SI3097085T1 - Derivati benzoksazinona za zdravljenje kožnih bolezni - Google Patents

Derivati benzoksazinona za zdravljenje kožnih bolezni

Info

Publication number
SI3097085T1
SI3097085T1 SI201531393T SI201531393T SI3097085T1 SI 3097085 T1 SI3097085 T1 SI 3097085T1 SI 201531393 T SI201531393 T SI 201531393T SI 201531393 T SI201531393 T SI 201531393T SI 3097085 T1 SI3097085 T1 SI 3097085T1
Authority
SI
Slovenia
Prior art keywords
treatment
skin diseases
benzoxazinone derivatives
benzoxazinone
derivatives
Prior art date
Application number
SI201531393T
Other languages
English (en)
Slovenian (sl)
Inventor
Fredrik Wagberg
Goran Leonardsson
Original Assignee
Sixera Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sixera Pharma Ab filed Critical Sixera Pharma Ab
Publication of SI3097085T1 publication Critical patent/SI3097085T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/539Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more oxygen atoms in the same ring, e.g. dioxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI201531393T 2014-01-23 2015-01-22 Derivati benzoksazinona za zdravljenje kožnih bolezni SI3097085T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1430003 2014-01-23
EP15740572.1A EP3097085B1 (en) 2014-01-23 2015-01-22 Benzoxazinone derivatives for treatment of skin diseases
PCT/SE2015/050062 WO2015112081A1 (en) 2014-01-23 2015-01-22 Benzoxazinone derivatives for treatment of skin diseases

Publications (1)

Publication Number Publication Date
SI3097085T1 true SI3097085T1 (sl) 2020-11-30

Family

ID=53681747

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201531393T SI3097085T1 (sl) 2014-01-23 2015-01-22 Derivati benzoksazinona za zdravljenje kožnih bolezni

Country Status (18)

Country Link
US (2) US9695194B2 (OSRAM)
EP (1) EP3097085B1 (OSRAM)
JP (1) JP6448651B2 (OSRAM)
CN (1) CN106132941B (OSRAM)
AU (1) AU2015209761B2 (OSRAM)
CA (1) CA2934025C (OSRAM)
CY (1) CY1123477T1 (OSRAM)
DK (1) DK3097085T3 (OSRAM)
ES (1) ES2820868T3 (OSRAM)
HR (1) HRP20201500T1 (OSRAM)
HU (1) HUE051296T2 (OSRAM)
LT (1) LT3097085T (OSRAM)
PL (1) PL3097085T3 (OSRAM)
PT (1) PT3097085T (OSRAM)
RS (1) RS60830B1 (OSRAM)
SI (1) SI3097085T1 (OSRAM)
SM (1) SMT202000557T1 (OSRAM)
WO (1) WO2015112081A1 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3097085T (lt) * 2014-01-23 2020-10-12 Sixera Pharma Ab Benzoksazinono dariniai, skirti odos ligų gydymui
EP3296291B1 (en) * 2015-05-13 2022-06-08 Nihon Nohyaku Co., Ltd. Anthranilate compound, salt thereof, horticultural fungicide containing said compound, and a method for use thereof
EP3402572B1 (en) * 2016-01-13 2022-03-16 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
CA3067364A1 (en) * 2017-06-16 2018-12-20 Azitra Inc Compositions and methods for treatment of netherton syndrome with lekti expressing recombinant microbes
US20200040103A1 (en) 2018-03-14 2020-02-06 Genentech, Inc. Anti-klk5 antibodies and methods of use
US12360103B2 (en) 2018-04-20 2025-07-15 Children's Hospital Medical Center Blood biomarker for eosinophilic gastrointestinal disorders
GB201809378D0 (en) 2018-06-07 2018-07-25 Glaxosmithkline Ip Dev Ltd Novel compounds
US12297501B2 (en) 2019-02-25 2025-05-13 Children's Hospital Medical Center Methods for diagnosing and treating eosinophilic gastritis
CR20220156A (es) 2019-09-18 2022-05-23 Genentech Inc Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5/klk7 y métodos de uso
JP2022551583A (ja) * 2019-10-01 2022-12-12 モレキュラー スキン セラピューティクス,インコーポレイティド Klk5/7デュアル阻害剤としてのベンゾキサジノン化合物
GB202001447D0 (en) * 2020-02-03 2020-03-18 Ucb Biopharma Sprl Antibodies
BR102020009679A2 (pt) 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
TW202304890A (zh) * 2021-04-14 2023-02-01 美商百歐克斯製藥公司 Klk5雙環雜芳香族抑制劑
WO2022253911A1 (en) 2021-06-01 2022-12-08 Sixera Pharma Ab Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB115399A (en) * 1917-03-28 1918-04-29 Reginald Guley Lewis Improved Delivery mechanism for Coin-freed Apparatus and the like.
GB1153994A (en) * 1965-07-21 1969-06-04 Aspro Nicholas Ltd Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them
WO1999048878A1 (en) * 1998-03-24 1999-09-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
JP5044214B2 (ja) 2003-06-06 2012-10-10 アレクシス・アクチボラゲット 皮膚状態または癌の処置のためのscce阻害剤としての縮合複素環化合物の使用
TWI419884B (zh) 2010-06-24 2013-12-21 Univ Chang Gung 苯并雜氧嗪酮衍生物,其製備方法以及包含有此等衍生物的藥學組成物
LT3097085T (lt) * 2014-01-23 2020-10-12 Sixera Pharma Ab Benzoksazinono dariniai, skirti odos ligų gydymui

Also Published As

Publication number Publication date
CN106132941A (zh) 2016-11-16
EP3097085B1 (en) 2020-07-29
CY1123477T1 (el) 2022-03-24
US9695194B2 (en) 2017-07-04
SMT202000557T1 (it) 2020-11-10
AU2015209761A1 (en) 2016-07-07
RS60830B1 (sr) 2020-10-30
CA2934025A1 (en) 2015-07-30
HRP20201500T1 (hr) 2020-12-25
JP6448651B2 (ja) 2019-01-09
US20170267692A1 (en) 2017-09-21
LT3097085T (lt) 2020-10-12
PT3097085T (pt) 2020-10-08
US10072024B2 (en) 2018-09-11
CN106132941B (zh) 2018-04-06
EP3097085A4 (en) 2017-08-09
EP3097085A1 (en) 2016-11-30
HUE051296T2 (hu) 2021-03-01
JP2017503798A (ja) 2017-02-02
CA2934025C (en) 2022-06-07
AU2015209761B2 (en) 2018-11-29
ES2820868T3 (es) 2021-04-22
DK3097085T3 (da) 2020-10-26
US20170002021A1 (en) 2017-01-05
PL3097085T3 (pl) 2021-01-11
WO2015112081A1 (en) 2015-07-30

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