SI3542817T1 - Virus humane imunske pomanjkljivosti(HIV) - nevtralizirajoča protitelesa - Google Patents
Virus humane imunske pomanjkljivosti(HIV) - nevtralizirajoča protitelesaInfo
- Publication number
- SI3542817T1 SI3542817T1 SI201032112T SI201032112T SI3542817T1 SI 3542817 T1 SI3542817 T1 SI 3542817T1 SI 201032112 T SI201032112 T SI 201032112T SI 201032112 T SI201032112 T SI 201032112T SI 3542817 T1 SI3542817 T1 SI 3542817T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hiv
- immunodeficiency virus
- human immunodeficiency
- neutralizing antibodies
- neutralizing
- Prior art date
Links
- 241000725303 Human immunodeficiency virus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16101009P | 2009-03-17 | 2009-03-17 | |
US16582909P | 2009-04-01 | 2009-04-01 | |
US22473909P | 2009-07-10 | 2009-07-10 | |
US28566409P | 2009-12-11 | 2009-12-11 | |
EP18207707.3A EP3542817B1 (en) | 2009-03-17 | 2010-03-17 | Human immunodeficiency virus (hiv)-neutralizing antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3542817T1 true SI3542817T1 (sl) | 2022-09-30 |
Family
ID=42668183
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201032049T SI3260136T1 (sl) | 2009-03-17 | 2010-03-01 | Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa |
SI201032112T SI3542817T1 (sl) | 2009-03-17 | 2010-03-17 | Virus humane imunske pomanjkljivosti(HIV) - nevtralizirajoča protitelesa |
SI201031616T SI2408476T1 (sl) | 2009-03-17 | 2010-03-17 | Humani imunodificientni virus (hiv)-nevtralizirajoča protitelesa |
SI201032062T SI3323427T1 (sl) | 2009-03-17 | 2010-03-17 | Protitelesa, ki nevtralizirajo virus humane imunske pomanjkljivosti (HIV) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201032049T SI3260136T1 (sl) | 2009-03-17 | 2010-03-01 | Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201031616T SI2408476T1 (sl) | 2009-03-17 | 2010-03-17 | Humani imunodificientni virus (hiv)-nevtralizirajoča protitelesa |
SI201032062T SI3323427T1 (sl) | 2009-03-17 | 2010-03-17 | Protitelesa, ki nevtralizirajo virus humane imunske pomanjkljivosti (HIV) |
Country Status (15)
Country | Link |
---|---|
US (7) | US9051362B2 (sl) |
EP (5) | EP2408476B1 (sl) |
AU (5) | AU2010226668B2 (sl) |
CA (2) | CA2755821C (sl) |
CY (1) | CY1121323T1 (sl) |
DK (1) | DK2408476T3 (sl) |
ES (4) | ES2848555T3 (sl) |
HR (1) | HRP20180027T1 (sl) |
HU (1) | HUE036031T2 (sl) |
LT (1) | LT2408476T (sl) |
NO (1) | NO2408476T3 (sl) |
PL (4) | PL3542817T3 (sl) |
PT (4) | PT2408476T (sl) |
SI (4) | SI3260136T1 (sl) |
WO (1) | WO2010107939A2 (sl) |
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WO2012040562A2 (en) | 2010-09-24 | 2012-03-29 | International Aids Vaccine Initiative | Novel hiv-1 broadly neutralizing antibodies |
EP2492279A1 (en) | 2011-02-25 | 2012-08-29 | Laboratorios Del. Dr. Esteve, S.A. | Rapid immunogen selection method using lentiviral display |
US10040826B2 (en) | 2011-07-05 | 2018-08-07 | Duke University | Human immunodeficiency virus type 1 (HIV-1) N-terminal deleted GP120 immunogens |
US8791108B2 (en) * | 2011-08-18 | 2014-07-29 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
US20140348865A1 (en) | 2011-09-12 | 2014-11-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Ser. | Immunogens based on an hiv-1 v1v2 site-of-vulnerability |
EP2763699A4 (en) * | 2011-10-03 | 2015-05-20 | Univ Duke | VACCINE |
US9988424B2 (en) | 2011-12-05 | 2018-06-05 | Duke University | Immunogens comprising human immunodeficiency virus V1/V2 polypeptides |
CN108676091B (zh) | 2011-12-08 | 2022-04-01 | 美国政府(由卫生和人类服务部的部长所代表) | Hiv-1的中和抗体及其用途 |
US20150044137A1 (en) * | 2012-03-23 | 2015-02-12 | The United States of America, as represented by the Secretary, Dep. of Health Care Human Services | Neutralizing antibodies to hiv-1 and their use |
EP2698377A1 (en) | 2012-08-17 | 2014-02-19 | Laboratorios Del. Dr. Esteve, S.A. | Enhanced rapid immunogen selection method for HIV gp120 variants |
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US20160130328A1 (en) * | 2013-06-17 | 2016-05-12 | Emory University | Pathogen Binding Agents Conjugated to Radioisotopes and Uses in Imaging and Therapeutic Applications |
WO2015048517A1 (en) * | 2013-09-28 | 2015-04-02 | Duke University | Escape mutants |
WO2015127108A1 (en) * | 2014-02-19 | 2015-08-27 | Duke University | Trimeric hiv-1 envelopes compositions and uses thereof |
US10093720B2 (en) * | 2014-06-11 | 2018-10-09 | International Aids Vaccine Initiative | Broadly neutralizing antibody and uses thereof |
PL3166607T3 (pl) | 2014-07-11 | 2023-02-20 | Gilead Sciences, Inc. | Modulatory receptorów toll-podobnych do leczenia hiv |
CN106715431A (zh) | 2014-09-16 | 2017-05-24 | 吉利德科学公司 | Toll样受体调节剂的固体形式 |
WO2016054023A1 (en) * | 2014-09-29 | 2016-04-07 | Duke University | Hiv-1 antibodies and uses thereof (adcc and bispecific abs) |
MA42818A (fr) | 2015-09-15 | 2018-07-25 | Gilead Sciences Inc | Modulateurs de récepteurs de type toll pour le traitement du vih |
BR112018005931A2 (pt) | 2015-09-24 | 2018-10-09 | Abvitro Llc | composições de anticorpo para hiv e métodos de uso |
WO2017106346A2 (en) | 2015-12-15 | 2017-06-22 | Gilead Sciences, Inc. | Human immunodeficiency virus neutralizing antibodies |
CN107022027B (zh) * | 2016-02-02 | 2022-03-08 | 中国疾病预防控制中心性病艾滋病预防控制中心 | Hiv-1广谱中和抗体及其用途 |
CN107033241B (zh) * | 2016-02-03 | 2022-03-08 | 中国疾病预防控制中心性病艾滋病预防控制中心 | Hiv-1广谱中和抗体及其用途 |
EP3642229A1 (en) | 2017-06-21 | 2020-04-29 | Gilead Sciences, Inc. | Multispecific antibodies that target hiv gp120 and cd3 |
EP3641806A4 (en) * | 2017-06-22 | 2021-06-23 | University of Maryland, Baltimore | BROAD NEUTRALIZING ANTIBODIES AGAINST HIV |
JP7126573B2 (ja) | 2018-07-03 | 2022-08-26 | ギリアード サイエンシーズ, インコーポレイテッド | HIV gp120を標的化する抗体および使用方法 |
WO2020082045A1 (en) * | 2018-10-19 | 2020-04-23 | University Of Maryland, College Park | Multispecfic anti-hiv antibodies |
CA3145791A1 (en) | 2019-07-16 | 2021-01-21 | Gilead Sciences, Inc. | Hiv vaccines and methods of making and using |
US20230134571A1 (en) * | 2019-10-29 | 2023-05-04 | International Aids Vaccine Initiative | Engineered antibodies to hiv env |
US20210277093A1 (en) * | 2020-03-09 | 2021-09-09 | Adma Biologics, Inc. | Immunotherapeutic compositions and methods of production for coronavirus |
JP2023539196A (ja) | 2020-08-25 | 2023-09-13 | ギリアード サイエンシーズ, インコーポレイテッド | Hivを標的とする多重特異性抗原結合分子及び使用方法 |
TW202406932A (zh) | 2020-10-22 | 2024-02-16 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
WO2022162009A1 (en) | 2021-01-26 | 2022-08-04 | Eth Zurich | Method for rapid identification of cross-reactive and/or rare antibodies |
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WO2022225875A1 (en) * | 2021-04-19 | 2022-10-27 | The Wistar Institute Of Anatomy And Biology | Sialydase linked hiv antibodies and methods of use |
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