SK281085B6 - Deriváty 2-(aminometyl)-3,4,7,9-tetrahydro-2h-pyrán[2,3]-indol- -8-ónov, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Deriváty 2-(aminometyl)-3,4,7,9-tetrahydro-2h-pyrán[2,3]-indol- -8-ónov, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

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Publication number
SK281085B6
SK281085B6 SK1413-96A SK141396A SK281085B6 SK 281085 B6 SK281085 B6 SK 281085B6 SK 141396 A SK141396 A SK 141396A SK 281085 B6 SK281085 B6 SK 281085B6
Authority
SK
Slovakia
Prior art keywords
carbon atoms
tetrahydro
indol
alkyl
pharmaceutically acceptable
Prior art date
Application number
SK1413-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK141396A3 (en
Inventor
Richard Eric Mewshaw
Gary Paul Stack
Original Assignee
American Home Products Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corporation filed Critical American Home Products Corporation
Publication of SK141396A3 publication Critical patent/SK141396A3/sk
Publication of SK281085B6 publication Critical patent/SK281085B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1413-96A 1995-11-06 1996-10-31 Deriváty 2-(aminometyl)-3,4,7,9-tetrahydro-2h-pyrán[2,3]-indol- -8-ónov, farmaceutický prostriedok s ich obsahom a ich použitie SK281085B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US730795P 1995-11-06 1995-11-06

Publications (2)

Publication Number Publication Date
SK141396A3 SK141396A3 (en) 1997-05-07
SK281085B6 true SK281085B6 (sk) 2000-11-07

Family

ID=21725405

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1413-96A SK281085B6 (sk) 1995-11-06 1996-10-31 Deriváty 2-(aminometyl)-3,4,7,9-tetrahydro-2h-pyrán[2,3]-indol- -8-ónov, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (23)

Country Link
EP (1) EP0771801B1 (cs)
JP (1) JPH09169764A (cs)
KR (1) KR970027086A (cs)
CN (1) CN1083843C (cs)
AR (1) AR004523A1 (cs)
AT (1) ATE177102T1 (cs)
AU (1) AU701636B2 (cs)
BR (1) BR9605437B1 (cs)
CA (1) CA2189525C (cs)
CZ (1) CZ286649B6 (cs)
DE (1) DE69601611T2 (cs)
DK (1) DK0771801T3 (cs)
ES (1) ES2128145T3 (cs)
GR (1) GR3030132T3 (cs)
HK (1) HK1010104A1 (cs)
HU (1) HUP9603058A3 (cs)
IL (1) IL119483A (cs)
MX (1) MX9605369A (cs)
NO (1) NO964684L (cs)
NZ (1) NZ299680A (cs)
SK (1) SK281085B6 (cs)
TW (1) TW467914B (cs)
ZA (1) ZA969191B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264072A1 (en) * 1996-08-27 1998-03-05 American Home Products Corporation 4-aminoethoxy-indolone derivatives as dopamine d2 agonists
DE69722020T2 (de) * 1996-10-15 2004-01-22 Wyeth Azaheterocyclylmethyl-derivate von 2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-on
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
WO1998035946A1 (en) * 1997-02-18 1998-08-20 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists
US6541501B2 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541502B1 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
TW200811182A (en) 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314944A (en) 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
DE69524528T2 (de) * 1994-10-14 2002-08-01 Merck Patent Gmbh ZNS wirksames (R)-(-)-2-[5-(4-Fluorophenyl)-3-pyridylmethylaminomethyl]chroman

Also Published As

Publication number Publication date
CA2189525A1 (en) 1997-05-07
EP0771801A1 (en) 1997-05-07
ATE177102T1 (de) 1999-03-15
TW467914B (en) 2001-12-11
DK0771801T3 (da) 1999-09-27
EP0771801B1 (en) 1999-03-03
MX9605369A (es) 1997-05-31
BR9605437A (pt) 1998-08-04
AU701636B2 (en) 1999-02-04
CZ286649B6 (cs) 2000-05-17
JPH09169764A (ja) 1997-06-30
IL119483A (en) 1999-06-20
ES2128145T3 (es) 1999-05-01
HUP9603058A3 (en) 1998-12-28
CZ324096A3 (en) 1997-12-17
AU7055496A (en) 1997-05-15
HK1010104A1 (en) 1999-06-11
ZA969191B (en) 1998-04-30
AR004523A1 (es) 1998-12-16
HU9603058D0 (en) 1996-12-30
CN1151989A (zh) 1997-06-18
KR970027086A (ko) 1997-06-24
NO964684D0 (no) 1996-11-05
BR9605437B1 (pt) 2009-08-11
CA2189525C (en) 2006-04-25
SK141396A3 (en) 1997-05-07
GR3030132T3 (en) 1999-07-30
IL119483A0 (en) 1997-01-10
NO964684L (no) 1997-05-07
DE69601611D1 (de) 1999-04-08
DE69601611T2 (de) 1999-10-21
NZ299680A (en) 1998-05-27
HUP9603058A2 (en) 1997-05-28
CN1083843C (zh) 2002-05-01

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