SK181498A3 - Method for producing therapeutic dna, application of plasmid dna for producing a pharmaceutical composition - Google Patents

Method for producing therapeutic dna, application of plasmid dna for producing a pharmaceutical composition Download PDF

Info

Publication number
SK181498A3
SK181498A3 SK1814-98A SK181498A SK181498A3 SK 181498 A3 SK181498 A3 SK 181498A3 SK 181498 A SK181498 A SK 181498A SK 181498 A3 SK181498 A3 SK 181498A3
Authority
SK
Slovakia
Prior art keywords
dna
plasmid
methylated
dinucleotides
plasmid dna
Prior art date
Application number
SK1814-98A
Other languages
English (en)
Slovak (sk)
Inventor
Joel Crouzet
Beatrice Cameron
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of SK181498A3 publication Critical patent/SK181498A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK1814-98A 1996-07-04 1997-06-24 Method for producing therapeutic dna, application of plasmid dna for producing a pharmaceutical composition SK181498A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9608327A FR2750704B1 (fr) 1996-07-04 1996-07-04 Procede de production d'adn therapeutique
PCT/FR1997/001116 WO1998001540A1 (fr) 1996-07-04 1997-06-24 Procede de production d'adn therapeutique

Publications (1)

Publication Number Publication Date
SK181498A3 true SK181498A3 (en) 1999-07-12

Family

ID=9493705

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1814-98A SK181498A3 (en) 1996-07-04 1997-06-24 Method for producing therapeutic dna, application of plasmid dna for producing a pharmaceutical composition

Country Status (14)

Country Link
US (2) US6410273B1 (de)
EP (1) EP0914418A1 (de)
JP (1) JP2000514293A (de)
KR (1) KR20000022488A (de)
AU (1) AU722909B2 (de)
BR (1) BR9710173A (de)
CA (1) CA2258792A1 (de)
CZ (1) CZ438298A3 (de)
FR (1) FR2750704B1 (de)
IL (1) IL127620A0 (de)
NO (1) NO986177L (de)
SK (1) SK181498A3 (de)
WO (1) WO1998001540A1 (de)
ZA (1) ZA975959B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026468B2 (en) 1996-07-19 2006-04-11 Valentis, Inc. Process and equipment for plasmid purification
US7807822B2 (en) 1996-08-01 2010-10-05 Robert Bridenbaugh Methods for purifying nucleic acids
US7026155B2 (en) * 1999-02-02 2006-04-11 Regents Of The University Of California Method of reducing bacterial proliferation
ES2252293T3 (es) * 2000-09-18 2006-05-16 Genzyme Corporation Vectores de expresion que contienene promotores hibridos de ubiquitina.
GB0025913D0 (en) * 2000-10-23 2000-12-06 Guldberg Per Materials and methods relating to nucleic acid amplification and profiling
US20030152950A1 (en) * 2001-06-27 2003-08-14 Garner Harold R. Identification of chemically modified polymers
US6989265B2 (en) * 2002-01-23 2006-01-24 Wisconsin Alumni Research Foundation Bacteria with reduced genome
US8765408B2 (en) 2002-01-23 2014-07-01 Wisconsin Alumni Research Foundation Prophage element-free bacteria
US20060270043A1 (en) * 2002-01-23 2006-11-30 Blattner Frederick R Bacteria with reduced genome
US8119365B2 (en) * 2002-01-23 2012-02-21 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US8039243B2 (en) * 2002-01-23 2011-10-18 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US7303906B2 (en) 2002-09-06 2007-12-04 Wisconsin Alumni Research Foundation Competent bacteria
US20090191218A1 (en) 2005-05-11 2009-07-30 Fengchun Li DNA Vaccines And Methods For The Prevention Of Transplantation Rejection
ES2348701T3 (es) * 2005-05-11 2010-12-10 Loma Linda University Composiciones y mã‰todos para prevenir y tratar trastornos inflamatorios de mediaciã“n inmune.
EP3756674A1 (de) * 2006-09-28 2020-12-30 Loma Linda University Durch apoptotische zellen vermittelte transfektion von säugetierzellen mit interferierender rna
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
WO2013044177A2 (en) 2011-09-23 2013-03-28 Loma Linda University Bacterial strains expressing methylase genes and uses thereof
US11680273B2 (en) 2011-09-23 2023-06-20 Loma Linda University Treatment of autoimmune diseases
EP3921416A1 (de) * 2019-02-06 2021-12-15 Fred Hutchinson Cancer Research Center Minicircle-produzierende manipulierte bakterien zur differentiellen methylierung von nukleinsäuren darin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693622A (en) 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5491060A (en) * 1989-05-01 1996-02-13 The University Of Maryland Mutant strain of E. coli for detection of methyltransferase clones
DE69019890T2 (de) * 1989-08-07 1996-02-08 Yissum Res Dev Co Verfahren zur Produktion von der Spiroplasma sp. DNA Methylase.
US5405760A (en) * 1992-04-30 1995-04-11 New England Biolabs, Inc. Process for producing recombinant McrBC endonuclease and cleavage of methylated DNA
US5470740A (en) * 1993-11-04 1995-11-28 Life Technologies, Inc. Cloned NsiI restriction-modification system
US5587305A (en) * 1993-12-06 1996-12-24 The United States Of America As Represented By The Department Of Agriculture Pasteurella haemolytica transformants
FR2714830B1 (fr) 1994-01-10 1996-03-22 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
EP1167377B2 (de) * 1994-07-15 2012-08-08 University of Iowa Research Foundation Immunomodulatorische Oligonukleotide
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
FR2739292B1 (fr) 1995-09-28 1997-10-31 Rhone Poulenc Rorer Sa Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations
FR2741066B1 (fr) 1995-11-14 1997-12-12 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
FR2754272B1 (fr) 1996-10-08 1998-11-13 Rhone Poulenc Rorer Sa Procede de preparation de compositions pour le transfert d'acides nucleiques
US6060245A (en) 1996-12-13 2000-05-09 Stratagene Methods and adaptors for generating specific nucleic acid populations

Also Published As

Publication number Publication date
BR9710173A (pt) 1999-08-10
EP0914418A1 (de) 1999-05-12
CA2258792A1 (fr) 1998-01-15
WO1998001540A1 (fr) 1998-01-15
FR2750704A1 (fr) 1998-01-09
JP2000514293A (ja) 2000-10-31
AU722909B2 (en) 2000-08-17
US20020187527A1 (en) 2002-12-12
KR20000022488A (ko) 2000-04-25
AU3447597A (en) 1998-02-02
US6410273B1 (en) 2002-06-25
CZ438298A3 (cs) 1999-04-14
NO986177L (no) 1999-02-15
ZA975959B (en) 1998-01-30
FR2750704B1 (fr) 1998-09-25
NO986177D0 (no) 1998-12-29
IL127620A0 (en) 1999-10-28

Similar Documents

Publication Publication Date Title
SK181498A3 (en) Method for producing therapeutic dna, application of plasmid dna for producing a pharmaceutical composition
Mayrhofer et al. Use of minicircle plasmids for gene therapy
JP4756014B2 (ja) 条件複製起点をもつ環状ｄｎａ分子、それらの製造方法、及び、遺伝子治療におけるそれらの使用
JPH11500618A (ja) Ｄｎａ分子、その製造及び遺伝子治療における使用
Mairhofer et al. Rational vector design for efficient non-viral gene delivery: challenges facing the use of plasmid DNA
FI120046B (fi) Menetelmä yhdistelmä-DNA-adenovirusgenomin valmistamiseksi
WO2001075092A2 (en) CpG REDUCED PLASMIDS AND VIRAL VECTORS
MX2007003214A (es) Formulaciones liquidas estables de adn plasmidico.
CN112154208A (zh) 产生改进的病毒和非病毒纳米质粒载体
CN115768487A (zh) 用于面肩肱型肌营养不良症的crispr抑制
Tan et al. Overcoming the inflammatory toxicity of cationic gene vectors
Schakowski et al. Minimal size MIDGE vectors improve transgene expression in vivo
US20060183703A1 (en) Circular expression construct for gene therapeutic applications
MXPA98010328A (en) Terapeut dna production procedure
US6323003B1 (en) Compositions and methods for activating genes of interest
US20170096679A1 (en) Eukaryotic expression vectors resistant to transgene silencing
US9816077B2 (en) Use of integrase for targeted gene expression
Tolmachov et al. Minimized, CpG‐Depleted, and Methylated DNA Vectors: Towards Perfection in Nonviral Gene Therapy
Bigey et al. Optimization of plasmid backbone for gene expression in mammalian cells