SI2018388T1 - Bisadenozinske spojine kot agonisti adenozinskega A2A receptorja - Google Patents

Bisadenozinske spojine kot agonisti adenozinskega A2A receptorja

Info

Publication number
SI2018388T1
SI2018388T1 SI200730609T SI200730609T SI2018388T1 SI 2018388 T1 SI2018388 T1 SI 2018388T1 SI 200730609 T SI200730609 T SI 200730609T SI 200730609 T SI200730609 T SI 200730609T SI 2018388 T1 SI2018388 T1 SI 2018388T1
Authority
SI
Slovenia
Prior art keywords
bisadenosine
adenosine
compounds
receptor agonists
agonists
Prior art date
Application number
SI200730609T
Other languages
English (en)
Inventor
Robin Alec Fairhurst
Roger John Taylor
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI2018388T1 publication Critical patent/SI2018388T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI200730609T 2006-04-21 2007-04-19 Bisadenozinske spojine kot agonisti adenozinskega A2A receptorja SI2018388T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0607950.3A GB0607950D0 (en) 2006-04-21 2006-04-21 Organic compounds
EP07724376A EP2018388B9 (en) 2006-04-21 2007-04-19 Bisadenosine compounds as adenosine a2a receptor agonists
PCT/EP2007/003439 WO2007121924A2 (en) 2006-04-21 2007-04-19 Bisadenosine compounds as adenosine a2a receptor agonists

Publications (1)

Publication Number Publication Date
SI2018388T1 true SI2018388T1 (sl) 2011-07-29

Family

ID=36581047

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200730609T SI2018388T1 (sl) 2006-04-21 2007-04-19 Bisadenozinske spojine kot agonisti adenozinskega A2A receptorja

Country Status (32)

Country Link
US (1) US8193164B2 (sl)
EP (1) EP2018388B9 (sl)
JP (1) JP2009534341A (sl)
KR (1) KR20080112399A (sl)
CN (1) CN101437829B (sl)
AR (1) AR060606A1 (sl)
AT (1) ATE502040T1 (sl)
AU (1) AU2007241347A1 (sl)
CA (1) CA2648037A1 (sl)
CL (1) CL2007001132A1 (sl)
CR (1) CR10328A (sl)
CY (1) CY1111568T1 (sl)
DE (1) DE602007013203D1 (sl)
DK (1) DK2018388T3 (sl)
EC (1) ECSP088837A (sl)
ES (1) ES2363255T3 (sl)
GB (1) GB0607950D0 (sl)
GT (1) GT200800218A (sl)
HR (1) HRP20110445T1 (sl)
IL (1) IL194398A0 (sl)
MA (1) MA30404B1 (sl)
MX (1) MX2008013398A (sl)
NO (1) NO20084456L (sl)
PE (1) PE20071228A1 (sl)
PL (1) PL2018388T3 (sl)
PT (1) PT2018388E (sl)
RU (1) RU2008145715A (sl)
SI (1) SI2018388T1 (sl)
TN (1) TNSN08409A1 (sl)
TW (1) TW200813074A (sl)
WO (1) WO2007121924A2 (sl)
ZA (1) ZA200808103B (sl)

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EP2018388B9 (en) 2011-10-05
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