SI2935269T1 - Terapevtsko aktivni pirazolo-pirimidinski derivati - Google Patents
Terapevtsko aktivni pirazolo-pirimidinski derivatiInfo
- Publication number
- SI2935269T1 SI2935269T1 SI201331080T SI201331080T SI2935269T1 SI 2935269 T1 SI2935269 T1 SI 2935269T1 SI 201331080 T SI201331080 T SI 201331080T SI 201331080 T SI201331080 T SI 201331080T SI 2935269 T1 SI2935269 T1 SI 2935269T1
- Authority
- SI
- Slovenia
- Prior art keywords
- therapeutically active
- pyrimidine derivatives
- active pyrazolo
- pyrazolo
- pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1223021.5A GB201223021D0 (en) | 2012-12-20 | 2012-12-20 | Therapeutic agents |
| GBGB1301935.1A GB201301935D0 (en) | 2013-02-04 | 2013-02-04 | Therapeutic agents |
| PCT/EP2013/077846 WO2014096423A1 (en) | 2012-12-20 | 2013-12-20 | Therapeutically active pyrazolo-pyrimidine derivatives |
| EP13814962.0A EP2935269B1 (en) | 2012-12-20 | 2013-12-20 | Therapeutically active pyrazolo-pyrimidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2935269T1 true SI2935269T1 (sl) | 2018-09-28 |
Family
ID=49886937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201331080T SI2935269T1 (sl) | 2012-12-20 | 2013-12-20 | Terapevtsko aktivni pirazolo-pirimidinski derivati |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US9714248B2 (sl) |
| EP (1) | EP2935269B1 (sl) |
| JP (1) | JP6298830B2 (sl) |
| KR (1) | KR102215490B1 (sl) |
| CN (1) | CN105008360B (sl) |
| AP (1) | AP2015008552A0 (sl) |
| AU (1) | AU2013366480B2 (sl) |
| BR (1) | BR112015014869A2 (sl) |
| CA (1) | CA2893704C (sl) |
| CL (1) | CL2015001752A1 (sl) |
| CR (1) | CR20150379A (sl) |
| CY (1) | CY1120415T1 (sl) |
| DK (1) | DK2935269T3 (sl) |
| EA (1) | EA027752B1 (sl) |
| ES (1) | ES2676515T3 (sl) |
| HK (1) | HK1215705A1 (sl) |
| HR (1) | HRP20181008T1 (sl) |
| HU (1) | HUE038310T2 (sl) |
| IL (1) | IL239163B (sl) |
| LT (1) | LT2935269T (sl) |
| MX (1) | MX2015007774A (sl) |
| MY (1) | MY189182A (sl) |
| NZ (1) | NZ709360A (sl) |
| PE (1) | PE20151767A1 (sl) |
| PH (1) | PH12015501222A1 (sl) |
| PL (1) | PL2935269T3 (sl) |
| PT (1) | PT2935269T (sl) |
| SA (1) | SA515360627B1 (sl) |
| SG (2) | SG10201703094UA (sl) |
| SI (1) | SI2935269T1 (sl) |
| TN (1) | TN2015000285A1 (sl) |
| TR (1) | TR201809140T4 (sl) |
| WO (1) | WO2014096423A1 (sl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201410815D0 (en) * | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201517263D0 (en) | 2015-09-30 | 2015-11-11 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201517264D0 (en) * | 2015-09-30 | 2015-11-11 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201521767D0 (en) * | 2015-12-10 | 2016-01-27 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven K U Leuven R&D | Therapeutic agents |
| CN110650738B (zh) | 2017-03-20 | 2023-05-09 | 博德研究所 | 用于治疗寄生虫病的化合物和方法 |
| CN109721531B (zh) * | 2017-10-27 | 2022-07-29 | 中国科学院合肥物质科学研究院 | 一种新型的脂质体激酶抑制剂 |
| UY38051A (es) | 2018-01-17 | 2019-08-30 | Glaxosmithkline Ip Dev Ltd | INHIBIDORES DE LA PI4KIIIß |
| CN112752761B (zh) | 2018-08-21 | 2024-03-29 | 杏林制药株式会社 | 双环杂芳族环衍生物 |
| EP4161518A1 (en) * | 2020-06-08 | 2023-04-12 | University of Vermont and State Agricultural College | Arylacetamide analogs of piperazine-[1,2,4]triazolo[4,3-b]pyridazines |
| CN116444485B (zh) * | 2023-03-30 | 2024-01-23 | 广西中医药大学 | 吡啶基取代不对称脲的非金属催化、免柱层析合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1110649B (de) * | 1957-11-22 | 1961-07-13 | Ciba Geigy | Verfahren zur Herstellung von 1-Isopropyl-pyrazolo[3, 4-d]pyrimidinen |
| EP1067123B1 (en) * | 1998-03-31 | 2011-01-19 | Kyowa Hakko Kirin Co., Ltd. | Nitrogenous heterocyclic compounds |
| US6815444B2 (en) * | 2002-05-24 | 2004-11-09 | National Health Research Institutes | Anti-enterovirus compounds |
| JP5335191B2 (ja) * | 2003-08-22 | 2013-11-06 | デンドレオン コーポレイション | Ｔｒｐ−ｐ８発現に関連する疾患の処置をするための組成物および方法 |
| WO2005117909A2 (en) * | 2004-04-23 | 2005-12-15 | Exelixis, Inc. | Kinase modulators and methods of use |
| US20080081817A1 (en) * | 2004-07-23 | 2008-04-03 | Tanabe Seiyaku Co., Ltd. | Nitrogenous Fused Bicyclic Compound |
| US7994172B2 (en) * | 2004-12-28 | 2011-08-09 | Exelixis, Inc. | [1H-pyrazolo[3, 4-D]pyrimidin-4-yl]-piperidine or -piperazine compounds as serine-theoronine kinase modulators (P70s6k, Atk1 and Atk2) for the treatment of immunological, inflammatory and proliferative diseases |
| EP2252616B1 (en) * | 2008-01-30 | 2014-07-23 | Genentech, Inc. | Pyrazolopyrimidine pi3k inhibitor compounds and methods of use |
| CA2754890C (en) * | 2009-03-13 | 2018-01-16 | Piet Herdewijn | Bicyclic heterocycles |
| WO2010118367A2 (en) * | 2009-04-10 | 2010-10-14 | Progenics Pharmaceuticals, Inc. | Antiviral pyrimidines |
-
2013
- 2013-12-20 TR TR2018/09140T patent/TR201809140T4/tr unknown
- 2013-12-20 KR KR1020157018482A patent/KR102215490B1/ko active IP Right Grant
- 2013-12-20 MY MYPI2015701917A patent/MY189182A/en unknown
- 2013-12-20 PE PE2015001053A patent/PE20151767A1/es unknown
- 2013-12-20 EP EP13814962.0A patent/EP2935269B1/en active Active
- 2013-12-20 CA CA2893704A patent/CA2893704C/en active Active
- 2013-12-20 AU AU2013366480A patent/AU2013366480B2/en not_active Ceased
- 2013-12-20 PT PT138149620T patent/PT2935269T/pt unknown
- 2013-12-20 HU HUE13814962A patent/HUE038310T2/hu unknown
- 2013-12-20 AP AP2015008552A patent/AP2015008552A0/xx unknown
- 2013-12-20 JP JP2015548662A patent/JP6298830B2/ja not_active Expired - Fee Related
- 2013-12-20 PL PL13814962T patent/PL2935269T3/pl unknown
- 2013-12-20 EA EA201500654A patent/EA027752B1/ru not_active IP Right Cessation
- 2013-12-20 ES ES13814962.0T patent/ES2676515T3/es active Active
- 2013-12-20 CN CN201380066813.4A patent/CN105008360B/zh not_active Expired - Fee Related
- 2013-12-20 WO PCT/EP2013/077846 patent/WO2014096423A1/en active Application Filing
- 2013-12-20 BR BR112015014869A patent/BR112015014869A2/pt not_active Application Discontinuation
- 2013-12-20 SG SG10201703094UA patent/SG10201703094UA/en unknown
- 2013-12-20 SI SI201331080T patent/SI2935269T1/sl unknown
- 2013-12-20 US US14/650,771 patent/US9714248B2/en not_active Ceased
- 2013-12-20 LT LTEP13814962.0T patent/LT2935269T/lt unknown
- 2013-12-20 MX MX2015007774A patent/MX2015007774A/es active IP Right Grant
- 2013-12-20 NZ NZ709360A patent/NZ709360A/en not_active IP Right Cessation
- 2013-12-20 DK DK13814962.0T patent/DK2935269T3/en active
- 2013-12-20 SG SG11201504291SA patent/SG11201504291SA/en unknown
-
2015
- 2015-06-01 PH PH12015501222A patent/PH12015501222A1/en unknown
- 2015-06-03 IL IL239163A patent/IL239163B/en active IP Right Grant
- 2015-06-18 SA SA515360627A patent/SA515360627B1/ar unknown
- 2015-06-18 CL CL2015001752A patent/CL2015001752A1/es unknown
- 2015-06-18 TN TNP2015000285A patent/TN2015000285A1/fr unknown
- 2015-07-17 CR CR20150379A patent/CR20150379A/es unknown
-
2016
- 2016-03-30 HK HK16103653.4A patent/HK1215705A1/zh not_active IP Right Cessation
-
2018
- 2018-06-28 HR HRP20181008TT patent/HRP20181008T1/hr unknown
- 2018-07-11 CY CY20181100728T patent/CY1120415T1/el unknown
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