SI9200104A - Imidazo(2,1-a)(pyrrolo, thieno or furano)(3,2-d)azepin derivatives, compositions and methods of use - Google Patents

Imidazo(2,1-a)(pyrrolo, thieno or furano)(3,2-d)azepin derivatives, compositions and methods of use Download PDF

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Publication number
SI9200104A
SI9200104A SI19929200104A SI9200104A SI9200104A SI 9200104 A SI9200104 A SI 9200104A SI 19929200104 A SI19929200104 A SI 19929200104A SI 9200104 A SI9200104 A SI 9200104A SI 9200104 A SI9200104 A SI 9200104A
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SI
Slovenia
Prior art keywords
formula
alkyl
compound
het
substituted
Prior art date
Application number
SI19929200104A
Other languages
English (en)
Slovenian (sl)
Inventor
Frans Eduard Janssen
Gaston Stanislas Marcella Diels
Joseph Elisabeth Leenaerts
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of SI9200104A publication Critical patent/SI9200104A/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Paper (AREA)
  • Detergent Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Lubricants (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SI19929200104A 1991-06-13 1992-06-12 Imidazo(2,1-a)(pyrrolo, thieno or furano)(3,2-d)azepin derivatives, compositions and methods of use SI9200104A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71448791A 1991-06-13 1991-06-13

Publications (1)

Publication Number Publication Date
SI9200104A true SI9200104A (en) 1992-12-31

Family

ID=24870247

Family Applications (1)

Application Number Title Priority Date Filing Date
SI19929200104A SI9200104A (en) 1991-06-13 1992-06-12 Imidazo(2,1-a)(pyrrolo, thieno or furano)(3,2-d)azepin derivatives, compositions and methods of use

Country Status (26)

Country Link
US (1) US5461050A (sh)
EP (2) EP0518434A1 (sh)
JP (1) JP3182421B2 (sh)
KR (1) KR100247504B1 (sh)
CN (1) CN1033587C (sh)
AT (1) ATE247118T1 (sh)
AU (1) AU652841B2 (sh)
CA (1) CA2102889C (sh)
DE (1) DE69233161T2 (sh)
ES (1) ES2204892T3 (sh)
FI (1) FI104077B (sh)
HR (1) HRP920156A2 (sh)
HU (1) HU221013B1 (sh)
IE (1) IE921919A1 (sh)
IL (1) IL101851A (sh)
MA (1) MA22554A1 (sh)
MX (1) MX9202860A (sh)
NO (2) NO300689B1 (sh)
NZ (1) NZ242775A (sh)
PL (1) PL170376B1 (sh)
SI (1) SI9200104A (sh)
TN (1) TNSN92049A1 (sh)
TW (1) TW218382B (sh)
WO (1) WO1992022553A1 (sh)
ZA (1) ZA924327B (sh)
ZM (1) ZM2892A1 (sh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
GR1001385B (el) * 1992-10-12 1993-10-29 Janssen Pharmaceutica Nv Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως.
ES2199224T3 (es) * 1992-12-04 2004-02-16 Janssen Pharmaceutica N.V. Derivados de imidazo(1,2-a)tieno(2,3-d)azepina antialergicos.
ATE194350T1 (de) * 1992-12-04 2000-07-15 Janssen Pharmaceutica Nv Antiallergisch triazolo (pyrrolo, thieno oder furano) azepinderivate
ES2155092T3 (es) * 1993-07-13 2001-05-01 Janssen Pharmaceutica Nv Imidazoazepinas antialergicas.
TW382017B (en) * 1995-12-27 2000-02-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
JP3882224B2 (ja) * 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
JP3775780B2 (ja) 1997-09-18 2006-05-17 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 薬剤の経口的バイオアベイラビリテイを向上させるための縮合イミダゾール誘導体
SI1144411T1 (en) 1998-12-19 2005-10-31 Janssen Pharmaceutica N.V. Antihistaminic spiro compounds
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
CN100491378C (zh) 2001-06-12 2009-05-27 詹森药业有限公司 新的取代四环咪唑衍生物,其制备方法,包含它们的药物组合物及它们作为药物的用途
AU2004259009A1 (en) * 2003-07-23 2005-02-03 Exelixis, Inc. Azepine derivatives as pharmaceutical agents
EP1858896B1 (en) 2005-03-08 2010-08-18 Janssen Pharmaceutica NV Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
CN103570731B (zh) * 2012-07-30 2016-05-18 中国科学院广州生物医药与健康研究院 嘧啶并三环或嘧啶并四环类化合物及其药用组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) * 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
AU652841B2 (en) 1994-09-08
HU9303554D0 (en) 1994-04-28
ATE247118T1 (de) 2003-08-15
TNSN92049A1 (fr) 1993-06-08
EP0588859A1 (en) 1994-03-30
TW218382B (sh) 1994-01-01
NO934493L (no) 1994-01-04
ES2204892T3 (es) 2004-05-01
HUT70428A (en) 1995-10-30
MX9202860A (es) 1992-12-01
WO1992022553A1 (en) 1992-12-23
FI935557A0 (fi) 1993-12-10
EP0518434A1 (en) 1992-12-16
NO300689B1 (no) 1997-07-07
IL101851A0 (en) 1992-12-30
HU221013B1 (hu) 2002-07-29
CN1033587C (zh) 1996-12-18
HRP920156A2 (en) 1995-12-31
ZA924327B (en) 1993-12-13
FI935557A (fi) 1993-12-10
CN1068116A (zh) 1993-01-20
NO934493D0 (no) 1993-12-09
NZ242775A (en) 1995-03-28
JP3182421B2 (ja) 2001-07-03
ZM2892A1 (en) 1994-05-25
DE69233161T2 (de) 2004-05-27
MA22554A1 (fr) 1992-12-31
IL101851A (en) 1996-05-14
AU1901192A (en) 1993-01-12
US5461050A (en) 1995-10-24
CA2102889A1 (en) 1992-12-14
IE921919A1 (en) 1992-12-16
FI104077B1 (fi) 1999-11-15
FI104077B (fi) 1999-11-15
JPH06507890A (ja) 1994-09-08
EP0588859B1 (en) 2003-08-13
DE69233161D1 (de) 2003-09-18
PL170376B1 (pl) 1996-12-31
CA2102889C (en) 2002-11-26
KR100247504B1 (ko) 2000-05-01

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Effective date: 20051013