SI9011538A - Novi 1-oksa-2-okso-8-azaspiro/4,5/dekanski derivati, farmacevtski pripravki, ki jih vsebujejo, in postopek za njihovo pripravo - Google Patents

Novi 1-oksa-2-okso-8-azaspiro/4,5/dekanski derivati, farmacevtski pripravki, ki jih vsebujejo, in postopek za njihovo pripravo Download PDF

Info

Publication number
SI9011538A
SI9011538A SI9011538A SI9011538A SI9011538A SI 9011538 A SI9011538 A SI 9011538A SI 9011538 A SI9011538 A SI 9011538A SI 9011538 A SI9011538 A SI 9011538A SI 9011538 A SI9011538 A SI 9011538A
Authority
SI
Slovenia
Prior art keywords
formula
group
oxo
defined above
oxa
Prior art date
Application number
SI9011538A
Other languages
English (en)
Slovenian (sl)
Inventor
Edit Toth
Jozsef Toerley
Laszlo Szporny
Bela Kiss
Egon Karpati
Eva Palosi
Dora Groo
Istvan Laszlovszky
Zsolt Szombathelyi
Adam Sarkadi
Aniko Gere
Katalin Csomor
Mihaly Bodo
Judit Laszy
Zsolt Szentirmay
Original Assignee
Richter Gedeon Vegyeszeti Gyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar Rt. filed Critical Richter Gedeon Vegyeszeti Gyar Rt.
Priority claimed from YU153890A external-priority patent/YU47748B/sh
Publication of SI9011538A publication Critical patent/SI9011538A/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
SI9011538A 1989-08-10 1990-08-09 Novi 1-oksa-2-okso-8-azaspiro/4,5/dekanski derivati, farmacevtski pripravki, ki jih vsebujejo, in postopek za njihovo pripravo SI9011538A (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU894095A HU204530B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
YU153890A YU47748B (sh) 1989-08-10 1990-08-09 1-oksa-2-okso-8-azaspiro(4,5)dekan derivati i postupak za njihovo dobijanje
SG96294A SG96294G (en) 1989-08-10 1994-07-16 1-oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
SI9011538A true SI9011538A (sl) 1998-08-31

Family

ID=26317733

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9011538A SI9011538A (sl) 1989-08-10 1990-08-09 Novi 1-oksa-2-okso-8-azaspiro/4,5/dekanski derivati, farmacevtski pripravki, ki jih vsebujejo, in postopek za njihovo pripravo

Country Status (23)

Country Link
US (1) US5118687A (pl)
EP (1) EP0414421B1 (pl)
JP (1) JPH0749431B2 (pl)
KR (1) KR940006635B1 (pl)
AT (1) ATE103920T1 (pl)
AU (1) AU622039B2 (pl)
BG (1) BG60436B2 (pl)
DD (1) DD299429A5 (pl)
DE (1) DE69007904T2 (pl)
DK (1) DK0414421T3 (pl)
ES (1) ES2052180T3 (pl)
FI (1) FI93455C (pl)
HK (1) HK145994A (pl)
HR (1) HRP920778A2 (pl)
HU (2) HU204530B (pl)
IE (1) IE64911B1 (pl)
IL (1) IL95320A (pl)
NO (1) NO177962C (pl)
NZ (1) NZ234848A (pl)
PL (3) PL163370B1 (pl)
SG (1) SG96294G (pl)
SI (1) SI9011538A (pl)
ZA (1) ZA906302B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
CA2386408A1 (en) * 1999-10-15 2001-04-26 Genetics Institute, Inc. Formulations of hyaluronic acid for delivery of osteogenic proteins
KR20020091462A (ko) * 2001-05-30 2002-12-06 삼성광주전자 주식회사 원료 굳음 방지기능을 갖는 자동판매기 및 그 제어방법
GB201416346D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR96352E (fr) * 1967-12-29 1972-06-16 Science Union & Cie Nouveaux dérives du spiro (4,5) decane et leur procédé de préparation.
BE790675A (fr) * 1971-10-29 1973-04-27 Science Union & Cie Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
HU204529B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물

Also Published As

Publication number Publication date
PL163593B1 (en) 1994-04-29
FI93455B (fi) 1994-12-30
AU622039B2 (en) 1992-03-26
NO177962C (no) 1995-12-27
EP0414421A3 (en) 1991-07-24
PL291701A1 (en) 1992-05-04
FI903972A0 (fi) 1990-08-10
NZ234848A (en) 1992-03-26
PL163431B1 (pl) 1994-03-31
NO903512L (no) 1991-02-11
IE64911B1 (en) 1995-09-20
EP0414421A2 (en) 1991-02-27
FI93455C (fi) 1995-04-10
KR940006635B1 (ko) 1994-07-23
PL291702A1 (en) 1992-05-04
PL286440A1 (en) 1992-01-27
IL95320A (en) 1994-01-25
IE902884A1 (en) 1991-02-27
DK0414421T3 (da) 1994-05-16
SG96294G (en) 1994-10-28
NO177962B (no) 1995-09-18
ZA906302B (en) 1991-06-26
DE69007904D1 (de) 1994-05-11
ATE103920T1 (de) 1994-04-15
HUT55786A (en) 1991-06-28
HU204530B (en) 1992-01-28
KR910004632A (ko) 1991-03-29
EP0414421B1 (en) 1994-04-06
JPH0377884A (ja) 1991-04-03
ES2052180T3 (es) 1994-07-01
HU210072A9 (en) 1995-02-28
NO903512D0 (no) 1990-08-09
BG60436B2 (bg) 1995-03-31
AU6080790A (en) 1991-02-14
HRP920778A2 (en) 1998-02-28
JPH0749431B2 (ja) 1995-05-31
DE69007904T2 (de) 1994-07-21
DD299429A5 (de) 1992-04-16
HK145994A (en) 1994-12-30
US5118687A (en) 1992-06-02
IL95320A0 (en) 1991-06-30
PL163370B1 (pl) 1994-03-31

Similar Documents

Publication Publication Date Title
AU701452B2 (en) Benzylpiperidines and piperazines as muscarinic antagonists
EP0258755B1 (en) Alpha-alkyl-4-amino-3-quinoline-methanols and 1-(4-aralkylamino-3-quinolinyl) alkanones, a process for their preparation and their use as medicaments
US4500525A (en) Pharmacologically active pyrazolo/4,3-c/pyridines
EP0040639A1 (en) Isoxazole derivatives
HU198931B (en) Process for producing 2-square brackets open /piperidin-4-yl/-methyl square brackets closed -1,2,3,4-tetradihydro-9h-pyrido/3,4-b/indole derivatives and pharma ceutical compositions comprising same
DE60307875T2 (de) Imidazopyrin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusamensetzungen
HU204276B (en) Process for producing new 1-oxa-2-oxo-4-methylen-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
DE602005006018T2 (de) Arylpiperazinderivate und deren verwendung als für den dopamin-d3-rezeptor selektive liganden
DE69736890T2 (de) Kondensierte heterozyklische verbindungen und ihre pharmazeutische anwendung
EP0964863A1 (de) Oxazolidinone als 5-ht2a-antagonisten
JPH0517904B2 (pl)
EP0414422A2 (en) 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
DD149069A5 (de) Verfahren zur herstellung neuer piperidinopropylerivate
EP0412822B1 (en) 4,4-Disubstituted piperidine derivatives, processes for their preparation and pharmaceutical compositions thereof
DK166584B1 (da) Substituerede 4-benzyl-1h-imidazoler, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende dem
SI9011538A (sl) Novi 1-oksa-2-okso-8-azaspiro/4,5/dekanski derivati, farmacevtski pripravki, ki jih vsebujejo, in postopek za njihovo pripravo
HUT70148A (en) Isoquinolone derivatives as techykinin receptor antagonists, process for producing thereof and pharmaceutical compositions comprising them
HU204054B (en) Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same
JP2001512731A (ja) AMPA/Kainate受容体阻害剤としての1,3−ジオキソロ/4,5−H/2,3/ベンゾジアゼピン誘導体
US4277470A (en) Heterocyclic spiro-linked amidines, compositions and use thereof
US4318909A (en) Benzoxazocines
JPH04217945A (ja) 置換アルキルベンゼン誘導体およびそれを含有する抗潰瘍剤
CA2023019A1 (en) 1-oxa-2-oxo-8-azaspiro/4,5/decane derivatives, pharmaceutical compositions containing them and process for preparing the same
US3591594A (en) Substituted 6,7-dihydro-indole-4-(5h)-one
EP0318166A2 (en) Isoxazolo[4,5-c]azepine derivatives, process for their preparation and pharmaceutical compositions containing them