SK169897A3 - Pharmaceutical composition with anaesthetic effect - Google Patents

Pharmaceutical composition with anaesthetic effect Download PDF

Info

Publication number
SK169897A3
SK169897A3 SK1698-97A SK169897A SK169897A3 SK 169897 A3 SK169897 A3 SK 169897A3 SK 169897 A SK169897 A SK 169897A SK 169897 A3 SK169897 A3 SK 169897A3
Authority
SK
Slovakia
Prior art keywords
pharmaceutical composition
surfactant
weight
composition according
local anesthetic
Prior art date
Application number
SK1698-97A
Other languages
English (en)
Slovak (sk)
Inventor
Arne Brodin
Raymond Fynes
Lars Heijl
Adela Nyqvist-Mayer
Marie Scherlund
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SK169897A3 publication Critical patent/SK169897A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK1698-97A 1996-04-12 1997-04-01 Pharmaceutical composition with anaesthetic effect SK169897A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9601421A SE9601421D0 (sv) 1996-04-12 1996-04-12 New composition
PCT/SE1997/000566 WO1997038675A1 (en) 1996-04-12 1997-04-01 New pharmaceutical composition with anaesthetic effect

Publications (1)

Publication Number Publication Date
SK169897A3 true SK169897A3 (en) 1998-07-08

Family

ID=20402194

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1698-97A SK169897A3 (en) 1996-04-12 1997-04-01 Pharmaceutical composition with anaesthetic effect

Country Status (30)

Country Link
US (1) US6031007A (zh)
EP (1) EP0833612B1 (zh)
JP (2) JPH11501678A (zh)
KR (1) KR100508601B1 (zh)
CN (1) CN1149072C (zh)
AR (1) AR006484A1 (zh)
AT (1) ATE248584T1 (zh)
AU (1) AU716540B2 (zh)
BR (1) BR9702147A (zh)
CA (1) CA2222676C (zh)
CZ (1) CZ371197A3 (zh)
DE (1) DE69724545T2 (zh)
DK (1) DK0833612T3 (zh)
EE (1) EE9700363A (zh)
ES (1) ES2203799T3 (zh)
HK (1) HK1010144A1 (zh)
HU (1) HUP9903544A3 (zh)
ID (1) ID16420A (zh)
IL (1) IL122447A (zh)
IS (1) IS4618A (zh)
NO (1) NO318239B1 (zh)
NZ (1) NZ329246A (zh)
PL (1) PL324170A1 (zh)
RU (1) RU2185153C2 (zh)
SE (1) SE9601421D0 (zh)
SK (1) SK169897A3 (zh)
TR (1) TR199701584T1 (zh)
TW (1) TW473386B (zh)
WO (1) WO1997038675A1 (zh)
ZA (1) ZA973022B (zh)

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FR2764800B1 (fr) * 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
DE69912441T2 (de) * 1998-08-19 2004-08-19 Skyepharma Canada Inc., Verdun Injizierbare wässerige propofoldispersionen
US6528086B2 (en) * 1999-09-28 2003-03-04 Zars, Inc. Methods and apparatus for drug delivery involving phase changing formulations
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
KR100416646B1 (ko) * 2000-08-14 2004-02-05 구주제약주식회사 리도카인을 함유한 조루치료용 마이크로에멀젼 하이드로겔 제형의 약학 조성물
GB0120701D0 (en) 2001-08-24 2001-10-17 Maelor Pharmaceuticals Ltd Pharmaceutical formulations
US20040087520A1 (en) * 2002-10-25 2004-05-06 Chowdhury Dipak K. Compositions and methods for delivery of therapeutic agents
TW200410717A (en) * 2002-12-31 2004-07-01 Ind Tech Res Inst Delivery system for control release of temperature sensitive bioactive material
AU2003900887A0 (en) * 2003-02-27 2003-03-13 Novasel Australia Pty Ltd Poloxamer emulsion preparations
US8802116B2 (en) 2003-02-27 2014-08-12 Novasel Australia Pty. Ltd. Poloxamer emulsion preparations
BR0301968A (pt) * 2003-05-22 2005-06-28 Cristalia Prod Quimicos Farm Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica
JP4669960B2 (ja) * 2003-06-03 2011-04-13 株式会社 メドレックス 局所麻酔薬を含有する口中用または咽頭部用製剤
US7943179B2 (en) * 2003-09-23 2011-05-17 Massachusetts Institute Of Technology pH triggerable polymeric particles
US20050123596A1 (en) * 2003-09-23 2005-06-09 Kohane Daniel S. pH-triggered microparticles
US20070232695A1 (en) * 2004-01-28 2007-10-04 Collegium Pharmaceutical, Inc. Gelled Periodontal Anesthetic Preparation
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US8741332B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US8907153B2 (en) 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
WO2006037047A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The r-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
CA2655809C (en) * 2006-07-21 2013-10-01 Bridge Pharma, Inc. Dermal anesthetic compounds
US20080021068A1 (en) * 2006-07-24 2008-01-24 Akorn, Inc. Aqueous gel formulation and method for inducing topical anesthesia
US20090123527A1 (en) * 2006-07-24 2009-05-14 Akorn, Inc. Method of inducing topical anesthesia and transdermal patch
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9012477B2 (en) 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
EP2421496A4 (en) * 2009-04-22 2014-01-15 Agency Science Tech & Res EMULSIONS FOR TRANSDERMAL ADMINISTRATION
WO2011074015A2 (en) 2009-12-17 2011-06-23 Themis Medicare Limited Novel composition of pharmaceutical product to treat sexual dysfunction
MX2012008168A (es) 2010-01-14 2013-02-07 Nuvo Res Inc Formulaciones anestesicas locales que forman solidos para control del dolor.
BR112012024885A2 (pt) 2010-04-01 2016-06-21 Pharmanest Ab composições bioadesivas de anestésicos locais
WO2011121074A1 (en) * 2010-04-01 2011-10-06 Pharmanest Ab Thermogelling anaesthetic compositions
US20140066481A1 (en) 2010-04-01 2014-03-06 Pharmanest Ab Water-Free Pharmaceutical Compositions Suitable for Local Anaesthetics
WO2011133177A1 (en) * 2010-04-21 2011-10-27 Teikoku Pharma Usa, Inc. Local anesthetic emulsion compositions and methods of making and using the same
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
US20140275170A1 (en) * 2013-03-14 2014-09-18 Jsn I, Llc Taste masking of anesthetics and analgesics
WO2017039559A1 (en) 2015-09-02 2017-03-09 T.C. Istanbul Medipol Universitesi Formulations of benzocaine loaded microemulsion based hydrogels for therapeutic purposes and their production method
WO2020182535A1 (en) 2019-03-08 2020-09-17 Bayer Oy Uterine sound tube with anaesthetic applicator
CN113244167B (zh) * 2021-05-20 2022-11-29 河北科技大学 一种盐酸利多卡因凝胶及其制备方法

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Also Published As

Publication number Publication date
NZ329246A (en) 2000-06-23
SE9601421D0 (sv) 1996-04-12
MX9709941A (es) 1998-03-29
CZ371197A3 (cs) 1998-06-17
ES2203799T3 (es) 2004-04-16
EE9700363A (et) 1998-06-15
EP0833612B1 (en) 2003-09-03
HUP9903544A3 (en) 2000-07-28
AU2416897A (en) 1997-11-07
ZA973022B (en) 1997-10-13
ATE248584T1 (de) 2003-09-15
CA2222676A1 (en) 1997-10-23
CN1188407A (zh) 1998-07-22
NO318239B1 (no) 2005-02-21
NO975831L (no) 1997-12-11
EP0833612A1 (en) 1998-04-08
WO1997038675A1 (en) 1997-10-23
KR100508601B1 (ko) 2006-03-23
AR006484A1 (es) 1999-08-25
IL122447A (en) 2001-04-30
TR199701584T1 (xx) 1999-03-22
DE69724545T2 (de) 2004-06-03
HK1010144A1 (en) 1999-06-17
NO975831D0 (no) 1997-12-11
JP2004149544A (ja) 2004-05-27
HUP9903544A2 (hu) 2000-06-28
PL324170A1 (en) 1998-05-11
CN1149072C (zh) 2004-05-12
CA2222676C (en) 2008-01-22
RU2185153C2 (ru) 2002-07-20
BR9702147A (pt) 1999-07-20
IL122447A0 (en) 1998-06-15
DK0833612T3 (da) 2003-12-01
IS4618A (is) 1997-11-21
JPH11501678A (ja) 1999-02-09
ID16420A (id) 1997-09-25
KR19990022833A (ko) 1999-03-25
US6031007A (en) 2000-02-29
AU716540B2 (en) 2000-02-24
TW473386B (en) 2002-01-21
DE69724545D1 (de) 2003-10-09

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