SK282463B6 - Peptid schopný neutralizovať alebo modulovať produkciu antimyelínového bázického proteínu a farmaceutická kompozícia s jeho obsahom - Google Patents

Peptid schopný neutralizovať alebo modulovať produkciu antimyelínového bázického proteínu a farmaceutická kompozícia s jeho obsahom Download PDF

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Publication number
SK282463B6
SK282463B6 SK492-97A SK49297A SK282463B6 SK 282463 B6 SK282463 B6 SK 282463B6 SK 49297 A SK49297 A SK 49297A SK 282463 B6 SK282463 B6 SK 282463B6
Authority
SK
Slovakia
Prior art keywords
mbp
val
peptides
amino acid
peptide
Prior art date
Application number
SK492-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK49297A3 (en
Inventor
Kenneth G. Warren
Ingrid Catz
Original Assignee
The Governors Of The University Of Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Governors Of The University Of Alberta filed Critical The Governors Of The University Of Alberta
Publication of SK49297A3 publication Critical patent/SK49297A3/sk
Publication of SK282463B6 publication Critical patent/SK282463B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK492-97A 1994-10-21 1995-10-20 Peptid schopný neutralizovať alebo modulovať produkciu antimyelínového bázického proteínu a farmaceutická kompozícia s jeho obsahom SK282463B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/327,357 US5817629A (en) 1991-10-22 1994-10-21 Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
PCT/CA1995/000583 WO1996012731A1 (en) 1994-10-21 1995-10-20 Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients

Publications (2)

Publication Number Publication Date
SK49297A3 SK49297A3 (en) 1997-11-05
SK282463B6 true SK282463B6 (sk) 2002-02-05

Family

ID=23276218

Family Applications (1)

Application Number Title Priority Date Filing Date
SK492-97A SK282463B6 (sk) 1994-10-21 1995-10-20 Peptid schopný neutralizovať alebo modulovať produkciu antimyelínového bázického proteínu a farmaceutická kompozícia s jeho obsahom

Country Status (19)

Country Link
US (2) US5817629A (hu)
EP (1) EP0789709B1 (hu)
AT (1) ATE201415T1 (hu)
AU (1) AU713546B2 (hu)
CA (1) CA2203018A1 (hu)
CZ (1) CZ292454B6 (hu)
DE (1) DE69521055T2 (hu)
DK (1) DK0789709T3 (hu)
ES (1) ES2159322T3 (hu)
FI (1) FI120308B (hu)
HU (1) HU217633B (hu)
NO (1) NO321385B1 (hu)
NZ (1) NZ293910A (hu)
PL (1) PL182508B1 (hu)
RO (1) RO117096B1 (hu)
RU (1) RU2157815C2 (hu)
SK (1) SK282463B6 (hu)
UA (1) UA55375C2 (hu)
WO (1) WO1996012731A1 (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020111312A1 (en) * 1991-10-22 2002-08-15 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6252040B1 (en) 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6329499B1 (en) 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
US6251396B1 (en) * 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
CA2494338C (en) * 1997-04-04 2007-07-17 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
CN102784385B (zh) * 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
IL142535A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
IL142536A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Carriers for therapeutic preparations for treatment of t-cell mediated diseases
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
WO2002094864A2 (en) 2001-05-25 2002-11-28 Genset S.A. Human cdnas and proteins and uses thereof
JP2006502213A (ja) 2002-10-10 2006-01-19 イエダ リサーチ アンド デベロップメント カンパニー リミテッド 脂肪族アルコール類の塩基性エステルおよび抗炎症薬または免疫調整薬としての使用
ATE533500T1 (de) * 2003-02-14 2011-12-15 Provid Pharmaceuticals Inc Hemmer der antigenpräsentation über mhc-klasse-ii-moleküle und verwendungsverfahren dafür
EP2117301A4 (en) * 2007-02-26 2010-04-14 Yeda Res & Dev USE OF LONG-CHAINED ALCOHOL DERIVATIVES FOR THE TREATMENT OF CIRCULAR HAIR LOSS
WO2008106092A1 (en) * 2007-02-26 2008-09-04 Yeda Research And Development Co. Ltd. Enantiomers of amino-phenyl-acetic acid octadec- 9- (z) enyl ester, their salts and their uses
DK2211892T3 (da) 2007-10-31 2011-10-31 Apitope Technology Bristol Ltd Sammensætninger omfattende myelinbasiske proteinpeptider og medicinske anvendelser deraf
EP2229399A1 (en) * 2007-12-03 2010-09-22 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869054A (en) 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
DE3856566T2 (de) 1987-06-24 2004-06-24 Brigham And Women's Hospital, Boston Behandlung von Autoimmun-Erkrankungen durch orale Verabreichung von Autoantigenen
US5849298A (en) 1987-06-24 1998-12-15 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of bovine myelin
US5571500A (en) 1987-06-24 1996-11-05 Autoimmune, Inc. Treatment of autoimmune diseases through administration by inhalation of autoantigens
US5641474A (en) 1987-06-24 1997-06-24 Autoimmune, Inc. Prevention of autoimmune diseases by aerosol administration of autoantigens
US6039947A (en) 1987-06-24 2000-03-21 Autoimmune, Inc. Peptides derived from immunodominant epitopes of myelin basic protein
US5571499A (en) 1987-06-24 1996-11-05 Autoimmune, Inc. Treatment of autoimmune diseases by aerosol administration of autoantigens
US5645820A (en) 1987-06-24 1997-07-08 Autoimmune, Inc. Treatment of autoimmune diseases by aerosol administration of autoantigens
CA1340012C (en) * 1987-08-17 1998-08-25 Trustees Of Leland Stanford Jr. University Peptide determinant associated with immunity
US5858980A (en) 1990-03-30 1999-01-12 Autoimmune, Inc. Peptide fragments of myelin basic protein
IL97709A (en) 1990-03-30 2005-05-17 Brigham & Womens Hospital Use of an mbp peptide for the preparation of a medicament for the treatment of multiple sclerosis
CA2053799C (en) * 1991-10-22 2002-03-12 Kenneth G. Warren Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
ATE212358T1 (de) * 1992-04-09 2002-02-15 Autoimmune Inc Unterdrückung der proliferation von t-zellen mittels peptidfragmenten des basischen proteins aus myelin
WO1996028470A2 (en) 1995-03-09 1996-09-19 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
US5935577A (en) 1998-01-23 1999-08-10 Autoimmune Inc. Treatment of autoimmune disease using tolerization in combination with methotrexate

Also Published As

Publication number Publication date
RU2157815C2 (ru) 2000-10-20
AU3647895A (en) 1996-05-15
FI971662A0 (fi) 1997-04-18
RO117096B1 (ro) 2001-10-30
ES2159322T3 (es) 2001-10-01
DE69521055T2 (de) 2001-11-22
NO321385B1 (no) 2006-05-02
CZ116997A3 (en) 1997-10-15
DK0789709T3 (da) 2001-09-10
EP0789709B1 (en) 2001-05-23
US5817629A (en) 1998-10-06
NO971829L (no) 1997-06-23
CZ292454B6 (cs) 2003-09-17
NO971829D0 (no) 1997-04-21
AU713546B2 (en) 1999-12-02
FI120308B (fi) 2009-09-15
ATE201415T1 (de) 2001-06-15
UA55375C2 (uk) 2003-04-15
HUT76977A (hu) 1998-01-28
SK49297A3 (en) 1997-11-05
WO1996012731A1 (en) 1996-05-02
EP0789709A1 (en) 1997-08-20
US6258781B1 (en) 2001-07-10
HU217633B (hu) 2000-03-28
DE69521055D1 (de) 2001-06-28
NZ293910A (en) 1999-07-29
PL182508B1 (pl) 2002-01-31
CA2203018A1 (en) 1996-05-02
PL319835A1 (en) 1997-09-01
FI971662A (fi) 1997-06-17

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Publication Publication Date Title
SK282463B6 (sk) Peptid schopný neutralizovať alebo modulovať produkciu antimyelínového bázického proteínu a farmaceutická kompozícia s jeho obsahom
US7368429B2 (en) Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
EP0610446B1 (en) Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
EP1394178B1 (en) Method for the determination of the therapeutic activity of a MBP fragment
US20020147303A1 (en) Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20020111312A1 (en) Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
NZ513065A (en) Peptide fragments of MBP, their pharmaceutical compositions and their use in treating multiple sclerosis

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101020