PT3097085T - Derivados de benzoxazinona para tratamento de doenças de pele - Google Patents

Derivados de benzoxazinona para tratamento de doenças de pele

Info

Publication number
PT3097085T
PT3097085T PT157405721T PT15740572T PT3097085T PT 3097085 T PT3097085 T PT 3097085T PT 157405721 T PT157405721 T PT 157405721T PT 15740572 T PT15740572 T PT 15740572T PT 3097085 T PT3097085 T PT 3097085T
Authority
PT
Portugal
Prior art keywords
treatment
skin diseases
benzoxazinone derivatives
benzoxazinone
derivatives
Prior art date
Application number
PT157405721T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Sixera Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sixera Pharma Ab filed Critical Sixera Pharma Ab
Publication of PT3097085T publication Critical patent/PT3097085T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/539Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more oxygen atoms in the same ring, e.g. dioxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT157405721T 2014-01-23 2015-01-22 Derivados de benzoxazinona para tratamento de doenças de pele PT3097085T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE1430003 2014-01-23

Publications (1)

Publication Number Publication Date
PT3097085T true PT3097085T (pt) 2020-10-08

Family

ID=53681747

Family Applications (1)

Application Number Title Priority Date Filing Date
PT157405721T PT3097085T (pt) 2014-01-23 2015-01-22 Derivados de benzoxazinona para tratamento de doenças de pele

Country Status (18)

Country Link
US (2) US9695194B2 (OSRAM)
EP (1) EP3097085B1 (OSRAM)
JP (1) JP6448651B2 (OSRAM)
CN (1) CN106132941B (OSRAM)
AU (1) AU2015209761B2 (OSRAM)
CA (1) CA2934025C (OSRAM)
CY (1) CY1123477T1 (OSRAM)
DK (1) DK3097085T3 (OSRAM)
ES (1) ES2820868T3 (OSRAM)
HR (1) HRP20201500T1 (OSRAM)
HU (1) HUE051296T2 (OSRAM)
LT (1) LT3097085T (OSRAM)
PL (1) PL3097085T3 (OSRAM)
PT (1) PT3097085T (OSRAM)
RS (1) RS60830B1 (OSRAM)
SI (1) SI3097085T1 (OSRAM)
SM (1) SMT202000557T1 (OSRAM)
WO (1) WO2015112081A1 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3097085T (lt) * 2014-01-23 2020-10-12 Sixera Pharma Ab Benzoksazinono dariniai, skirti odos ligų gydymui
EP3296291B1 (en) * 2015-05-13 2022-06-08 Nihon Nohyaku Co., Ltd. Anthranilate compound, salt thereof, horticultural fungicide containing said compound, and a method for use thereof
EP3402572B1 (en) * 2016-01-13 2022-03-16 Children's Hospital Medical Center Compositions and methods for treating allergic inflammatory conditions
CA3067364A1 (en) * 2017-06-16 2018-12-20 Azitra Inc Compositions and methods for treatment of netherton syndrome with lekti expressing recombinant microbes
US20200040103A1 (en) 2018-03-14 2020-02-06 Genentech, Inc. Anti-klk5 antibodies and methods of use
US12360103B2 (en) 2018-04-20 2025-07-15 Children's Hospital Medical Center Blood biomarker for eosinophilic gastrointestinal disorders
GB201809378D0 (en) 2018-06-07 2018-07-25 Glaxosmithkline Ip Dev Ltd Novel compounds
US12297501B2 (en) 2019-02-25 2025-05-13 Children's Hospital Medical Center Methods for diagnosing and treating eosinophilic gastritis
CR20220156A (es) 2019-09-18 2022-05-23 Genentech Inc Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5/klk7 y métodos de uso
JP2022551583A (ja) * 2019-10-01 2022-12-12 モレキュラー スキン セラピューティクス,インコーポレイティド Klk5/7デュアル阻害剤としてのベンゾキサジノン化合物
GB202001447D0 (en) * 2020-02-03 2020-03-18 Ucb Biopharma Sprl Antibodies
BR102020009679A2 (pt) 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
TW202304890A (zh) * 2021-04-14 2023-02-01 美商百歐克斯製藥公司 Klk5雙環雜芳香族抑制劑
WO2022253911A1 (en) 2021-06-01 2022-12-08 Sixera Pharma Ab Oil-in-water emulsion of 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,l-benzoxazin-4-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB115399A (en) * 1917-03-28 1918-04-29 Reginald Guley Lewis Improved Delivery mechanism for Coin-freed Apparatus and the like.
GB1153994A (en) * 1965-07-21 1969-06-04 Aspro Nicholas Ltd Hydroxyphenyl Anthranilic Acid Derivatives Capable of Absorbing 'Ultra-Violet Light and Compositions containing them
WO1999048878A1 (en) * 1998-03-24 1999-09-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
JP5044214B2 (ja) 2003-06-06 2012-10-10 アレクシス・アクチボラゲット 皮膚状態または癌の処置のためのscce阻害剤としての縮合複素環化合物の使用
TWI419884B (zh) 2010-06-24 2013-12-21 Univ Chang Gung 苯并雜氧嗪酮衍生物,其製備方法以及包含有此等衍生物的藥學組成物
LT3097085T (lt) * 2014-01-23 2020-10-12 Sixera Pharma Ab Benzoksazinono dariniai, skirti odos ligų gydymui

Also Published As

Publication number Publication date
CN106132941A (zh) 2016-11-16
EP3097085B1 (en) 2020-07-29
CY1123477T1 (el) 2022-03-24
US9695194B2 (en) 2017-07-04
SMT202000557T1 (it) 2020-11-10
AU2015209761A1 (en) 2016-07-07
RS60830B1 (sr) 2020-10-30
CA2934025A1 (en) 2015-07-30
HRP20201500T1 (hr) 2020-12-25
JP6448651B2 (ja) 2019-01-09
US20170267692A1 (en) 2017-09-21
LT3097085T (lt) 2020-10-12
US10072024B2 (en) 2018-09-11
CN106132941B (zh) 2018-04-06
EP3097085A4 (en) 2017-08-09
SI3097085T1 (sl) 2020-11-30
EP3097085A1 (en) 2016-11-30
HUE051296T2 (hu) 2021-03-01
JP2017503798A (ja) 2017-02-02
CA2934025C (en) 2022-06-07
AU2015209761B2 (en) 2018-11-29
ES2820868T3 (es) 2021-04-22
DK3097085T3 (da) 2020-10-26
US20170002021A1 (en) 2017-01-05
PL3097085T3 (pl) 2021-01-11
WO2015112081A1 (en) 2015-07-30

Similar Documents

Publication Publication Date Title
PT3212233T (pt) Terapia combinada para o tratamento de doenças
SMT202000557T1 (it) Derivati di benzoassazinone per il trattamento di malattie della pelle
IL253244B1 (en) Methods for treating retinal diseases
LT3122878T (lt) Terapija mrnr, skirta akių ligų gydymui
PL3851537T3 (pl) Leczenie hiperbilirubinemii
HUE059303T2 (hu) Acetilkolin-észteráz-gátlók bõrbetegségek kezelésére
IL249502B (en) New therapeutic uses of benzylideneguanidine derivatives for the treatment of diseases caused by structurally abnormal proteins
SMT202100082T1 (it) Composti eteroarilici per il trattamento di malattie oftalmiche
IL246721B (en) History of 5-benzylisoquinoline for the treatment of cardiovascular diseases
PL3151814T3 (pl) Leczenie zmiany skórnej
EP3340974A4 (en) METHODS OF TREATING DISEASES
GB201412578D0 (en) Treatment of neurological diseases
ZA201807692B (en) New use of product for skin treatment
HUE070257T2 (hu) Vegyületek a lipofuscinhoz kapcsolódó betegségek kezelésére
EP3154637A4 (en) Treatment of virus-based diseases of the skin
IL259381B (en) Mirabegron for the treatment of retinal diseases
HUE062134T2 (hu) Mitokondriális betegségek kezelése
EP3271017A4 (en) Treatment of skin conditions
PT3546585T (pt) Ácidos nucleicos compreendendo um intrão modificado para utilização no tratamento de hiperbilirrubinemia
AU2015900943A0 (en) Treatment of skin conditions