SI2125714T1 - Hidrokloridna sol 5-(3-(3-hidroksifenoksi)azetidin-1-il)-5-metil-2,2-difenilheksanamida - Google Patents

Hidrokloridna sol 5-(3-(3-hidroksifenoksi)azetidin-1-il)-5-metil-2,2-difenilheksanamida

Info

Publication number
SI2125714T1
SI2125714T1 SI200830366T SI200830366T SI2125714T1 SI 2125714 T1 SI2125714 T1 SI 2125714T1 SI 200830366 T SI200830366 T SI 200830366T SI 200830366 T SI200830366 T SI 200830366T SI 2125714 T1 SI2125714 T1 SI 2125714T1
Authority
SI
Slovenia
Prior art keywords
diphenylhexanamide
hydroxyphenoxy
azetidin
methyl
hydrochloride salt
Prior art date
Application number
SI200830366T
Other languages
English (en)
Inventor
Paul Alan Glossop
Kim James
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39591485&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2125714(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of SI2125714T1 publication Critical patent/SI2125714T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200830366T 2007-03-16 2008-03-06 Hidrokloridna sol 5-(3-(3-hidroksifenoksi)azetidin-1-il)-5-metil-2,2-difenilheksanamida SI2125714T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89516307P 2007-03-16 2007-03-16
PCT/IB2008/000622 WO2008135819A1 (en) 2007-03-16 2008-03-06 Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide
EP08719316A EP2125714B1 (en) 2007-03-16 2008-03-06 Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide

Publications (1)

Publication Number Publication Date
SI2125714T1 true SI2125714T1 (sl) 2011-10-28

Family

ID=39591485

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830366T SI2125714T1 (sl) 2007-03-16 2008-03-06 Hidrokloridna sol 5-(3-(3-hidroksifenoksi)azetidin-1-il)-5-metil-2,2-difenilheksanamida

Country Status (24)

Country Link
US (1) US8263583B2 (sl)
EP (1) EP2125714B1 (sl)
JP (1) JP4277051B2 (sl)
KR (1) KR101120227B1 (sl)
CN (2) CN101641327A (sl)
AR (1) AR065714A1 (sl)
AT (1) ATE512132T1 (sl)
AU (1) AU2008247095B2 (sl)
BR (1) BRPI0808413A2 (sl)
CA (1) CA2678683C (sl)
CY (1) CY1111701T1 (sl)
DK (1) DK2125714T3 (sl)
ES (1) ES2364727T3 (sl)
HK (1) HK1189591A1 (sl)
IL (1) IL200403A (sl)
MX (1) MX2009009952A (sl)
NZ (1) NZ579056A (sl)
PL (1) PL2125714T3 (sl)
PT (1) PT2125714E (sl)
RU (1) RU2422439C2 (sl)
SI (1) SI2125714T1 (sl)
TW (1) TWI348907B (sl)
WO (1) WO2008135819A1 (sl)
ZA (1) ZA200906462B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ599774A (en) 2009-11-23 2014-11-28 Palatin Technologies Inc Melanocortin-1 receptor-specific cyclic peptides
EA201290295A1 (ru) 2009-11-23 2013-01-30 Палатин Текнолоджиз, Инк. Специфичные к рецептору меланокортина-1 линейные пептиды
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP3596046A1 (en) * 2017-03-15 2020-01-22 Mylan Laboratories Ltd. Novel polymorphs of (5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide hydrochloride
CA3128468A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2020261160A1 (en) * 2019-06-25 2020-12-30 Mylan Laboratories Limited Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
CN116033893A (zh) * 2020-06-26 2023-04-28 迈兰制药英国有限公司 包含5-[3-(3-羟基苯氧基)氮杂环丁烷-1-基]-5-甲基-2,2-二苯基己酰胺的制剂
CN113577059B (zh) * 2021-08-02 2022-05-20 山东大学齐鲁医院(青岛) 一种用于小儿哮喘的活性药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69720518T2 (de) * 1996-12-02 2004-02-26 Kyorin Pharmaceutical Co., Ltd. Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren
JPH11100366A (ja) 1997-09-29 1999-04-13 Kyorin Pharmaceut Co Ltd 新規n−置換環状アミン誘導体及びその製造法
EP1928821B1 (en) * 2005-09-21 2009-01-07 Pfizer Limited Carboxamide derivatives as muscarinic receptor antagonists
WO2008035157A1 (en) * 2006-09-22 2008-03-27 Pfizer Limited Azetidine derivatives as muscarinic receptor antagonists

Also Published As

Publication number Publication date
WO2008135819A8 (en) 2009-08-27
TWI348907B (en) 2011-09-21
IL200403A0 (en) 2010-04-29
PL2125714T3 (pl) 2011-10-31
RU2009134512A (ru) 2011-03-20
AR065714A1 (es) 2009-06-24
CN103351367B (zh) 2015-06-10
US20100113409A1 (en) 2010-05-06
WO2008135819A1 (en) 2008-11-13
ZA200906462B (en) 2010-06-30
EP2125714A1 (en) 2009-12-02
RU2422439C2 (ru) 2011-06-27
US8263583B2 (en) 2012-09-11
IL200403A (en) 2014-08-31
EP2125714B1 (en) 2011-06-08
ES2364727T3 (es) 2011-09-13
HK1189591A1 (en) 2014-06-13
CA2678683A1 (en) 2008-11-13
CY1111701T1 (el) 2015-10-07
CN101641327A (zh) 2010-02-03
NZ579056A (en) 2011-07-29
DK2125714T3 (da) 2011-07-25
AU2008247095B2 (en) 2012-12-13
KR101120227B1 (ko) 2012-03-20
AU2008247095A1 (en) 2008-11-13
MX2009009952A (es) 2009-10-08
JP2009001543A (ja) 2009-01-08
CN103351367A (zh) 2013-10-16
KR20090110944A (ko) 2009-10-23
PT2125714E (pt) 2011-07-14
CA2678683C (en) 2012-05-15
ATE512132T1 (de) 2011-06-15
TW200904408A (en) 2009-02-01
BRPI0808413A2 (pt) 2014-07-15
JP4277051B2 (ja) 2009-06-10

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