SK16994A3 - Cyclic urethanes used as antiarrhythmic and antifibrillatory agents and pharmaceutical compounds containing these agents - Google Patents

Cyclic urethanes used as antiarrhythmic and antifibrillatory agents and pharmaceutical compounds containing these agents Download PDF

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Publication number
SK16994A3
SK16994A3 SK169-94A SK16994A SK16994A3 SK 16994 A3 SK16994 A3 SK 16994A3 SK 16994 A SK16994 A SK 16994A SK 16994 A3 SK16994 A3 SK 16994A3
Authority
SK
Slovakia
Prior art keywords
group
heterocycle
alkyl
methyl
substituted
Prior art date
Application number
SK169-94A
Other languages
English (en)
Slovak (sk)
Inventor
Stanford S Pelosi Jr
Chia-Nien Yu
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of SK16994A3 publication Critical patent/SK16994A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
SK169-94A 1991-08-14 1992-08-10 Cyclic urethanes used as antiarrhythmic and antifibrillatory agents and pharmaceutical compounds containing these agents SK16994A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74486591A 1991-08-14 1991-08-14
PCT/US1992/006682 WO1993004064A1 (en) 1991-08-14 1992-08-10 Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents

Publications (1)

Publication Number Publication Date
SK16994A3 true SK16994A3 (en) 1995-03-08

Family

ID=24994270

Family Applications (1)

Application Number Title Priority Date Filing Date
SK169-94A SK16994A3 (en) 1991-08-14 1992-08-10 Cyclic urethanes used as antiarrhythmic and antifibrillatory agents and pharmaceutical compounds containing these agents

Country Status (23)

Country Link
US (1) US5994354A (sv)
EP (2) EP0599968B1 (sv)
JP (1) JPH06510285A (sv)
AT (1) ATE188696T1 (sv)
AU (1) AU665367B2 (sv)
BR (1) BR9206353A (sv)
CA (1) CA2115029C (sv)
CZ (1) CZ283323B6 (sv)
DE (1) DE69230563T2 (sv)
DK (1) DK0599968T3 (sv)
ES (1) ES2141725T3 (sv)
FI (1) FI940658A0 (sv)
GR (1) GR3032432T3 (sv)
HU (1) HUT70144A (sv)
IL (1) IL102791A (sv)
MX (1) MX9204736A (sv)
NO (1) NO300807B1 (sv)
NZ (1) NZ243936A (sv)
PL (1) PL171280B1 (sv)
PT (1) PT100775B (sv)
RU (1) RU2125568C1 (sv)
SK (1) SK16994A3 (sv)
WO (1) WO1993004064A1 (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3040473B2 (ja) * 1991-08-14 2000-05-15 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な新規４−オキソ環式尿素類
DE69228751T2 (de) * 1991-08-14 1999-10-07 Procter & Gamble Pharmaceuticals, Norwich Zyklische harnstoffe mit antiarrhythmischer und antifibrillatorischer wirkung
BR9206353A (pt) * 1991-08-14 1995-11-07 Procter & Gamble Pharma Uretanos cíclicos utilizáveis como agentes antiarrítmicos e antifibrilatórios
NZ506773A (en) 1998-04-29 2004-03-26 Procter & Gamble Process for making 1, 3-disubstituted-4-oxocyclic ureas
BR9910074A (pt) 1998-04-29 2000-12-26 Procter & Gamble Processo para fabricação de uréias 1,3-di-substituìdas-4-oxocìclicas
RU2488591C2 (ru) * 2007-09-26 2013-07-27 Маунт Синай Скул Оф Медсин Аналоги азацитидина и их применение

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NL285000A (sv) *
US2802002A (en) * 1956-07-18 1957-08-06 Norwich Pharma Co Series of new nu-(5-nitro-2-furyl) alkylidene-3-amino-5-tertiaryamino-methyl-2-oxazolidones and the preparation thereof
GB843834A (en) * 1957-05-13 1960-08-10 Norwich Pharma Co N-(5-nitro-2-furyl)-alkylidene-3-amino-5-tertiaryaminomethyl-2-oxazolidones and chemotherapeutic compositions containing them
FR1274399A (fr) * 1958-01-23 1961-10-27 Norwich Pharma Co Procédé perfectionné de préparation de dérivés du 5-nitro-2-formyl-furan
NL104211C (sv) * 1958-02-28
US3004888A (en) * 1959-01-12 1961-10-17 Pfizer & Co C Mastitis treatment
NL266216A (sv) * 1960-07-12
FR385M (fr) * 1960-08-17 1961-03-24 Norwich Pharma Co Nouveau médicament pour le traitement des infections staphylococciques et analogues.
CH398599A (fr) * 1961-03-24 1966-03-15 Om Lab Sa Procédé de préparation d'hydrazones de l'a-bromo-B-(5-nitro-2-furyl)acroléine
BE633841A (sv) * 1962-06-21
BE635608A (sv) * 1962-08-01
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
US3318878A (en) * 1966-04-14 1967-05-09 Smith Kline French Lab Nitrothiophene compounds
GB1279408A (en) * 1968-09-12 1972-06-28 Ciba Geigy Ag 5-nitro-2-furfurylideneamino-oxazolidinones
US3839567A (en) * 1969-04-17 1974-10-01 Schering Ag Pharmaceutical compositions comprising 3-(5-nitro-2-imidazolyl-methylen-amino)-2-oxazolidinones and their use in trichomoniasia
US3906101A (en) * 1969-06-05 1975-09-16 Ciba Geigy Corp Pharmaceutical compositions containing substituted 5-nitrofurfurylideneamino-oxazolidinones
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4393204A (en) * 1982-05-21 1983-07-12 Norwich Eaton Pharmaceuticals, Inc. 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US4720580A (en) * 1984-09-21 1988-01-19 American Home Products Corporation N-(aminoalkylene)benzenesulfonamides
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4713832A (en) * 1986-04-11 1987-12-15 Ampex Corporation Programmable divider up/down counter with anti-aliasing feature and asynchronous read/write
IL79174A0 (en) * 1986-06-05 1986-09-30 Abic Ltd Water soluble salt of furaltadone
US4895867A (en) * 1986-06-26 1990-01-23 Norwich Eaton Pharmaceuticals, Inc. 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents
US4886794A (en) * 1987-05-07 1989-12-12 A. H. Robins Company, Incorporated 4-[(α,α-diaryl)-hydroxymethyl]-1-piperidinylalkyl-cyclic carbamate derivatives as allergic response inhibitors
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US4870095A (en) * 1988-06-13 1989-09-26 Sterling Drug, Inc. 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
EP0347733A1 (en) * 1988-06-20 1989-12-27 Eisai Co., Ltd. Optically active hydantoin derivatives
DE68929303T2 (de) * 1988-09-15 2002-05-02 Pharmacia & Upjohn Co., Kalamazoo 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
US5091426A (en) * 1989-06-23 1992-02-25 Norwich Eaton Pharmaceuticals, Inc. 5-phenyl-2-furan ketones and use as antiepileptic agents
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US5066662A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors
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BR9206353A (pt) * 1991-08-14 1995-11-07 Procter & Gamble Pharma Uretanos cíclicos utilizáveis como agentes antiarrítmicos e antifibrilatórios

Also Published As

Publication number Publication date
DE69230563T2 (de) 2000-09-14
BR9206353A (pt) 1995-11-07
MX9204736A (es) 1993-11-01
FI940658A (sv) 1994-02-11
PT100775A (pt) 1994-01-31
ATE188696T1 (de) 2000-01-15
EP0599968B1 (en) 2000-01-12
CZ283323B6 (cs) 1998-02-18
NO940496D0 (no) 1994-02-14
NZ243936A (en) 1996-10-28
AU2467892A (en) 1993-03-16
AU665367B2 (en) 1996-01-04
HUT70144A (en) 1995-09-28
DE69230563D1 (de) 2000-02-17
IL102791A0 (en) 1993-01-31
PT100775B (pt) 1999-09-30
ES2141725T3 (es) 2000-04-01
EP0599968A1 (en) 1994-06-08
EP0957103A1 (en) 1999-11-17
GR3032432T3 (en) 2000-05-31
JPH06510285A (ja) 1994-11-17
DK0599968T3 (da) 2000-04-17
RU2125568C1 (ru) 1999-01-27
HU9400403D0 (en) 1994-05-30
FI940658A0 (sv) 1994-02-11
CA2115029C (en) 2002-03-26
CZ27894A3 (en) 1995-07-12
PL171280B1 (pl) 1997-03-28
NO940496L (no) 1994-02-14
US5994354A (en) 1999-11-30
IL102791A (en) 1998-06-15
WO1993004064A1 (en) 1993-03-04
CA2115029A1 (en) 1993-03-04
NO300807B1 (no) 1997-07-28

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