therapy (hrt)
US7629334B1 (en) 1999-08-31 2009-12-08 Bayer Schering Pharma Aktiengesellschaft Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
HUP0202515A3 (en) * 1999-08-31 2004-06-28 Schering Ag Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives
DE102005050729A1 (de) * 2005-10-19 2007-04-26 Schering Ag Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption
JP2011507853A (ja) * 2007-12-20 2011-03-10 テバ ウィメンズ ヘルス インコーポレイテッド 緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ
ES2574999T3 (es) * 2009-04-14 2016-06-23 Laboratoire Hra-Pharma Método para la contracepción a demanda usando levonorgestrel o norgestrel
BRPI1014035A2 (pt) 2009-04-14 2016-04-12 Hra Pharma Lab método para contracepção.
AU2014270596A1 (en) 2013-05-23 2015-12-03 Bayer Pharma Aktiengesellschaft Pharmaceutical composition and the use thereof, and application regime of said pharmaceutical composition for on-demand contraception
KR20170084086A (ko) * 2014-11-17 2017-07-19 아르노 테라퓨틱스 인코포레이티드 오나프리스톤 연장-방출 조성물 및 방법
EP3353148A4 (en) 2015-09-25 2019-04-24 Context Biopharma Inc. PROCESS FOR THE PRODUCTION OF ONAPRISTONE INTERMEDIATE PRODUCTS
KR20180113988A (ko) * 2015-12-15 2018-10-17 컨텍스트 바이오파마 인코포레이티드 비정질 오나프리스톤 조성물 및 그 제조방법
WO2018102369A1 (en) 2016-11-30 2018-06-07 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439913A (en) * 1992-05-12 1995-08-08 Schering Aktiengesellschaft Contraception method using competitive progesterone antagonists and novel compounds useful therein

Also Published As

Publication number Publication date
IL115738A0 (en) 1996-01-19
BR9509478A (pt) 1997-09-30
EP0787002A1 (de) 1997-08-06
FI971742A (fi) 1997-04-23
EP0787002B1 (de) 2006-12-13
FI971742A0 (fi) 1997-04-23
NO971869L (no) 1997-04-23
CZ290690B6 (cs) 2002-09-11
CN1211087C (zh) 2005-07-20
AU707235B2 (en) 1999-07-08
HUT77518A (hu) 1998-05-28
CN1161649A (zh) 1997-10-08
NO971869D0 (no) 1997-04-23
BG62877B1 (bg) 2000-10-31
HU226566B1 (en) 2009-04-28
WO1996012494A1 (de) 1996-05-02
MX9703018A (es) 1997-10-31
ZA959008B (en) 1996-09-16
RO120606B1 (ro) 2006-05-30
NZ295365A (en) 1999-07-29
AU3869695A (en) 1996-05-15
NO314437B1 (no) 2003-03-24
PT787002E (pt) 2007-03-30
ES2279515T3 (es) 2007-08-16
JPH10507461A (ja) 1998-07-21
DE59511071D1 (de) 2007-01-25
BG101427A (en) 1997-11-28
KR970706827A (ko) 1997-12-01
CA2203541A1 (en) 1996-05-02
IL115738A (en) 2002-05-23
CZ118097A3 (en) 1997-07-16
SK283662B6 (sk) 2003-11-04
PL319869A1 (en) 1997-09-01
ATE347894T1 (de) 2007-01-15
US6143754A (en) 2000-11-07
SK51897A3 (en) 1997-09-10

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