FR2754272B1 - Procede de preparation de compositions pour le transfert d'acides nucleiques - Google Patents

Procede de preparation de compositions pour le transfert d'acides nucleiques

Info

Publication number
FR2754272B1
FR2754272B1 FR9612259A FR9612259A FR2754272B1 FR 2754272 B1 FR2754272 B1 FR 2754272B1 FR 9612259 A FR9612259 A FR 9612259A FR 9612259 A FR9612259 A FR 9612259A FR 2754272 B1 FR2754272 B1 FR 2754272B1
Authority
FR
France
Prior art keywords
compositions
preparation
nucleic acids
transferring nucleic
transferring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9612259A
Other languages
English (en)
Other versions
FR2754272A1 (fr
Inventor
Joel Vacus
Tsiala Boukhnikachvili
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9612259A priority Critical patent/FR2754272B1/fr
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to PCT/FR1997/001747 priority patent/WO1998015639A1/fr
Priority to CZ991192A priority patent/CZ119299A3/cs
Priority to HU9904579A priority patent/HUP9904579A3/hu
Priority to SK431-99A priority patent/SK43199A3/sk
Priority to BR9712210-6A priority patent/BR9712210A/pt
Priority to KR1019990703006A priority patent/KR20000048958A/ko
Priority to AU45591/97A priority patent/AU723371B2/en
Priority to EP97943929A priority patent/EP0948638A1/fr
Priority to CA002267187A priority patent/CA2267187A1/fr
Priority to IL12933697A priority patent/IL129336A0/xx
Priority to JP10517234A priority patent/JP2001501641A/ja
Priority to US09/269,515 priority patent/US6156338A/en
Priority to ZA9709031A priority patent/ZA979031B/xx
Publication of FR2754272A1 publication Critical patent/FR2754272A1/fr
Application granted granted Critical
Publication of FR2754272B1 publication Critical patent/FR2754272B1/fr
Priority to NO991383A priority patent/NO991383D0/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
FR9612259A 1996-10-08 1996-10-08 Procede de preparation de compositions pour le transfert d'acides nucleiques Expired - Fee Related FR2754272B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR9612259A FR2754272B1 (fr) 1996-10-08 1996-10-08 Procede de preparation de compositions pour le transfert d'acides nucleiques
IL12933697A IL129336A0 (en) 1996-10-08 1997-10-03 Method for preparing compositions for transferring nucleic acids
HU9904579A HUP9904579A3 (en) 1996-10-08 1997-10-03 Method for preparing compositions for transferring nucleic acids
SK431-99A SK43199A3 (en) 1996-10-08 1997-10-03 Method for preparing compositions for transferring nucleic acids
BR9712210-6A BR9712210A (pt) 1996-10-08 1997-10-03 Processos de preparação de uma composição para a transferência de ácidos nucléicos e para a transferência de ácido nucléico em células in vitro ou ex vivo, e, composição para a transferência de ácidos nucléicos.
KR1019990703006A KR20000048958A (ko) 1996-10-08 1997-10-03 핵산 전달용 조성물의 제조방법
AU45591/97A AU723371B2 (en) 1996-10-08 1997-10-03 Process for preparing compositions for the transfer of nucleic acids
EP97943929A EP0948638A1 (fr) 1996-10-08 1997-10-03 Procede de preparation de compositions pour le transfert d'acides nucleiques
PCT/FR1997/001747 WO1998015639A1 (fr) 1996-10-08 1997-10-03 Procede de preparation de compositions pour le transfert d'acides nucleiques
CZ991192A CZ119299A3 (cs) 1996-10-08 1997-10-03 Způsob přípravy prostředku pro přenos nukleových kyselin
JP10517234A JP2001501641A (ja) 1996-10-08 1997-10-03 核酸導入用組成物の製造方法
US09/269,515 US6156338A (en) 1996-10-08 1997-10-03 Method for preparing compositions for transferring nucleic acids
CA002267187A CA2267187A1 (fr) 1996-10-08 1997-10-03 Procede de preparation de compositions pour le transfert d'acides nucleiques
ZA9709031A ZA979031B (en) 1996-10-08 1997-10-08 Process for preparing compositions for the transfer of nucleic acids.
NO991383A NO991383D0 (no) 1996-10-08 1999-03-22 FremgangsmÕte for fremstilling av preparater for overf°ring av nukleinsyrer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9612259A FR2754272B1 (fr) 1996-10-08 1996-10-08 Procede de preparation de compositions pour le transfert d'acides nucleiques

Publications (2)

Publication Number Publication Date
FR2754272A1 FR2754272A1 (fr) 1998-04-10
FR2754272B1 true FR2754272B1 (fr) 1998-11-13

Family

ID=9496468

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9612259A Expired - Fee Related FR2754272B1 (fr) 1996-10-08 1996-10-08 Procede de preparation de compositions pour le transfert d'acides nucleiques

Country Status (15)

Country Link
US (1) US6156338A (fr)
EP (1) EP0948638A1 (fr)
JP (1) JP2001501641A (fr)
KR (1) KR20000048958A (fr)
AU (1) AU723371B2 (fr)
BR (1) BR9712210A (fr)
CA (1) CA2267187A1 (fr)
CZ (1) CZ119299A3 (fr)
FR (1) FR2754272B1 (fr)
HU (1) HUP9904579A3 (fr)
IL (1) IL129336A0 (fr)
NO (1) NO991383D0 (fr)
SK (1) SK43199A3 (fr)
WO (1) WO1998015639A1 (fr)
ZA (1) ZA979031B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2750704B1 (fr) 1996-07-04 1998-09-25 Rhone Poulenc Rorer Sa Procede de production d'adn therapeutique
US6479288B1 (en) 1998-02-17 2002-11-12 University Of Wales College Of Medicine Method and apparatus for introducing substances into the cell plasma membrane and/or cytosol
CN1254234C (zh) * 2000-06-09 2006-05-03 莱古伦公司 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中
JP2005529959A (ja) * 2002-06-14 2005-10-06 マイラス コーポレイション 細胞へのポリヌクレオチドの伝達をするための新規な方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873089A (en) * 1985-07-12 1989-10-10 Cornell Research Foundation Inc., Cornell University Proteoliposomes as drug carriers
JPS63277618A (ja) * 1987-03-31 1988-11-15 Noebia:Kk リポソ−ムの製造方法
CA1330199C (fr) * 1987-12-22 1994-06-14 Thomas D. Madden Vesiculation spontanee de liposomes multilamellaires
FR2714830B1 (fr) * 1994-01-10 1996-03-22 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2727679B1 (fr) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques

Also Published As

Publication number Publication date
US6156338A (en) 2000-12-05
KR20000048958A (ko) 2000-07-25
HUP9904579A2 (hu) 2000-05-28
ZA979031B (en) 1998-04-23
JP2001501641A (ja) 2001-02-06
NO991383L (no) 1999-03-22
CZ119299A3 (cs) 1999-07-14
HUP9904579A3 (en) 2001-06-28
FR2754272A1 (fr) 1998-04-10
BR9712210A (pt) 1999-08-31
NO991383D0 (no) 1999-03-22
IL129336A0 (en) 2000-02-17
WO1998015639A1 (fr) 1998-04-16
AU723371B2 (en) 2000-08-24
SK43199A3 (en) 2000-04-10
CA2267187A1 (fr) 1998-04-16
EP0948638A1 (fr) 1999-10-13
AU4559197A (en) 1998-05-05

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Legal Events

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ST Notification of lapse