SK2197A3 - Derivatives of azolones, manufacturing process thereof, pharmauceutical compositions on their base and process for producing them - Google Patents

Derivatives of azolones, manufacturing process thereof, pharmauceutical compositions on their base and process for producing them Download PDF

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Publication number
SK2197A3
SK2197A3 SK21-97A SK2197A SK2197A3 SK 2197 A3 SK2197 A3 SK 2197A3 SK 2197 A SK2197 A SK 2197A SK 2197 A3 SK2197 A3 SK 2197A3
Authority
SK
Slovakia
Prior art keywords
formula
alkyl
optionally substituted
pyridyl
piperazinyl
Prior art date
Application number
SK21-97A
Other languages
English (en)
Slovak (sk)
Inventor
Jan Heeres
Raymond A Stokbroekx
Marc Willems
Robert J M Hendrickx
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SK2197A3 publication Critical patent/SK2197A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerization Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
SK21-97A 1994-07-12 1995-07-05 Derivatives of azolones, manufacturing process thereof, pharmauceutical compositions on their base and process for producing them SK2197A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94202018 1994-07-12
PCT/EP1995/002616 WO1996001821A1 (en) 1994-07-12 1995-07-05 Anti-helicobacter heterocyclic derivatives of azolones

Publications (1)

Publication Number Publication Date
SK2197A3 true SK2197A3 (en) 1997-11-05

Family

ID=8217031

Family Applications (1)

Application Number Title Priority Date Filing Date
SK21-97A SK2197A3 (en) 1994-07-12 1995-07-05 Derivatives of azolones, manufacturing process thereof, pharmauceutical compositions on their base and process for producing them

Country Status (20)

Country Link
US (1) US5607932A (de)
EP (1) EP0770073A1 (de)
JP (1) JPH10502383A (de)
CN (1) CN1067999C (de)
AU (1) AU684986B2 (de)
BR (1) BR9508380A (de)
CA (1) CA2194563A1 (de)
CZ (1) CZ2697A3 (de)
FI (1) FI970110A0 (de)
HU (1) HUT76641A (de)
IL (1) IL114534A (de)
MX (1) MX9700338A (de)
MY (1) MY131785A (de)
NO (1) NO310289B1 (de)
NZ (1) NZ290116A (de)
PL (1) PL318142A1 (de)
RU (1) RU2152940C1 (de)
SK (1) SK2197A3 (de)
WO (1) WO1996001821A1 (de)
ZA (1) ZA955753B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100411190B1 (ko) * 1995-12-26 2004-03-26 에스케이케미칼주식회사 에틸렌글리콜의회수방법
US6169102B1 (en) 1996-06-25 2001-01-02 Takeda Chemical Industries, Ltd. Oxazolone derivatives and their use as anti-Helicobacter pylori agent
CA2248784A1 (en) * 1996-06-25 1997-12-31 Takeda Chemical Industries, Ltd. Oxazolone derivatives and their use
EP1799668A1 (de) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterozyklische derivate und ihre verwendung als stearoyl-coa-desaturase-mediatoren
AR051092A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa
AU2005329423A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515500A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados piridazina para inibição de estearoil-coa-desaturase
JP5043668B2 (ja) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
BRPI0515489A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados heterocìclicos e sua utilização como inibidores de estearoil-coa desaturase
US7919496B2 (en) 2004-09-20 2011-04-05 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
CN101208089A (zh) 2005-06-03 2008-06-25 泽农医药公司 氨基噻唑衍生物作为人硬酯酰-CoA去饱和酶抑制剂
PE20110136A1 (es) * 2008-06-27 2011-03-17 Novartis Ag Compuestos organicos
WO2013175215A1 (en) 2012-05-22 2013-11-28 Autifony Therapeutics Limited Triazoles as kv3 inhibitors
CN109153663B (zh) * 2016-05-27 2021-08-13 百时美施贵宝公司 作为rock抑制剂的三唑酮类化合物和四唑酮类化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
TW279864B (de) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv

Also Published As

Publication number Publication date
MY131785A (en) 2007-08-30
WO1996001821A1 (en) 1996-01-25
NZ290116A (en) 1997-11-24
CA2194563A1 (en) 1996-01-25
EP0770073A1 (de) 1997-05-02
HUT76641A (en) 1997-10-28
MX9700338A (es) 1997-05-31
PL318142A1 (en) 1997-05-12
AU3075595A (en) 1996-02-09
HU9700077D0 (en) 1997-02-28
NO970086L (no) 1997-03-10
RU2152940C1 (ru) 2000-07-20
US5607932A (en) 1997-03-04
FI970110A (fi) 1997-01-10
IL114534A0 (en) 1995-11-27
CN1067999C (zh) 2001-07-04
CZ2697A3 (en) 1997-09-17
AU684986B2 (en) 1998-01-08
CN1152310A (zh) 1997-06-18
NO310289B1 (no) 2001-06-18
FI970110A0 (fi) 1997-01-10
NO970086D0 (no) 1997-01-09
BR9508380A (pt) 1997-12-23
IL114534A (en) 1999-08-17
ZA955753B (en) 1997-01-11
JPH10502383A (ja) 1998-03-03

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