SI2155677T1 - Mono-hidrokloridne soli inhibitorja histonske deacetilaze - Google Patents

Mono-hidrokloridne soli inhibitorja histonske deacetilaze

Info

Publication number
SI2155677T1
SI2155677T1 SI200831339T SI200831339T SI2155677T1 SI 2155677 T1 SI2155677 T1 SI 2155677T1 SI 200831339 T SI200831339 T SI 200831339T SI 200831339 T SI200831339 T SI 200831339T SI 2155677 T1 SI2155677 T1 SI 2155677T1
Authority
SI
Slovenia
Prior art keywords
mono
inhibitor
histone deacetylase
hydrochloric salts
hydrochloric
Prior art date
Application number
SI200831339T
Other languages
English (en)
Inventor
Julius W.J. Dickens
Ioannes Nicolaos Houpis
Yolande Lydia Lang
Carina Leys
Sigrid Carl Maria Stokbroekx
Johan Erwin Edmond Weerts
Original Assignee
Janssen Pharmaceutica, N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38659779&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2155677(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica, N.V. filed Critical Janssen Pharmaceutica, N.V.
Publication of SI2155677T1 publication Critical patent/SI2155677T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
SI200831339T 2007-05-14 2008-05-13 Mono-hidrokloridne soli inhibitorja histonske deacetilaze SI2155677T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91782107P 2007-05-14 2007-05-14
EP07108176 2007-05-14
EP08750252.2A EP2155677B1 (en) 2007-05-14 2008-05-13 Mono-hydrochloric salts of an inhibitor of histone deacetylase
PCT/EP2008/055804 WO2008138918A1 (en) 2007-05-14 2008-05-13 Mono-hydrochloric salts of an inhibitor of histone deacetylase

Publications (1)

Publication Number Publication Date
SI2155677T1 true SI2155677T1 (sl) 2015-01-30

Family

ID=38659779

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831339T SI2155677T1 (sl) 2007-05-14 2008-05-13 Mono-hidrokloridne soli inhibitorja histonske deacetilaze

Country Status (33)

Country Link
US (2) US20100130523A1 (sl)
EP (1) EP2155677B1 (sl)
JP (1) JP2010526851A (sl)
KR (1) KR101540679B1 (sl)
CN (1) CN101679256B (sl)
AP (1) AP2717A (sl)
AR (2) AR066550A1 (sl)
AU (1) AU2008250047B2 (sl)
BR (1) BRPI0811859B8 (sl)
CA (1) CA2683195C (sl)
CL (1) CL2008001390A1 (sl)
CO (1) CO6140031A2 (sl)
CR (1) CR11163A (sl)
CY (1) CY1115837T1 (sl)
DK (1) DK2155677T3 (sl)
EA (1) EA018326B1 (sl)
EC (1) ECSP099729A (sl)
ES (1) ES2525456T3 (sl)
HK (1) HK1140479A1 (sl)
HR (1) HRP20141180T1 (sl)
IL (1) IL202042A0 (sl)
JO (1) JO2959B1 (sl)
MX (1) MX2009012332A (sl)
NZ (1) NZ599674A (sl)
PA (1) PA8780301A1 (sl)
PL (1) PL2155677T3 (sl)
PT (1) PT2155677E (sl)
RS (1) RS53672B1 (sl)
SG (1) SG182986A1 (sl)
SI (1) SI2155677T1 (sl)
TW (1) TWI414294B (sl)
UA (1) UA100510C2 (sl)
WO (1) WO2008138918A1 (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009015917A2 (en) 2007-05-14 2009-02-05 F. Hoffmann-La Roche Ag Dihydroquinone and dihydronaphthridine inhibitors of jnk

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924990B2 (ja) * 1979-11-21 1984-06-13 協和醗酵工業株式会社 新規なピペリジン誘導体
HU221227B1 (en) 1995-12-08 2002-08-28 Janssen Pharmaceutica Nv Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives, their preparation, pharmaceutical compositions containing them and their use
RS50980B (sr) * 2004-07-26 2010-10-31 Merck Serono Sa. Derivati n-hidroksiamida i njihova upotreba
SG156687A1 (en) * 2004-07-28 2009-11-26 Janssen Pharmaceutica Nv Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

Also Published As

Publication number Publication date
PT2155677E (pt) 2014-12-23
EA018326B1 (ru) 2013-07-30
TW200914024A (en) 2009-04-01
CR11163A (es) 2010-05-27
JP2010526851A (ja) 2010-08-05
US8759519B2 (en) 2014-06-24
EP2155677A1 (en) 2010-02-24
NZ599674A (en) 2013-02-22
ES2525456T3 (es) 2014-12-23
HK1140479A1 (en) 2010-10-15
CN101679256A (zh) 2010-03-24
AU2008250047B2 (en) 2013-01-17
CN101679256B (zh) 2013-06-26
CA2683195C (en) 2016-08-09
MX2009012332A (es) 2009-12-01
AR066550A1 (es) 2009-08-26
ECSP099729A (es) 2009-12-28
CO6140031A2 (es) 2010-03-19
AP2717A (en) 2013-07-31
AP2009005039A0 (en) 2009-12-31
AU2008250047A1 (en) 2008-11-20
US20100130523A1 (en) 2010-05-27
EA200971031A1 (ru) 2010-04-30
PA8780301A1 (es) 2008-12-18
TWI414294B (zh) 2013-11-11
SG182986A1 (en) 2012-08-30
IL202042A0 (en) 2010-06-16
KR101540679B1 (ko) 2015-07-30
AR118361A2 (es) 2021-09-29
CA2683195A1 (en) 2008-11-20
EP2155677B1 (en) 2014-10-01
UA100510C2 (ru) 2013-01-10
KR20100015647A (ko) 2010-02-12
JO2959B1 (en) 2016-03-15
US20120289527A1 (en) 2012-11-15
CY1115837T1 (el) 2017-01-25
WO2008138918A1 (en) 2008-11-20
BRPI0811859A2 (pt) 2014-11-18
RS53672B1 (en) 2015-04-30
BRPI0811859B1 (pt) 2020-02-11
DK2155677T3 (en) 2015-01-05
CL2008001390A1 (es) 2008-11-21
PL2155677T3 (pl) 2015-03-31
HRP20141180T1 (hr) 2015-02-13
BRPI0811859B8 (pt) 2021-05-25

Similar Documents

Publication Publication Date Title
HK1220179A1 (zh) 組蛋白去乙酰的抑制劑
EP2217588A4 (en) INHIBITORS OF HISTONE DEACETYLASE
ZA200906609B (en) Inhibitors of histone deacetylase
HK1142597A1 (en) Inhibitors of histone deacetylase
EP1991226A4 (en) Histone deacetylase INHIBITORS
HK1128285A1 (en) Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
IL205241A0 (en) Histone deacetylase inhibitors
EP2170076A4 (en) 4-CARBOXYBENZYLAMINO DERIVATIVES AS HISTONDEACETYLASE INHIBITORS
EP2265590A4 (en) SELECTIVE INHIBITORS OF HISTONE DEACETYLASE
HK1126769A1 (en) Benzamide derivatives as inhibitors of histone deacetylase
IL193458A0 (en) Histone deacetylase inhibitors
EP2049124A4 (en) PHOSPHOR DERIVATIVES AS HISTONDEACETYLASE HEMMER
EP1991247A4 (en) BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS
AU2008300827A8 (en) Novel tetrahydrofusedpyridines as histone deacetylase inhibitors
EP1973872A4 (en) HISTONDEACETYLASE HEMMER AND PROPHARMAKA THEREOF
IL198263A0 (en) Hydroxamates as inhibitors of histone deacetylase
EP2451790A4 (en) INHIBITORS OF HISTONE DEACETYLASE
ZA200800901B (en) Histone deacetylase inhibitors
EP2045239A4 (en) Novel derivatives of phthalimide as histone deacetylase inhibitors
EP2308868A4 (en) HISTONDEACETYLASEINHIBITORS AND APPLICATIONS THEREOF
EP2205070A4 (en) N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE
EP2231596A4 (en) INHIBITORS OF HISTONATE ACETYLASE
EP2205563A4 (en) NEW HISTONDEACETYLASE INHIBITORS
ZA201001972B (en) Novel teteahydrofusedpyridines as histone deacetylase inhibitors
IL202042A0 (en) Mono-hydrochloric salts of an inhibitor of histone deacetylase