ZA200906462B - Hydrochloride salt of 5-[-3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2, 2-diphenylhexanamide - Google Patents

Hydrochloride salt of 5-[-3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2, 2-diphenylhexanamide

Info

Publication number
ZA200906462B
ZA200906462B ZA200906462A ZA200906462A ZA200906462B ZA 200906462 B ZA200906462 B ZA 200906462B ZA 200906462 A ZA200906462 A ZA 200906462A ZA 200906462 A ZA200906462 A ZA 200906462A ZA 200906462 B ZA200906462 B ZA 200906462B
Authority
ZA
South Africa
Prior art keywords
diphenylhexanamide
hydroxyphenoxy
azetidin
methyl
hydrochloride salt
Prior art date
Application number
ZA200906462A
Other languages
English (en)
Inventor
Paul Alan Glossop
Kim James
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39591485&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200906462(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of ZA200906462B publication Critical patent/ZA200906462B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200906462A 2007-03-16 2009-09-16 Hydrochloride salt of 5-[-3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2, 2-diphenylhexanamide ZA200906462B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89516307P 2007-03-16 2007-03-16

Publications (1)

Publication Number Publication Date
ZA200906462B true ZA200906462B (en) 2010-06-30

Family

ID=39591485

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200906462A ZA200906462B (en) 2007-03-16 2009-09-16 Hydrochloride salt of 5-[-3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2, 2-diphenylhexanamide

Country Status (24)

Country Link
US (1) US8263583B2 (xx)
EP (1) EP2125714B1 (xx)
JP (1) JP4277051B2 (xx)
KR (1) KR101120227B1 (xx)
CN (2) CN101641327A (xx)
AR (1) AR065714A1 (xx)
AT (1) ATE512132T1 (xx)
AU (1) AU2008247095B2 (xx)
BR (1) BRPI0808413A2 (xx)
CA (1) CA2678683C (xx)
CY (1) CY1111701T1 (xx)
DK (1) DK2125714T3 (xx)
ES (1) ES2364727T3 (xx)
HK (1) HK1189591A1 (xx)
IL (1) IL200403A (xx)
MX (1) MX2009009952A (xx)
NZ (1) NZ579056A (xx)
PL (1) PL2125714T3 (xx)
PT (1) PT2125714E (xx)
RU (1) RU2422439C2 (xx)
SI (1) SI2125714T1 (xx)
TW (1) TWI348907B (xx)
WO (1) WO2008135819A1 (xx)
ZA (1) ZA200906462B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102712674A (zh) 2009-11-23 2012-10-03 帕拉丁科技公司 黑皮质素-1受体-特异性的线性肽
EA021897B1 (ru) 2009-11-23 2015-09-30 Палатин Текнолоджиз, Инк. Циклические пептиды, специфичные к рецептору меланокортина-1
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP3596046A1 (en) 2017-03-15 2020-01-22 Mylan Laboratories Ltd. Novel polymorphs of (5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide hydrochloride
CN114732910A (zh) 2017-10-05 2022-07-12 弗尔康医疗公司 P38激酶抑制剂降低dux4和下游基因表达以用于治疗fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2020261160A1 (en) * 2019-06-25 2020-12-30 Mylan Laboratories Limited Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
WO2021260441A1 (en) * 2020-06-26 2021-12-30 Mylan Pharma Uk Limited Formulations including 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
CN113577059B (zh) * 2021-08-02 2022-05-20 山东大学齐鲁医院(青岛) 一种用于小儿哮喘的活性药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69720518T2 (de) * 1996-12-02 2004-02-26 Kyorin Pharmaceutical Co., Ltd. Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren
JPH11100366A (ja) 1997-09-29 1999-04-13 Kyorin Pharmaceut Co Ltd 新規ｎ−置換環状アミン誘導体及びその製造法
CN101268046B (zh) * 2005-09-21 2012-07-25 辉瑞有限公司 作为毒蕈碱性受体拮抗剂的碳酰胺衍生物
US20100160279A1 (en) * 2006-09-22 2010-06-24 Pfizer Inc Azetidine Derivatives as Muscarinic Receptor Antagonists

Also Published As

Publication number Publication date
AU2008247095A1 (en) 2008-11-13
RU2422439C2 (ru) 2011-06-27
KR101120227B1 (ko) 2012-03-20
BRPI0808413A2 (pt) 2014-07-15
KR20090110944A (ko) 2009-10-23
US8263583B2 (en) 2012-09-11
MX2009009952A (es) 2009-10-08
AR065714A1 (es) 2009-06-24
IL200403A0 (en) 2010-04-29
PL2125714T3 (pl) 2011-10-31
WO2008135819A1 (en) 2008-11-13
EP2125714B1 (en) 2011-06-08
ES2364727T3 (es) 2011-09-13
PT2125714E (pt) 2011-07-14
TWI348907B (en) 2011-09-21
JP2009001543A (ja) 2009-01-08
TW200904408A (en) 2009-02-01
RU2009134512A (ru) 2011-03-20
IL200403A (en) 2014-08-31
CN103351367B (zh) 2015-06-10
CN101641327A (zh) 2010-02-03
EP2125714A1 (en) 2009-12-02
CA2678683A1 (en) 2008-11-13
JP4277051B2 (ja) 2009-06-10
CY1111701T1 (el) 2015-10-07
AU2008247095B2 (en) 2012-12-13
NZ579056A (en) 2011-07-29
CA2678683C (en) 2012-05-15
WO2008135819A8 (en) 2009-08-27
CN103351367A (zh) 2013-10-16
ATE512132T1 (de) 2011-06-15
US20100113409A1 (en) 2010-05-06
HK1189591A1 (en) 2014-06-13
DK2125714T3 (da) 2011-07-25
SI2125714T1 (sl) 2011-10-28

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