FI940658A - Cykliska uretaner, vilka är användbara som antiarrytmiska och hjärtflimmer motarbetande ämnen - Google Patents

Cykliska uretaner, vilka är användbara som antiarrytmiska och hjärtflimmer motarbetande ämnen Download PDF

Info

Publication number
FI940658A
FI940658A FI940658A FI940658A FI940658A FI 940658 A FI940658 A FI 940658A FI 940658 A FI940658 A FI 940658A FI 940658 A FI940658 A FI 940658A FI 940658 A FI940658 A FI 940658A
Authority
FI
Finland
Prior art keywords
antiarrhythmics
useful
unsaturated
cyclic urethanes
urethanes useful
Prior art date
Application number
FI940658A
Other languages
English (en)
Finnish (fi)
Other versions
FI940658A0 (sv
Inventor
Jr Stanford Salvatore Pelosi
Chia-Nien Yu
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of FI940658A0 publication Critical patent/FI940658A0/sv
Publication of FI940658A publication Critical patent/FI940658A/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
FI940658A 1991-08-14 1994-02-11 Cykliska uretaner, vilka är användbara som antiarrytmiska och hjärtflimmer motarbetande ämnen FI940658A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74486591A 1991-08-14 1991-08-14
PCT/US1992/006682 WO1993004064A1 (en) 1991-08-14 1992-08-10 Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents

Publications (2)

Publication Number Publication Date
FI940658A0 FI940658A0 (sv) 1994-02-11
FI940658A true FI940658A (sv) 1994-02-11

Family

ID=24994270

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940658A FI940658A (sv) 1991-08-14 1994-02-11 Cykliska uretaner, vilka är användbara som antiarrytmiska och hjärtflimmer motarbetande ämnen

Country Status (23)

Country Link
US (1) US5994354A (sv)
EP (2) EP0599968B1 (sv)
JP (1) JPH06510285A (sv)
AT (1) ATE188696T1 (sv)
AU (1) AU665367B2 (sv)
BR (1) BR9206353A (sv)
CA (1) CA2115029C (sv)
CZ (1) CZ283323B6 (sv)
DE (1) DE69230563T2 (sv)
DK (1) DK0599968T3 (sv)
ES (1) ES2141725T3 (sv)
FI (1) FI940658A (sv)
GR (1) GR3032432T3 (sv)
HU (1) HUT70144A (sv)
IL (1) IL102791A (sv)
MX (1) MX9204736A (sv)
NO (1) NO300807B1 (sv)
NZ (1) NZ243936A (sv)
PL (1) PL171280B1 (sv)
PT (1) PT100775B (sv)
RU (1) RU2125568C1 (sv)
SK (1) SK16994A3 (sv)
WO (1) WO1993004064A1 (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU665209B2 (en) * 1991-08-14 1995-12-21 Procter & Gamble Pharmaceuticals Novel cyclic ureas useful as antiarrhythmic and antifibrillatory agents
HU221317B1 (en) * 1991-08-14 2002-09-28 Procter & Gamble Pharma 2,4-imidazolidinedione derivatives and antiarrhythmic and antifibrillatory compositions containing them, and process for producing them
HUT70144A (en) * 1991-08-14 1995-09-28 Procter & Gamble Pharma Cyclic urethaanes useful as antiarrhythmic and antifibrillatory agents, pharmaceutical compositions containing them, and process for their preparation
TR200003137T2 (tr) 1998-04-29 2001-02-21 The Procter & Gamble Company 1,3-İki defa yer değiştirmiş-4-oksosiklik üreler
CN1298402A (zh) 1998-04-29 2001-06-06 宝洁公司 1,3-二取代-4-氧代环状脲的制备方法
NZ583824A (en) * 2007-09-26 2012-06-29 Sinai School Medicine Azacytidine analogues and uses thereof

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624402A (sv) *
US2802002A (en) * 1956-07-18 1957-08-06 Norwich Pharma Co Series of new nu-(5-nitro-2-furyl) alkylidene-3-amino-5-tertiaryamino-methyl-2-oxazolidones and the preparation thereof
GB843834A (en) * 1957-05-13 1960-08-10 Norwich Pharma Co N-(5-nitro-2-furyl)-alkylidene-3-amino-5-tertiaryaminomethyl-2-oxazolidones and chemotherapeutic compositions containing them
FR1274399A (fr) * 1958-01-23 1961-10-27 Norwich Pharma Co Procédé perfectionné de préparation de dérivés du 5-nitro-2-formyl-furan
NL104211C (sv) * 1958-02-28
US3004888A (en) * 1959-01-12 1961-10-17 Pfizer & Co C Mastitis treatment
NL266216A (sv) * 1960-07-12
FR385M (fr) * 1960-08-17 1961-03-24 Norwich Pharma Co Nouveau médicament pour le traitement des infections staphylococciques et analogues.
CH398599A (fr) * 1961-03-24 1966-03-15 Om Lab Sa Procédé de préparation d'hydrazones de l'a-bromo-B-(5-nitro-2-furyl)acroléine
BE633841A (sv) * 1962-06-21
NL120945C (sv) * 1962-08-01
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
US3318878A (en) * 1966-04-14 1967-05-09 Smith Kline French Lab Nitrothiophene compounds
GB1279408A (en) * 1968-09-12 1972-06-28 Ciba Geigy Ag 5-nitro-2-furfurylideneamino-oxazolidinones
US3839567A (en) * 1969-04-17 1974-10-01 Schering Ag Pharmaceutical compositions comprising 3-(5-nitro-2-imidazolyl-methylen-amino)-2-oxazolidinones and their use in trichomoniasia
US3906101A (en) * 1969-06-05 1975-09-16 Ciba Geigy Corp Pharmaceutical compositions containing substituted 5-nitrofurfurylideneamino-oxazolidinones
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4393204A (en) * 1982-05-21 1983-07-12 Norwich Eaton Pharmaceuticals, Inc. 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US4720580A (en) * 1984-09-21 1988-01-19 American Home Products Corporation N-(aminoalkylene)benzenesulfonamides
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4713832A (en) * 1986-04-11 1987-12-15 Ampex Corporation Programmable divider up/down counter with anti-aliasing feature and asynchronous read/write
IL79174A0 (en) * 1986-06-05 1986-09-30 Abic Ltd Water soluble salt of furaltadone
US4895867A (en) * 1986-06-26 1990-01-23 Norwich Eaton Pharmaceuticals, Inc. 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents
US4886794A (en) * 1987-05-07 1989-12-12 A. H. Robins Company, Incorporated 4-[(α,α-diaryl)-hydroxymethyl]-1-piperidinylalkyl-cyclic carbamate derivatives as allergic response inhibitors
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US4870095A (en) * 1988-06-13 1989-09-26 Sterling Drug, Inc. 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
JPH0276882A (ja) * 1988-06-20 1990-03-16 Eisai Co Ltd 光学活性ヒダントイン誘導体
DE68918792T2 (de) * 1988-09-15 1995-03-30 Upjohn Co 5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one.
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
US5091426A (en) * 1989-06-23 1992-02-25 Norwich Eaton Pharmaceuticals, Inc. 5-phenyl-2-furan ketones and use as antiepileptic agents
US4966967A (en) * 1989-09-15 1990-10-30 Berlex Laboratories, Inc. 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US4963561A (en) * 1990-02-28 1990-10-16 Sterling Drug Inc. Imidazopyridines, their preparation and use
US5066662A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors
US5086055A (en) * 1990-12-24 1992-02-04 A. H. Robins Company, Incorporated Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives useful in the treatment of allergic conditions
HUT70144A (en) * 1991-08-14 1995-09-28 Procter & Gamble Pharma Cyclic urethaanes useful as antiarrhythmic and antifibrillatory agents, pharmaceutical compositions containing them, and process for their preparation

Also Published As

Publication number Publication date
MX9204736A (es) 1993-11-01
IL102791A (en) 1998-06-15
GR3032432T3 (en) 2000-05-31
NO940496D0 (no) 1994-02-14
AU665367B2 (en) 1996-01-04
FI940658A0 (sv) 1994-02-11
ES2141725T3 (es) 2000-04-01
EP0599968B1 (en) 2000-01-12
JPH06510285A (ja) 1994-11-17
NO300807B1 (no) 1997-07-28
PT100775A (pt) 1994-01-31
EP0599968A1 (en) 1994-06-08
DE69230563D1 (de) 2000-02-17
SK16994A3 (en) 1995-03-08
DK0599968T3 (da) 2000-04-17
HUT70144A (en) 1995-09-28
WO1993004064A1 (en) 1993-03-04
ATE188696T1 (de) 2000-01-15
CZ283323B6 (cs) 1998-02-18
AU2467892A (en) 1993-03-16
DE69230563T2 (de) 2000-09-14
CZ27894A3 (en) 1995-07-12
BR9206353A (pt) 1995-11-07
US5994354A (en) 1999-11-30
HU9400403D0 (en) 1994-05-30
NZ243936A (en) 1996-10-28
NO940496L (no) 1994-02-14
PL171280B1 (pl) 1997-03-28
RU2125568C1 (ru) 1999-01-27
CA2115029C (en) 2002-03-26
CA2115029A1 (en) 1993-03-04
IL102791A0 (en) 1993-01-31
EP0957103A1 (en) 1999-11-17
PT100775B (pt) 1999-09-30

Similar Documents

Publication Publication Date Title
BR1100621A (pt) Compostos
DK598589D0 (da) Thiazolforbindelse og fungicid indeholdende en saadan forbindelse
SE8004783L (sv) Delta?722-1,2,4triazolin-5-on-derivat
DE69010375D1 (de) Protease-Hemmer.
ES456287A1 (es) Procedimiento para la preparacion de derivados de ladano po-lioxigenados.
NO920767D0 (no) Pyranylcyanoguanidin-derivater
NZ507106A (en) Preparation of cyclohexene carboxylate derivatives
ES2077070T3 (es) Intermedio de sintesis de 2-alquiniladenosina, produccion de dicho intermedio, produccion de 2-alquiniladenosina a partir de dicho intermedio, y derivado de 2-alquiniladenosina estable.
FI940658A (sv) Cykliska uretaner, vilka är användbara som antiarrytmiska och hjärtflimmer motarbetande ämnen
DK129189A (da) Benzophenonderivater
WO1991000729A3 (en) Bis-dioxopiperazines, and their use as protecting agents
JPS5358506A (en) Detergent composition
DE69830653D1 (en) Chelatisierungsmitteln
ATE62131T1 (de) Pharmazeutische zusammenstellung fuer die prophylaxe oder behandlung von tierhaltungsketose.
EP0626369A4 (en) BENZENE SULPHONAMIDE DERIVATIVES.
IT1223067B (it) Composto fotocromatico ed articoli fotocromatici che lo contengono
ES8705426A1 (es) Un procedimiento para la preparacion de un derivado de piperazina.
ES463826A1 (es) Procedimiento para la preparacion de esteres de acidos o- (2,3-epoxipropil)-hidroximicos
TH14336EX (th) อนุพันธ์ต่าง ๆ ของพิเพอริดีน
DK480389D0 (da) Antitumorstof, fremgangsmaade til dets fremstilling og anticancermiddel indeholdende stoffet
KR920702364A (ko) 신규 세팔로스포린계 화합물
DK305890A (da) Aminoketaler, deres fremstilling og deres anvendelse som fungicider
TH17400EX (th) สารผสม
TH35753EX (th) โพลิออลชนิดใหม่
TH35753A (th) โพลิออลชนิดใหม่