CA1330199C - Vesiculation spontanee de liposomes multilamellaires - Google Patents

Vesiculation spontanee de liposomes multilamellaires

Info

Publication number
CA1330199C
CA1330199C CA000586752A CA586752A CA1330199C CA 1330199 C CA1330199 C CA 1330199C CA 000586752 A CA000586752 A CA 000586752A CA 586752 A CA586752 A CA 586752A CA 1330199 C CA1330199 C CA 1330199C
Authority
CA
Canada
Prior art keywords
liposomes
vesicles
lipid
incubated
vesiculation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000586752A
Other languages
English (en)
Inventor
Thomas D. Madden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/136,267 external-priority patent/US4963297A/en
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of CA1330199C publication Critical patent/CA1330199C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000586752A 1987-12-22 1988-12-22 Vesiculation spontanee de liposomes multilamellaires Expired - Fee Related CA1330199C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/136,267 US4963297A (en) 1987-12-22 1987-12-22 Spontaneous vesticulation of multilamellar liposomes
US136,267 1987-12-22
US23670088A 1988-08-25 1988-08-25
US236,700 1988-08-25

Publications (1)

Publication Number Publication Date
CA1330199C true CA1330199C (fr) 1994-06-14

Family

ID=26834174

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000586752A Expired - Fee Related CA1330199C (fr) 1987-12-22 1988-12-22 Vesiculation spontanee de liposomes multilamellaires

Country Status (4)

Country Link
EP (1) EP0393145A4 (fr)
JP (1) JPH03501732A (fr)
CA (1) CA1330199C (fr)
WO (1) WO1989005636A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107153A1 (de) * 1991-03-06 1992-09-10 Gregor Cevc Praeparat zur wirkstoffapplikation in kleinsttroepfchenform
DE4107152C2 (de) * 1991-03-06 1994-03-24 Gregor Cevc Präparate zur nichtinvasiven Verabreichung von Antidiabetica
IS1685B (is) * 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
FR2754272B1 (fr) * 1996-10-08 1998-11-13 Rhone Poulenc Rorer Sa Procede de preparation de compositions pour le transfert d'acides nucleiques
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
HUE052571T2 (hu) * 2008-09-27 2021-05-28 Jina Pharmaceuticals Inc Lipid alapú gyógyszerészeti készítmények helyi alkalmazáshoz
EP3291797B1 (fr) 2015-05-04 2020-09-02 Versantis AG Procédé de préparation de vésicules à gradient ph transmembranaire
CN112545994B (zh) * 2020-11-19 2022-10-14 河南科技大学 一种小粒径、高稳定性多室及单室脂质体的同步制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310505A (en) * 1979-11-08 1982-01-12 California Institute Of Technology Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
EP0088046B1 (fr) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipides en phase aqueuse
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4663167A (en) * 1984-04-16 1987-05-05 The Board Of Regents Of The University Of Texas System Composition and method for treatment of disseminated fungal infections in mammals
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
JPS6176414A (ja) * 1984-09-21 1986-04-18 Shionogi & Co Ltd リポソーム製剤の製法

Also Published As

Publication number Publication date
EP0393145A1 (fr) 1990-10-24
JPH03501732A (ja) 1991-04-18
WO1989005636A1 (fr) 1989-06-29
EP0393145A4 (en) 1991-09-11

Similar Documents

Publication Publication Date Title
US4963297A (en) Spontaneous vesticulation of multilamellar liposomes
EP0555229B1 (fr) Accumulation d'acides amines et de peptides dans des liposomes
JP2574999B2 (ja) 脱水リポソーム医薬製剤
KR960013703B1 (ko) 완충능이 큰 완충액을 포함하는 리포좀 조성물
US5795589A (en) Liposomal antineoplastic agent compositions
US4857319A (en) Method for preserving liposomes
US5993850A (en) Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
US5077056A (en) Encapsulation of antineoplastic agents in liposomes
US5736155A (en) Encapsulation of antineoplastic agents in liposomes
US5616334A (en) Low toxicity drug-lipid systems
AU741784B2 (en) Modulation of drug loading in multivesicular liposomes
JPH08505882A (ja) リポソーム調製法及び物質のカプセル化方法
IE67152B1 (en) Low toxicity drug-lipid systems
CA1330199C (fr) Vesiculation spontanee de liposomes multilamellaires
Bally et al. Novel procedures for generating and loading liposomal systems
US20020016302A1 (en) Liposomal antitumor drug and its preparation
CA1329548C (fr) Preparation de liposomes et antibiotique
Ravivarapu et al. Formulation and characterization of azidothymidine-loaded liposomes

Legal Events

Date Code Title Description
MKLA Lapsed
MKLA Lapsed

Effective date: 20060614