DK0789709T3 - Peptidspecificitet af anti-myelin basisprotein og administrationen af myelin basisproteinpeptider til dissemineret sklerose patienter - Google Patents

Peptidspecificitet af anti-myelin basisprotein og administrationen af myelin basisproteinpeptider til dissemineret sklerose patienter

Info

Publication number
DK0789709T3
DK0789709T3 DK95934017T DK95934017T DK0789709T3 DK 0789709 T3 DK0789709 T3 DK 0789709T3 DK 95934017 T DK95934017 T DK 95934017T DK 95934017 T DK95934017 T DK 95934017T DK 0789709 T3 DK0789709 T3 DK 0789709T3
Authority
DK
Denmark
Prior art keywords
mbp
myelin basic
basic protein
administration
residues
Prior art date
Application number
DK95934017T
Other languages
English (en)
Inventor
Ingrid Catz
Kenneth G Warren
Original Assignee
Univ Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alberta filed Critical Univ Alberta
Application granted granted Critical
Publication of DK0789709T3 publication Critical patent/DK0789709T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK95934017T 1994-10-21 1995-10-20 Peptidspecificitet af anti-myelin basisprotein og administrationen af myelin basisproteinpeptider til dissemineret sklerose patienter DK0789709T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/327,357 US5817629A (en) 1991-10-22 1994-10-21 Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
PCT/CA1995/000583 WO1996012731A1 (en) 1994-10-21 1995-10-20 Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients

Publications (1)

Publication Number Publication Date
DK0789709T3 true DK0789709T3 (da) 2001-09-10

Family

ID=23276218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95934017T DK0789709T3 (da) 1994-10-21 1995-10-20 Peptidspecificitet af anti-myelin basisprotein og administrationen af myelin basisproteinpeptider til dissemineret sklerose patienter

Country Status (19)

Country Link
US (2) US5817629A (da)
EP (1) EP0789709B1 (da)
AT (1) ATE201415T1 (da)
AU (1) AU713546B2 (da)
CA (1) CA2203018A1 (da)
CZ (1) CZ292454B6 (da)
DE (1) DE69521055T2 (da)
DK (1) DK0789709T3 (da)
ES (1) ES2159322T3 (da)
FI (1) FI120308B (da)
HU (1) HU217633B (da)
NO (1) NO321385B1 (da)
NZ (1) NZ293910A (da)
PL (1) PL182508B1 (da)
RO (1) RO117096B1 (da)
RU (1) RU2157815C2 (da)
SK (1) SK282463B6 (da)
UA (1) UA55375C2 (da)
WO (1) WO1996012731A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6252040B1 (en) * 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20020111312A1 (en) * 1991-10-22 2002-08-15 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6251396B1 (en) * 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6329499B1 (en) 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
CA2494338C (en) * 1997-04-04 2007-07-17 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US20030191063A1 (en) * 2000-08-21 2003-10-09 Wraith David Cameron Peptide selection method
IL142536A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Carriers for therapeutic preparations for treatment of t-cell mediated diseases
IL142535A0 (en) * 2001-04-11 2002-03-10 Yeda Res & Dev Pharmaceutical compositions for the treatment of inflammation
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
EP1390497A2 (en) 2001-05-25 2004-02-25 Genset Human cdnas and proteins and uses thereof
NZ539106A (en) * 2002-10-10 2007-02-23 Yeda Res & Dev Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
WO2004073625A2 (en) * 2003-02-14 2004-09-02 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof
EP2117301A4 (en) * 2007-02-26 2010-04-14 Yeda Res & Dev USE OF LONG-CHAINED ALCOHOL DERIVATIVES FOR THE TREATMENT OF CIRCULAR HAIR LOSS
US7964751B2 (en) * 2007-02-26 2011-06-21 Yeda Research And Development Co. Ltd. Enantiomers of amino-phenyl-acetic acid octadec-9-(Z) enyl ester, their salts and their uses
AU2008320657B2 (en) 2007-10-31 2013-09-05 Worg Pharmaceuticals (Zhejiang) Co., Ltd. Composition
AU2008331789A1 (en) * 2007-12-03 2009-06-11 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by MHC Class II molecules and methods of use thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2512796B2 (ja) 1987-06-24 1996-07-03 オートイミュン・インコーポレイテッド 自己抗原の経口投与による自己免疫疾患の治療法
US6039947A (en) 1987-06-24 2000-03-21 Autoimmune, Inc. Peptides derived from immunodominant epitopes of myelin basic protein
US5571499A (en) 1987-06-24 1996-11-05 Autoimmune, Inc. Treatment of autoimmune diseases by aerosol administration of autoantigens
US5571500A (en) 1987-06-24 1996-11-05 Autoimmune, Inc. Treatment of autoimmune diseases through administration by inhalation of autoantigens
US5645820A (en) 1987-06-24 1997-07-08 Autoimmune, Inc. Treatment of autoimmune diseases by aerosol administration of autoantigens
US5641474A (en) 1987-06-24 1997-06-24 Autoimmune, Inc. Prevention of autoimmune diseases by aerosol administration of autoantigens
US5869054A (en) 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
US5849298A (en) 1987-06-24 1998-12-15 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of bovine myelin
CA1340012C (en) * 1987-08-17 1998-08-25 Trustees Of Leland Stanford Jr. University Peptide determinant associated with immunity
IL165071A (en) 1990-03-30 2008-06-05 Autoimmune Inc A peptide with the ability to stimulate a subset of T cells from multiple sclerosis patients
US5858980A (en) 1990-03-30 1999-01-12 Autoimmune, Inc. Peptide fragments of myelin basic protein
CA2053799C (en) * 1991-10-22 2002-03-12 Kenneth G. Warren Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
ES2172044T3 (es) * 1992-04-09 2002-09-16 Autoimmune Inc Supresion de la proliferacion de celulas t usando fragmentos peptidicos de proteina basica de mielina.
WO1996028470A2 (en) 1995-03-09 1996-09-19 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
US5935577A (en) 1998-01-23 1999-08-10 Autoimmune Inc. Treatment of autoimmune disease using tolerization in combination with methotrexate

Also Published As

Publication number Publication date
US6258781B1 (en) 2001-07-10
AU3647895A (en) 1996-05-15
SK49297A3 (en) 1997-11-05
UA55375C2 (uk) 2003-04-15
PL319835A1 (en) 1997-09-01
CA2203018A1 (en) 1996-05-02
DE69521055D1 (de) 2001-06-28
AU713546B2 (en) 1999-12-02
RU2157815C2 (ru) 2000-10-20
FI971662A0 (fi) 1997-04-18
PL182508B1 (pl) 2002-01-31
FI971662A (fi) 1997-06-17
ATE201415T1 (de) 2001-06-15
FI120308B (fi) 2009-09-15
HUT76977A (hu) 1998-01-28
CZ116997A3 (en) 1997-10-15
ES2159322T3 (es) 2001-10-01
HU217633B (hu) 2000-03-28
US5817629A (en) 1998-10-06
NO321385B1 (no) 2006-05-02
RO117096B1 (ro) 2001-10-30
NO971829L (no) 1997-06-23
EP0789709B1 (en) 2001-05-23
SK282463B6 (sk) 2002-02-05
DE69521055T2 (de) 2001-11-22
WO1996012731A1 (en) 1996-05-02
NZ293910A (en) 1999-07-29
NO971829D0 (no) 1997-04-21
CZ292454B6 (cs) 2003-09-17
EP0789709A1 (en) 1997-08-20

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