PT3097085T - Derivados de benzoxazinona para tratamento de doenças de pele - Google Patents
Derivados de benzoxazinona para tratamento de doenças de peleInfo
- Publication number
- PT3097085T PT3097085T PT157405721T PT15740572T PT3097085T PT 3097085 T PT3097085 T PT 3097085T PT 157405721 T PT157405721 T PT 157405721T PT 15740572 T PT15740572 T PT 15740572T PT 3097085 T PT3097085 T PT 3097085T
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- skin diseases
- benzoxazinone derivatives
- benzoxazinone
- derivatives
- Prior art date
Links
- HQQTZCPKNZVLFF-UHFFFAOYSA-N 4h-1,2-benzoxazin-3-one Chemical class C1=CC=C2ONC(=O)CC2=C1 HQQTZCPKNZVLFF-UHFFFAOYSA-N 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/539—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more oxygen atoms in the same ring, e.g. dioxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1430003 | 2014-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3097085T true PT3097085T (pt) | 2020-10-08 |
Family
ID=53681747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157405721T PT3097085T (pt) | 2014-01-23 | 2015-01-22 | Derivados de benzoxazinona para tratamento de doenças de pele |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9695194B2 (OSRAM) |
| EP (1) | EP3097085B1 (OSRAM) |
| JP (1) | JP6448651B2 (OSRAM) |
| CN (1) | CN106132941B (OSRAM) |
| AU (1) | AU2015209761B2 (OSRAM) |
| CA (1) | CA2934025C (OSRAM) |
| CY (1) | CY1123477T1 (OSRAM) |
| DK (1) | DK3097085T3 (OSRAM) |
| ES (1) | ES2820868T3 (OSRAM) |
| HR (1) | HRP20201500T1 (OSRAM) |
| HU (1) | HUE051296T2 (OSRAM) |
| LT (1) | LT3097085T (OSRAM) |
| PL (1) | PL3097085T3 (OSRAM) |
| PT (1) | PT3097085T (OSRAM) |
| RS (1) | RS60830B1 (OSRAM) |
| SI (1) | SI3097085T1 (OSRAM) |
| SM (1) | SMT202000557T1 (OSRAM) |
| WO (1) | WO2015112081A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3097085T (lt) * | 2014-01-23 | 2020-10-12 | Sixera Pharma Ab | Benzoksazinono dariniai, skirti odos ligų gydymui |
| EP3296291B1 (en) * | 2015-05-13 | 2022-06-08 | Nihon Nohyaku Co., Ltd. | Anthranilate compound, salt thereof, horticultural fungicide containing said compound, and a method for use thereof |
| EP3402572B1 (en) * | 2016-01-13 | 2022-03-16 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
| CA3067364A1 (en) * | 2017-06-16 | 2018-12-20 | Azitra Inc | Compositions and methods for treatment of netherton syndrome with lekti expressing recombinant microbes |
| US20200040103A1 (en) | 2018-03-14 | 2020-02-06 | Genentech, Inc. | Anti-klk5 antibodies and methods of use |
| US12360103B2 (en) | 2018-04-20 | 2025-07-15 | Children's Hospital Medical Center | Blood biomarker for eosinophilic gastrointestinal disorders |
| GB201809378D0 (en) | 2018-06-07 | 2018-07-25 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US12297501B2 (en) | 2019-02-25 | 2025-05-13 | Children's Hospital Medical Center | Methods for diagnosing and treating eosinophilic gastritis |
| CR20220156A (es) | 2019-09-18 | 2022-05-23 | Genentech Inc | Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5/klk7 y métodos de uso |
| JP2022551583A (ja) * | 2019-10-01 | 2022-12-12 | モレキュラー スキン セラピューティクス,インコーポレイティド | Klk5/7デュアル阻害剤としてのベンゾキサジノン化合物 |
| GB202001447D0 (en) * | 2020-02-03 | 2020-03-18 | Ucb Biopharma Sprl | Antibodies |
| BR102020009679A2 (pt) | 2020-05-14 | 2021-11-23 | Fundação Universidade Federal Do Abc - Ufabc | Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele |
| TW202304890A (zh) * | 2021-04-14 | 2023-02-01 | 美商百歐克斯製藥公司 | Klk5雙環雜芳香族抑制劑 |
| WO2022253911A1 (en) | 2021-06-01 | 2022-12-08 | Sixera Pharma Ab | Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB115399A (en) * | 1917-03-28 | 1918-04-29 | Reginald Guley Lewis | Improved Delivery mechanism for Coin-freed Apparatus and the like. |
| GB1153994A (en) * | 1965-07-21 | 1969-06-04 | Aspro Nicholas Ltd | Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them |
| WO1999048878A1 (en) * | 1998-03-24 | 1999-09-30 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| JP5044214B2 (ja) | 2003-06-06 | 2012-10-10 | アレクシス・アクチボラゲット | 皮膚状態または癌の処置のためのscce阻害剤としての縮合複素環化合物の使用 |
| TWI419884B (zh) | 2010-06-24 | 2013-12-21 | Univ Chang Gung | 苯并雜氧嗪酮衍生物,其製備方法以及包含有此等衍生物的藥學組成物 |
| LT3097085T (lt) * | 2014-01-23 | 2020-10-12 | Sixera Pharma Ab | Benzoksazinono dariniai, skirti odos ligų gydymui |
-
2015
- 2015-01-22 LT LTEP15740572.1T patent/LT3097085T/lt unknown
- 2015-01-22 AU AU2015209761A patent/AU2015209761B2/en active Active
- 2015-01-22 RS RS20201128A patent/RS60830B1/sr unknown
- 2015-01-22 CA CA2934025A patent/CA2934025C/en active Active
- 2015-01-22 PT PT157405721T patent/PT3097085T/pt unknown
- 2015-01-22 SI SI201531393T patent/SI3097085T1/sl unknown
- 2015-01-22 JP JP2016544672A patent/JP6448651B2/ja active Active
- 2015-01-22 US US15/113,750 patent/US9695194B2/en active Active
- 2015-01-22 CN CN201580005383.4A patent/CN106132941B/zh active Active
- 2015-01-22 DK DK15740572.1T patent/DK3097085T3/da active
- 2015-01-22 HR HRP20201500TT patent/HRP20201500T1/hr unknown
- 2015-01-22 EP EP15740572.1A patent/EP3097085B1/en active Active
- 2015-01-22 HU HUE15740572A patent/HUE051296T2/hu unknown
- 2015-01-22 PL PL15740572T patent/PL3097085T3/pl unknown
- 2015-01-22 ES ES15740572T patent/ES2820868T3/es active Active
- 2015-01-22 SM SM20200557T patent/SMT202000557T1/it unknown
- 2015-01-22 WO PCT/SE2015/050062 patent/WO2015112081A1/en not_active Ceased
-
2017
- 2017-06-05 US US15/614,462 patent/US10072024B2/en active Active
-
2020
- 2020-10-20 CY CY20201100988T patent/CY1123477T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN106132941A (zh) | 2016-11-16 |
| EP3097085B1 (en) | 2020-07-29 |
| CY1123477T1 (el) | 2022-03-24 |
| US9695194B2 (en) | 2017-07-04 |
| SMT202000557T1 (it) | 2020-11-10 |
| AU2015209761A1 (en) | 2016-07-07 |
| RS60830B1 (sr) | 2020-10-30 |
| CA2934025A1 (en) | 2015-07-30 |
| HRP20201500T1 (hr) | 2020-12-25 |
| JP6448651B2 (ja) | 2019-01-09 |
| US20170267692A1 (en) | 2017-09-21 |
| LT3097085T (lt) | 2020-10-12 |
| US10072024B2 (en) | 2018-09-11 |
| CN106132941B (zh) | 2018-04-06 |
| EP3097085A4 (en) | 2017-08-09 |
| SI3097085T1 (sl) | 2020-11-30 |
| EP3097085A1 (en) | 2016-11-30 |
| HUE051296T2 (hu) | 2021-03-01 |
| JP2017503798A (ja) | 2017-02-02 |
| CA2934025C (en) | 2022-06-07 |
| AU2015209761B2 (en) | 2018-11-29 |
| ES2820868T3 (es) | 2021-04-22 |
| DK3097085T3 (da) | 2020-10-26 |
| US20170002021A1 (en) | 2017-01-05 |
| PL3097085T3 (pl) | 2021-01-11 |
| WO2015112081A1 (en) | 2015-07-30 |
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