IL119483A - 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them - Google Patents

2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them

Info

Publication number
IL119483A
IL119483A IL11948396A IL11948396A IL119483A IL 119483 A IL119483 A IL 119483A IL 11948396 A IL11948396 A IL 11948396A IL 11948396 A IL11948396 A IL 11948396A IL 119483 A IL119483 A IL 119483A
Authority
IL
Israel
Prior art keywords
pyrano
indol
aminomethyl
tetrahydro
ones
Prior art date
Application number
IL11948396A
Other languages
English (en)
Other versions
IL119483A0 (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL119483A0 publication Critical patent/IL119483A0/xx
Publication of IL119483A publication Critical patent/IL119483A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11948396A 1995-11-06 1996-10-24 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them IL119483A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US730795P 1995-11-06 1995-11-06

Publications (2)

Publication Number Publication Date
IL119483A0 IL119483A0 (en) 1997-01-10
IL119483A true IL119483A (en) 1999-06-20

Family

ID=21725405

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11948396A IL119483A (en) 1995-11-06 1996-10-24 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them

Country Status (22)

Country Link
EP (1) EP0771801B1 (cs)
JP (1) JPH09169764A (cs)
KR (1) KR970027086A (cs)
CN (1) CN1083843C (cs)
AR (1) AR004523A1 (cs)
AT (1) ATE177102T1 (cs)
AU (1) AU701636B2 (cs)
BR (1) BR9605437B1 (cs)
CA (1) CA2189525C (cs)
CZ (1) CZ286649B6 (cs)
DE (1) DE69601611T2 (cs)
DK (1) DK0771801T3 (cs)
ES (1) ES2128145T3 (cs)
GR (1) GR3030132T3 (cs)
HU (1) HUP9603058A3 (cs)
IL (1) IL119483A (cs)
MX (1) MX9605369A (cs)
NO (1) NO964684L (cs)
NZ (1) NZ299680A (cs)
SK (1) SK281085B6 (cs)
TW (1) TW467914B (cs)
ZA (1) ZA969191B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000035822A (ko) * 1996-08-27 2000-06-26 이곤 이 버그 도파민 디2 효능제로서의 4-아미노에톡시-인돌론 유도체
JP2001502327A (ja) * 1996-10-15 2001-02-20 アメリカン・ホーム・プロダクツ・コーポレイション 2,3,8,9―テトラヒドロ―7H―1,4―ジオキシノ[2,3―e]インドール―8―オンのアザヘテロサイクリルメチル誘導体
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
CN1138761C (zh) * 1997-02-18 2004-02-18 惠氏公司 4-氨基烷氧基-1,3-二氢苯并咪唑-2-酮衍生物、它们的制备方法以及它们作为多巴胺自身受体(d2)激动剂的用途
US6541502B1 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
TW200811182A (en) 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314944A (en) 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
EP1123933A1 (en) * 1994-10-14 2001-08-16 MERCK PATENT GmbH 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chromane as CNS active agent

Also Published As

Publication number Publication date
CZ286649B6 (cs) 2000-05-17
HK1010104A1 (en) 1999-06-11
AU701636B2 (en) 1999-02-04
CA2189525C (en) 2006-04-25
GR3030132T3 (en) 1999-07-30
ES2128145T3 (es) 1999-05-01
ZA969191B (en) 1998-04-30
NZ299680A (en) 1998-05-27
HUP9603058A2 (en) 1997-05-28
SK141396A3 (en) 1997-05-07
AU7055496A (en) 1997-05-15
HU9603058D0 (en) 1996-12-30
ATE177102T1 (de) 1999-03-15
SK281085B6 (sk) 2000-11-07
IL119483A0 (en) 1997-01-10
CA2189525A1 (en) 1997-05-07
AR004523A1 (es) 1998-12-16
MX9605369A (es) 1997-05-31
BR9605437A (pt) 1998-08-04
BR9605437B1 (pt) 2009-08-11
JPH09169764A (ja) 1997-06-30
DE69601611T2 (de) 1999-10-21
DE69601611D1 (de) 1999-04-08
CN1151989A (zh) 1997-06-18
CN1083843C (zh) 2002-05-01
HUP9603058A3 (en) 1998-12-28
EP0771801B1 (en) 1999-03-03
KR970027086A (ko) 1997-06-24
CZ324096A3 (en) 1997-12-17
DK0771801T3 (da) 1999-09-27
EP0771801A1 (en) 1997-05-07
NO964684D0 (no) 1996-11-05
TW467914B (en) 2001-12-11
NO964684L (no) 1997-05-07

Similar Documents

Publication Publication Date Title
NZ304982A (en) Pyridinyloxy- or pyridinylamino-acetamide derivatives; pharmaceutical compositions
HU9601698D0 (en) Pharmaceutical composition
IL109316A0 (en) 1, 5-benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
IL118426A0 (en) Pharmaceutical composition containing 1,3-bis-triazolyl-2- propanol derivative
IL122705A (en) 2-(4-Susbstituted)-benzylamino-2-methyl-propanamide derivatives their preparation and pharmaceutical compositions containing them
HUP9801386A3 (en) Indazolecarboxamide derivatives, preparation thereof and pharmaceutical compositions containing them
ZA962214B (en) Pharmaceutical composition
GB9519667D0 (en) Pharmaceutical composition
IL110366A0 (en) 1,5-Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
ZA963590B (en) Pharmaceutical composition
IL119483A (en) 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
GB9525194D0 (en) Pharmaceutical composition
ZA961051B (en) Pharmaceutical composition
HUP9602774A2 (en) Benzoxazepine derivatives, pharmaceutical compositions containing them and intermediates
ZA964193B (en) Pharmaceutical composition
IL124415A (en) N, n'-bridged bisindolylmaleimides, their preparation and pharmaceutical compositions containing them
HUP9802291A3 (en) Penicillaminamide derivatives and pharmaceutical compositions containing them
HUP0002659A3 (en) Benzo-5,6-cyclohepta[1,2-b]pyridine derivatives, pharmaceutical compositions containing them and their use
IL120469A0 (en) 1, 25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives their preparation and pharmaceutical compositions containing them
HUP9902041A3 (en) New quuinoxalindione derivatives, their preparation and pharmaceutical compositions containing them
ZA968616B (en) Pharmaceutical composition
ZA963591B (en) Pharmaceutical composition
HUP9802072A3 (en) Benzothiopyranoindazole derivatives and pharmaceutical compositions containing them
ZA95736B (en) Pharmaceutical composition
HUP9700688A3 (en) New 2,3-benzodiazepine derivatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
RH1 Patent not in force