SI2346845T1 - Postopek za pripravo nebivolol-a - Google Patents

Postopek za pripravo nebivolol-a

Info

Publication number
SI2346845T1
SI2346845T1 SI200931205T SI200931205T SI2346845T1 SI 2346845 T1 SI2346845 T1 SI 2346845T1 SI 200931205 T SI200931205 T SI 200931205T SI 200931205 T SI200931205 T SI 200931205T SI 2346845 T1 SI2346845 T1 SI 2346845T1
Authority
SI
Slovenia
Prior art keywords
preparing nebivolol
nebivolol
preparing
Prior art date
Application number
SI200931205T
Other languages
English (en)
Inventor
Paolo Maragni
Ivan Michieletto
Raffaella Volpicelli
Giorgio Soriato
Johnny Foletto
Livius Cotarca
Massimo Verzini
Original Assignee
Zach System S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System S.P.A. filed Critical Zach System S.P.A.
Publication of SI2346845T1 publication Critical patent/SI2346845T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
SI200931205T 2008-10-31 2009-10-28 Postopek za pripravo nebivolol-a SI2346845T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2008A001924A IT1392067B1 (it) 2008-10-31 2008-10-31 Processo di preparazione di nebivololo
PCT/EP2009/064230 WO2010049455A1 (en) 2008-10-31 2009-10-28 Process for preparing nebivolol
EP09751854.2A EP2346845B1 (en) 2008-10-31 2009-10-28 Process for preparing nebivolol

Publications (1)

Publication Number Publication Date
SI2346845T1 true SI2346845T1 (sl) 2015-10-30

Family

ID=40849284

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200931205T SI2346845T1 (sl) 2008-10-31 2009-10-28 Postopek za pripravo nebivolol-a

Country Status (17)

Country Link
US (1) US8927742B2 (sl)
EP (1) EP2346845B1 (sl)
JP (1) JP5560279B2 (sl)
CN (1) CN102186835B (sl)
AU (1) AU2009309680B2 (sl)
BR (1) BRPI0921632B8 (sl)
CA (1) CA2737340C (sl)
DK (1) DK2346845T3 (sl)
ES (1) ES2540092T3 (sl)
HR (1) HRP20150554T1 (sl)
HU (1) HUE025673T2 (sl)
IL (1) IL211497A (sl)
IT (1) IT1392067B1 (sl)
PL (1) PL2346845T3 (sl)
PT (1) PT2346845E (sl)
SI (1) SI2346845T1 (sl)
WO (1) WO2010049455A1 (sl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2907809T (pt) 2014-02-14 2019-01-16 Corden Pharma Int Gmbh Processo sem base para a preparação de intermediários de cetona utilizáveis para fabrico de nebivolol
EP2907810A1 (en) 2014-02-14 2015-08-19 Corden Pharma International GmbH A new method for producing nebivolol hydrochloride of high purity
DE102014107132A1 (de) 2014-05-20 2015-11-26 Corden Pharma International Gmbh Verfahren zur Herstellung von Epoxiden die in der Herstellung von Nebivolol und dessen Derivaten einsetzbar sind

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
HU227236B1 (en) * 2002-11-06 2010-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag New process for the production of racemic and the pure [2s[2r*[r[r*]]]]-and [2r[2s*[s[s*]]]]-enantiomers of nebivolol
RU2378272C2 (ru) * 2004-07-30 2010-01-10 Торрент Фармасьютикалз Лимитед Небиволол и его фармацевтически приемлемые соли, способ их получения и фармацевтические композиции небиволола
ES2341250T3 (es) * 2004-08-11 2010-06-17 Hetero Drugs Limited Procedimiento novedoso de preparacion de intermediarios de nebivolol.
EP1803716B1 (en) * 2005-12-28 2012-07-25 Acino Pharma AG A process for preparation of racemic nebivolol
CN101553485B (zh) * 2006-11-27 2013-02-06 Zach系统股份公司 制备奈必洛尔的方法

Also Published As

Publication number Publication date
IT1392067B1 (it) 2012-02-09
BRPI0921632B8 (pt) 2021-05-25
CN102186835B (zh) 2016-01-13
HUE025673T2 (en) 2016-04-28
DK2346845T3 (en) 2015-06-08
HRP20150554T1 (hr) 2015-07-03
JP5560279B2 (ja) 2014-07-23
BRPI0921632A8 (pt) 2017-07-11
BRPI0921632B1 (pt) 2021-03-23
WO2010049455A1 (en) 2010-05-06
ES2540092T3 (es) 2015-07-08
IL211497A0 (en) 2011-05-31
EP2346845A1 (en) 2011-07-27
IL211497A (en) 2014-12-31
BRPI0921632A2 (pt) 2015-08-18
CA2737340C (en) 2016-09-06
CN102186835A (zh) 2011-09-14
AU2009309680A1 (en) 2010-05-06
CA2737340A1 (en) 2010-05-06
ITMI20081924A1 (it) 2010-05-01
US20110207948A1 (en) 2011-08-25
US8927742B2 (en) 2015-01-06
EP2346845B1 (en) 2015-03-25
AU2009309680B2 (en) 2015-08-06
PL2346845T3 (pl) 2015-08-31
PT2346845E (pt) 2015-07-30
JP2012506894A (ja) 2012-03-22

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