SK17198A3 - Device in inhalers - Google Patents
Device in inhalers Download PDFInfo
- Publication number
- SK17198A3 SK17198A3 SK171-98A SK17198A SK17198A3 SK 17198 A3 SK17198 A3 SK 17198A3 SK 17198 A SK17198 A SK 17198A SK 17198 A3 SK17198 A3 SK 17198A3
- Authority
- SK
- Slovakia
- Prior art keywords
- gas
- air
- inhalation device
- constriction
- medicament
- Prior art date
Links
- 239000002245 particle Substances 0.000 claims abstract description 34
- 239000003814 drug Substances 0.000 claims abstract description 17
- 239000013543 active substance Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 description 18
- 230000014759 maintenance of location Effects 0.000 description 11
- 239000000126 substance Substances 0.000 description 8
- 239000006185 dispersion Substances 0.000 description 7
- 239000010419 fine particle Substances 0.000 description 7
- 230000001419 dependent effect Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000012254 powdered material Substances 0.000 description 5
- KFVSLSTULZVNPG-UHFFFAOYSA-N terbutaline sulfate Chemical compound [O-]S([O-])(=O)=O.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1.CC(C)(C)[NH2+]CC(O)C1=CC(O)=CC(O)=C1 KFVSLSTULZVNPG-UHFFFAOYSA-N 0.000 description 5
- 230000001133 acceleration Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 230000002776 aggregation Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 229940112141 dry powder inhaler Drugs 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 3
- 229960002848 formoterol Drugs 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 230000000717 retained effect Effects 0.000 description 3
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 2
- 238000005054 agglomeration Methods 0.000 description 2
- 229960004436 budesonide Drugs 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011164 primary particle Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 238000004220 aggregation Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000002664 inhalation therapy Methods 0.000 description 1
- 238000010102 injection blow moulding Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9502799A SE9502799D0 (sv) | 1995-08-10 | 1995-08-10 | Device in inhalers |
| PCT/SE1996/000969 WO1997005917A1 (en) | 1995-08-10 | 1996-07-23 | Device in inhalers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK17198A3 true SK17198A3 (en) | 1998-09-09 |
Family
ID=20399154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK171-98A SK17198A3 (en) | 1995-08-10 | 1996-07-23 | Device in inhalers |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5918594A (enExample) |
| EP (1) | EP0902700A1 (enExample) |
| JP (1) | JPH11510411A (enExample) |
| KR (1) | KR19990036287A (enExample) |
| CN (1) | CN1192702A (enExample) |
| AR (1) | AR003078A1 (enExample) |
| AU (1) | AU703128B2 (enExample) |
| BR (1) | BR9609880A (enExample) |
| CA (1) | CA2227547A1 (enExample) |
| CZ (1) | CZ38398A3 (enExample) |
| EE (1) | EE9800042A (enExample) |
| HU (1) | HUP9802454A3 (enExample) |
| ID (1) | ID15911A (enExample) |
| IL (1) | IL122760A0 (enExample) |
| IS (1) | IS4661A (enExample) |
| MX (1) | MX9800826A (enExample) |
| NO (1) | NO980565D0 (enExample) |
| NZ (1) | NZ313351A (enExample) |
| PL (1) | PL324865A1 (enExample) |
| SE (1) | SE9502799D0 (enExample) |
| SK (1) | SK17198A3 (enExample) |
| TR (1) | TR199800198T1 (enExample) |
| WO (1) | WO1997005917A1 (enExample) |
| ZA (1) | ZA966776B (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632456B1 (en) * | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| SE9700423D0 (sv) * | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhaler |
| DE69731563T2 (de) * | 1997-12-23 | 2005-10-20 | Euro-Celtique S.A. | Teilchenabscheider für einen inhalator |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| DK1142601T3 (da) * | 2000-04-07 | 2006-05-15 | Andi Ventis Ltd | Mundstykke til en partikelinhalator |
| WO2002013897A2 (en) | 2000-08-14 | 2002-02-21 | Advanced Inhalation Research, Inc. | Inhalation device and method |
| DK1337240T4 (en) | 2000-11-30 | 2015-01-05 | Vectura Ltd | A process for the preparation of particles for use in a pharmaceutical composition |
| US6626173B2 (en) | 2001-01-08 | 2003-09-30 | Iep Pharmaceutical Devices Inc. | Dry powder inhaler |
| US6443152B1 (en) * | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| US6722364B2 (en) * | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| US6644309B2 (en) * | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US6766799B2 (en) * | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| JP2005506855A (ja) * | 2001-05-10 | 2005-03-10 | ベクトゥラ デリバリー デバイシーズ リミテッド | 吸入器 |
| US6779520B2 (en) | 2001-10-30 | 2004-08-24 | Iep Pharmaceutical Devices Inc. | Breath actuated dry powder inhaler |
| AU2003220125B2 (en) | 2002-03-20 | 2006-06-15 | Mannkind Corporation | Inhalation apparatus |
| GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| EP2314298B1 (en) | 2004-08-23 | 2015-05-27 | MannKind Corporation | Microparticles comprising diketopiperazine salts for drug delivery |
| DK1901749T3 (en) | 2005-05-18 | 2016-10-24 | Raptor Pharmaceuticals Inc | Aerosolized fluoroquinolones AND USES THEREOF |
| US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
| DK1986679T3 (da) | 2006-02-22 | 2017-11-20 | Mannkind Corp | Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof |
| US7841338B2 (en) * | 2006-04-13 | 2010-11-30 | Boehringer Ingelheim International Gmbh | Dispensing device |
| EP2004258A1 (en) * | 2006-04-13 | 2008-12-24 | Boehringer Ingelheim Microparts Gmbh | Dispensing device |
| PT103481B (pt) * | 2006-05-16 | 2008-08-01 | Hovione Farmaciencia S A | Inalador de uso simples e método de inalação |
| WO2008091355A2 (en) * | 2007-01-24 | 2008-07-31 | Breathe Pharmaceuticals, Inc. | Drug transfer device |
| WO2008156586A2 (en) * | 2007-06-12 | 2008-12-24 | Alkermes, Inc. | Inhalation device for powdered substances |
| WO2009079078A1 (en) | 2007-12-14 | 2009-06-25 | Labogroup S.A.S. | Delivering aerosolizable food products |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CN103252007B (zh) | 2008-06-13 | 2016-06-22 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| JP5479465B2 (ja) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | 吸入努力をリアルタイムにプロファイルする対話式機器および方法 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| CA2739893C (en) | 2008-10-07 | 2016-10-04 | Mpex Pharmaceuticals, Inc. | Inhalation of levofloxacin for reducing lung inflammation |
| US8815838B2 (en) | 2008-10-07 | 2014-08-26 | David C. Griffith | Aerosol fluoroquinolone formulations for improved pharmacokinetics |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| EP3569235A1 (en) | 2009-09-04 | 2019-11-20 | Horizon Orphan LLC | Use of aerosolized levofloxacin for treating cystic fibrosis |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
| CN101856531A (zh) * | 2010-06-22 | 2010-10-13 | 于清 | 用于药物输送的高效干粉吸入器及其药物输送方法 |
| JP6021117B2 (ja) | 2011-01-31 | 2016-11-02 | ジェノア ファーマシューティカルズ，インク． | エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用 |
| CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| WO2013036881A2 (en) * | 2011-09-07 | 2013-03-14 | Syphase, Llc | Dry powder inhalation device |
| WO2013063160A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
| SG11201500218VA (en) | 2012-07-12 | 2015-03-30 | Mannkind Corp | Dry powder drug delivery systems and methods |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
| CN105451716A (zh) | 2013-07-18 | 2016-03-30 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
| US20150044288A1 (en) | 2013-07-31 | 2015-02-12 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
| WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
| EP4491180A1 (en) | 2014-01-10 | 2025-01-15 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| DE102014017409B4 (de) * | 2014-11-26 | 2016-06-09 | Klaus Dieter Beller | Einzeldosis-Pulverinhalator und Verfahren zu dessen Herstellung |
| CA3057683A1 (en) | 2017-03-28 | 2018-10-04 | Concentrx Pharmaceuticals, Inc. | Devices and methods for delivering dry powder medicaments |
| WO2022240897A1 (en) | 2021-05-10 | 2022-11-17 | Sepelo Therapeutics, Llc | Pharmaceutical composition comprising delafloxacin for administration into the lung |
| WO2023028364A1 (en) | 2021-08-27 | 2023-03-02 | Sepelo Therapeutics, Llc | Targeted compositions and uses therof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2214032A (en) * | 1939-06-23 | 1940-09-10 | Walter B Stewart | Apparatus for administering powdered aluminum |
| US2829642A (en) * | 1954-10-18 | 1958-04-08 | Melfy Frank A De | Nebulizer having means for eliminating failures |
| US2992645A (en) * | 1958-05-06 | 1961-07-18 | Benger Lab Ltd | Disperser for powders |
| US3795244A (en) * | 1973-02-02 | 1974-03-05 | Syntex Corp | Inhalation device |
| YU41046B (en) * | 1974-08-22 | 1986-10-31 | Schering Ag | Medicine inholating device |
| SE453566B (sv) * | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
| US4739754A (en) * | 1986-05-06 | 1988-04-26 | Shaner William T | Suction resistant inhalator |
| US5507281A (en) * | 1990-08-30 | 1996-04-16 | Boehringer Ingelheim Kg | Device for initiating a mechanical switching operation in synchronism with the breathing |
| SE9002895D0 (sv) * | 1990-09-12 | 1990-09-12 | Astra Ab | Inhalation devices for dispensing powders i |
| GB9027234D0 (en) * | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| EP0558879B1 (en) * | 1992-03-04 | 1997-05-14 | Astra Aktiebolag | Disposable inhaler |
| US5483954A (en) * | 1994-06-10 | 1996-01-16 | Mecikalski; Mark B. | Inhaler and medicated package |
-
1995
- 1995-08-10 SE SE9502799A patent/SE9502799D0/xx unknown
-
1996
- 1996-07-11 ID IDP961983A patent/ID15911A/id unknown
- 1996-07-23 CA CA002227547A patent/CA2227547A1/en not_active Abandoned
- 1996-07-23 TR TR1998/00198T patent/TR199800198T1/xx unknown
- 1996-07-23 BR BR9609880A patent/BR9609880A/pt not_active IP Right Cessation
- 1996-07-23 KR KR1019980700955A patent/KR19990036287A/ko not_active Withdrawn
- 1996-07-23 CZ CZ98383A patent/CZ38398A3/cs unknown
- 1996-07-23 NZ NZ313351A patent/NZ313351A/en unknown
- 1996-07-23 WO PCT/SE1996/000969 patent/WO1997005917A1/en not_active Ceased
- 1996-07-23 AU AU65391/96A patent/AU703128B2/en not_active Ceased
- 1996-07-23 CN CN96196170A patent/CN1192702A/zh active Pending
- 1996-07-23 MX MX9800826A patent/MX9800826A/es unknown
- 1996-07-23 EE EE9800042A patent/EE9800042A/xx unknown
- 1996-07-23 IL IL12276096A patent/IL122760A0/xx unknown
- 1996-07-23 PL PL96324865A patent/PL324865A1/xx unknown
- 1996-07-23 EP EP96925235A patent/EP0902700A1/en not_active Withdrawn
- 1996-07-23 HU HU9802454A patent/HUP9802454A3/hu unknown
- 1996-07-23 US US08/817,800 patent/US5918594A/en not_active Expired - Fee Related
- 1996-07-23 JP JP9508364A patent/JPH11510411A/ja not_active Ceased
- 1996-07-23 SK SK171-98A patent/SK17198A3/sk unknown
- 1996-07-29 AR AR10379896A patent/AR003078A1/es unknown
- 1996-08-08 ZA ZA9606776A patent/ZA966776B/xx unknown
-
1998
- 1998-01-27 IS IS4661A patent/IS4661A/is unknown
- 1998-02-10 NO NO980565A patent/NO980565D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ313351A (en) | 1999-04-29 |
| IL122760A0 (en) | 1998-08-16 |
| ZA966776B (en) | 1997-02-10 |
| KR19990036287A (ko) | 1999-05-25 |
| WO1997005917A1 (en) | 1997-02-20 |
| PL324865A1 (en) | 1998-06-22 |
| IS4661A (is) | 1998-01-27 |
| CZ38398A3 (cs) | 1998-05-13 |
| SE9502799D0 (sv) | 1995-08-10 |
| NO980565L (no) | 1998-02-10 |
| US5918594A (en) | 1999-07-06 |
| AU703128B2 (en) | 1999-03-18 |
| CN1192702A (zh) | 1998-09-09 |
| EE9800042A (et) | 1998-08-17 |
| NO980565D0 (no) | 1998-02-10 |
| AR003078A1 (es) | 1998-05-27 |
| MX9800826A (es) | 1998-04-30 |
| ID15911A (id) | 1997-08-21 |
| AU6539196A (en) | 1997-03-05 |
| CA2227547A1 (en) | 1997-02-20 |
| HUP9802454A3 (en) | 1999-04-28 |
| EP0902700A1 (en) | 1999-03-24 |
| BR9609880A (pt) | 1999-03-23 |
| TR199800198T1 (xx) | 1998-06-22 |
| HUP9802454A2 (hu) | 1999-02-01 |
| JPH11510411A (ja) | 1999-09-14 |
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