NZ299680A - 2-[4-(optionally substituted)-benzylamino- methyl]-3,4,7,9-tetrahydro-2h-pyrano[2,3-e]indol-8-one derivatives; medicaments - Google Patents

2-[4-(optionally substituted)-benzylamino- methyl]-3,4,7,9-tetrahydro-2h-pyrano[2,3-e]indol-8-one derivatives; medicaments

Info

Publication number
NZ299680A
NZ299680A NZ299680A NZ29968096A NZ299680A NZ 299680 A NZ299680 A NZ 299680A NZ 299680 A NZ299680 A NZ 299680A NZ 29968096 A NZ29968096 A NZ 29968096A NZ 299680 A NZ299680 A NZ 299680A
Authority
NZ
New Zealand
Prior art keywords
carbon atoms
compound
methyl
pharmaceutically acceptable
pyrano
Prior art date
Application number
NZ299680A
Other languages
English (en)
Inventor
Gary Paul Stack
Richard Eric Mewshaw
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of NZ299680A publication Critical patent/NZ299680A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ299680A 1995-11-06 1996-11-01 2-[4-(optionally substituted)-benzylamino- methyl]-3,4,7,9-tetrahydro-2h-pyrano[2,3-e]indol-8-one derivatives; medicaments NZ299680A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US730795P 1995-11-06 1995-11-06

Publications (1)

Publication Number Publication Date
NZ299680A true NZ299680A (en) 1998-05-27

Family

ID=21725405

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ299680A NZ299680A (en) 1995-11-06 1996-11-01 2-[4-(optionally substituted)-benzylamino- methyl]-3,4,7,9-tetrahydro-2h-pyrano[2,3-e]indol-8-one derivatives; medicaments

Country Status (23)

Country Link
EP (1) EP0771801B1 (cs)
JP (1) JPH09169764A (cs)
KR (1) KR970027086A (cs)
CN (1) CN1083843C (cs)
AR (1) AR004523A1 (cs)
AT (1) ATE177102T1 (cs)
AU (1) AU701636B2 (cs)
BR (1) BR9605437B1 (cs)
CA (1) CA2189525C (cs)
CZ (1) CZ286649B6 (cs)
DE (1) DE69601611T2 (cs)
DK (1) DK0771801T3 (cs)
ES (1) ES2128145T3 (cs)
GR (1) GR3030132T3 (cs)
HK (1) HK1010104A1 (cs)
HU (1) HUP9603058A3 (cs)
IL (1) IL119483A (cs)
MX (1) MX9605369A (cs)
NO (1) NO964684L (cs)
NZ (1) NZ299680A (cs)
SK (1) SK281085B6 (cs)
TW (1) TW467914B (cs)
ZA (1) ZA969191B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264072A1 (en) * 1996-08-27 1998-03-05 American Home Products Corporation 4-aminoethoxy-indolone derivatives as dopamine d2 agonists
DE69722020T2 (de) * 1996-10-15 2004-01-22 Wyeth Azaheterocyclylmethyl-derivate von 2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-on
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
WO1998035946A1 (en) * 1997-02-18 1998-08-20 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists
US6541501B2 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541502B1 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
TW200811182A (en) 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314944A (en) 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
DE69524528T2 (de) * 1994-10-14 2002-08-01 Merck Patent Gmbh ZNS wirksames (R)-(-)-2-[5-(4-Fluorophenyl)-3-pyridylmethylaminomethyl]chroman

Also Published As

Publication number Publication date
CA2189525A1 (en) 1997-05-07
EP0771801A1 (en) 1997-05-07
ATE177102T1 (de) 1999-03-15
TW467914B (en) 2001-12-11
DK0771801T3 (da) 1999-09-27
EP0771801B1 (en) 1999-03-03
MX9605369A (es) 1997-05-31
BR9605437A (pt) 1998-08-04
AU701636B2 (en) 1999-02-04
CZ286649B6 (cs) 2000-05-17
JPH09169764A (ja) 1997-06-30
IL119483A (en) 1999-06-20
ES2128145T3 (es) 1999-05-01
HUP9603058A3 (en) 1998-12-28
CZ324096A3 (en) 1997-12-17
AU7055496A (en) 1997-05-15
HK1010104A1 (en) 1999-06-11
ZA969191B (en) 1998-04-30
AR004523A1 (es) 1998-12-16
HU9603058D0 (en) 1996-12-30
CN1151989A (zh) 1997-06-18
KR970027086A (ko) 1997-06-24
NO964684D0 (no) 1996-11-05
BR9605437B1 (pt) 2009-08-11
CA2189525C (en) 2006-04-25
SK141396A3 (en) 1997-05-07
GR3030132T3 (en) 1999-07-30
SK281085B6 (sk) 2000-11-07
IL119483A0 (en) 1997-01-10
NO964684L (no) 1997-05-07
DE69601611D1 (de) 1999-04-08
DE69601611T2 (de) 1999-10-21
HUP9603058A2 (en) 1997-05-28
CN1083843C (zh) 2002-05-01

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