SI3380467T1 - Heterociklični indoli za uporabo v okužbi z virusom gripe - Google Patents
Heterociklični indoli za uporabo v okužbi z virusom gripeInfo
- Publication number
- SI3380467T1 SI3380467T1 SI201631276T SI201631276T SI3380467T1 SI 3380467 T1 SI3380467 T1 SI 3380467T1 SI 201631276 T SI201631276 T SI 201631276T SI 201631276 T SI201631276 T SI 201631276T SI 3380467 T1 SI3380467 T1 SI 3380467T1
- Authority
- SI
- Slovenia
- Prior art keywords
- influenza virus
- virus infection
- indoles
- heterocyclic
- heterocyclic indoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15196811 | 2015-11-27 | ||
| PCT/EP2016/078778 WO2017089518A1 (en) | 2015-11-27 | 2016-11-25 | Heterocyclic indoles for use in influenza virus infection |
| EP16801246.6A EP3380467B1 (en) | 2015-11-27 | 2016-11-25 | Heterocyclic indoles for use in influenza virus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3380467T1 true SI3380467T1 (sl) | 2021-08-31 |
Family
ID=54707665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201631276T SI3380467T1 (sl) | 2015-11-27 | 2016-11-25 | Heterociklični indoli za uporabo v okužbi z virusom gripe |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10626108B2 (sl) |
| EP (1) | EP3380467B1 (sl) |
| JP (1) | JP6903658B2 (sl) |
| KR (1) | KR20180087290A (sl) |
| CN (1) | CN108290869B (sl) |
| AU (1) | AU2016359907B2 (sl) |
| CA (1) | CA3005514A1 (sl) |
| DK (1) | DK3380467T3 (sl) |
| EA (1) | EA201891278A1 (sl) |
| ES (1) | ES2882671T3 (sl) |
| HR (1) | HRP20211223T1 (sl) |
| HU (1) | HUE055200T2 (sl) |
| LT (1) | LT3380467T (sl) |
| MA (1) | MA43298A (sl) |
| SI (1) | SI3380467T1 (sl) |
| WO (1) | WO2017089518A1 (sl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ619259A (en) | 2009-06-17 | 2015-07-31 | Vertex Pharma | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| MA42422A (fr) | 2015-05-13 | 2018-05-23 | Vertex Pharma | Inhibiteurs de la réplication des virus de la grippe |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| LT3405466T (lt) | 2016-01-20 | 2021-01-25 | Janssen Sciences Ireland Unlimited Company | Arilu pakeistieji pirimidinai, skirti naudoti gripo viruso infekcijos atveju |
| US10501444B2 (en) | 2016-08-16 | 2019-12-10 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| US10647693B2 (en) | 2016-08-30 | 2020-05-12 | North & South Brother Pharmacy Investment Company Limited | Inhibitors of influenza virus replication, application methods and uses thereof |
| WO2018108125A1 (en) | 2016-12-15 | 2018-06-21 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| JP7299837B2 (ja) * | 2016-12-23 | 2023-06-28 | アクイナ ファーマシューティカルズ， インコーポレイテッド | 化合物、組成物、および使用方法 |
| US11098042B2 (en) | 2017-01-05 | 2021-08-24 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CN110446711B (zh) | 2017-03-02 | 2022-02-15 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ567133A (en) | 2005-09-30 | 2011-07-29 | Vertex Pharma | Deazapurines useful as inhibitors of janus kinases |
| CA2659582A1 (en) * | 2006-06-22 | 2007-12-27 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| RU2481340C2 (ru) | 2007-02-08 | 2013-05-10 | Тиботек Фармасьютикалз Лтд. | Пиримидин-замещенные макроциклические ингибиторы hcv |
| NZ619259A (en) | 2009-06-17 | 2015-07-31 | Vertex Pharma | Inhibitors of influenza viruses replication |
| ES2602972T3 (es) | 2010-09-08 | 2017-02-23 | Glaxosmithkline Intellectual Property Development Limited | Derivados de indazol para su uso en el tratamiento de infección por virus de la gripe |
| CN103562205A (zh) * | 2010-12-16 | 2014-02-05 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
| JP2013545816A (ja) | 2010-12-16 | 2013-12-26 | バーテックス ファーマシューティカルズ インコーポレイテッド | インフルエンザウイルス複製阻害物質 |
| ES2691745T3 (es) | 2011-04-08 | 2018-11-28 | Janssen Sciences Ireland Uc | Derivados de pirimidina para el tratamiento de infecciones víricas |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EP2858984A1 (en) | 2012-06-08 | 2015-04-15 | Vertex Pharmaceuticals Inc. | Inhibitors of influenza viruses replication |
| ME02835B (me) | 2012-10-16 | 2018-01-20 | Janssen Sciences Ireland Uc | Antivirusna rsv jedinjenja |
| JP6404835B2 (ja) | 2013-02-21 | 2018-10-17 | ヤンセン・サイエンシズ・アイルランド・ユーシー | ウイルス感染の治療のための２−アミノピリミジン誘導体 |
| LT3405466T (lt) | 2016-01-20 | 2021-01-25 | Janssen Sciences Ireland Unlimited Company | Arilu pakeistieji pirimidinai, skirti naudoti gripo viruso infekcijos atveju |
-
2016
- 2016-11-25 AU AU2016359907A patent/AU2016359907B2/en active Active
- 2016-11-25 JP JP2018527221A patent/JP6903658B2/ja active Active
- 2016-11-25 US US15/779,468 patent/US10626108B2/en active Active
- 2016-11-25 DK DK16801246.6T patent/DK3380467T3/da active
- 2016-11-25 CN CN201680068994.8A patent/CN108290869B/zh active Active
- 2016-11-25 EP EP16801246.6A patent/EP3380467B1/en active Active
- 2016-11-25 MA MA043298A patent/MA43298A/fr unknown
- 2016-11-25 KR KR1020187016921A patent/KR20180087290A/ko not_active Application Discontinuation
- 2016-11-25 ES ES16801246T patent/ES2882671T3/es active Active
- 2016-11-25 CA CA3005514A patent/CA3005514A1/en active Pending
- 2016-11-25 HU HUE16801246A patent/HUE055200T2/hu unknown
- 2016-11-25 EA EA201891278A patent/EA201891278A1/ru unknown
- 2016-11-25 WO PCT/EP2016/078778 patent/WO2017089518A1/en active Application Filing
- 2016-11-25 SI SI201631276T patent/SI3380467T1/sl unknown
- 2016-11-25 LT LTEPPCT/EP2016/078778T patent/LT3380467T/lt unknown
-
2021
- 2021-07-29 HR HRP20211223TT patent/HRP20211223T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LT3380467T (lt) | 2021-08-10 |
| JP2019501879A (ja) | 2019-01-24 |
| KR20180087290A (ko) | 2018-08-01 |
| EA201891278A1 (ru) | 2018-11-30 |
| AU2016359907B2 (en) | 2021-04-01 |
| DK3380467T3 (da) | 2021-09-27 |
| MA43298A (fr) | 2021-04-14 |
| US20180258074A1 (en) | 2018-09-13 |
| WO2017089518A1 (en) | 2017-06-01 |
| HUE055200T2 (hu) | 2021-11-29 |
| AU2016359907A1 (en) | 2018-05-24 |
| CN108290869A (zh) | 2018-07-17 |
| US10626108B2 (en) | 2020-04-21 |
| EP3380467A1 (en) | 2018-10-03 |
| EP3380467B1 (en) | 2021-07-07 |
| JP6903658B2 (ja) | 2021-07-14 |
| CN108290869B (zh) | 2021-05-18 |
| CA3005514A1 (en) | 2017-06-01 |
| ES2882671T3 (es) | 2021-12-02 |
| HRP20211223T1 (hr) | 2021-11-12 |
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