SI1915349T1 - Postopek za pripravo čistega amorfnega rosuvastatin kalcija - Google Patents

Postopek za pripravo čistega amorfnega rosuvastatin kalcija

Info

Publication number
SI1915349T1
SI1915349T1 SI200632034A SI200632034A SI1915349T1 SI 1915349 T1 SI1915349 T1 SI 1915349T1 SI 200632034 A SI200632034 A SI 200632034A SI 200632034 A SI200632034 A SI 200632034A SI 1915349 T1 SI1915349 T1 SI 1915349T1
Authority
SI
Slovenia
Prior art keywords
rosuvastatin calcium
pure amorphous
preparing pure
amorphous rosuvastatin
preparing
Prior art date
Application number
SI200632034A
Other languages
English (en)
Inventor
Zdenko Casar
Marko Zlicar
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37440674&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1915349(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of SI1915349T1 publication Critical patent/SI1915349T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SI200632034A 2005-06-24 2006-06-22 Postopek za pripravo čistega amorfnega rosuvastatin kalcija SI1915349T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI200500187 2005-06-24
EP06754502.0A EP1915349B2 (en) 2005-06-24 2006-06-22 Process for preparing pure amorphous rosuvastatin calcium
PCT/EP2006/006008 WO2006136408A2 (en) 2005-06-24 2006-06-22 Process for preparing pure amorphous rosuvastatin calcium

Publications (1)

Publication Number Publication Date
SI1915349T1 true SI1915349T1 (sl) 2016-05-31

Family

ID=37440674

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200632034A SI1915349T1 (sl) 2005-06-24 2006-06-22 Postopek za pripravo čistega amorfnega rosuvastatin kalcija

Country Status (12)

Country Link
US (1) US8207333B2 (sl)
EP (1) EP1915349B2 (sl)
JP (1) JP5416403B2 (sl)
CN (1) CN101203496B (sl)
AU (1) AU2006261088B2 (sl)
CA (1) CA2611920C (sl)
ES (1) ES2564807T5 (sl)
HU (1) HUE027012T2 (sl)
IL (1) IL187578A0 (sl)
PL (1) PL1915349T5 (sl)
SI (1) SI1915349T1 (sl)
WO (1) WO2006136408A2 (sl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1562912A2 (en) 2003-08-28 2005-08-17 Teva Pharmaceutical Industries Limited Process for preparation of rosuvastatin calcium
CA2546701C (en) 2003-11-24 2010-07-27 Teva Pharmaceutical Industries Ltd. Crystalline ammonium salts of rosuvastatin
ATE507209T1 (de) 2003-12-02 2011-05-15 Teva Pharma Referenzstandard zur charakterisierung von rosuvastatin
EP1737829A2 (en) 2005-02-22 2007-01-03 Teva Pharmaceutical Industries Ltd Preparation of rosuvastatin
JP5146965B2 (ja) * 2005-06-24 2013-02-20 レツク・フアーマシユーテイカルズ・デー・デー 不純物を含まない非晶質ロスバスタチンカルシウムの調製方法
JP2008515931A (ja) 2005-08-16 2008-05-15 テバ ファーマシューティカル インダストリーズ リミティド 結晶形ロスバスタチン中間体
EP1948618A1 (en) * 2006-09-18 2008-07-30 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin calcium
US8318933B2 (en) * 2006-10-31 2012-11-27 Aurobindo Pharma Ltd Process for preparing rosuvastatin calcium
ATE553098T1 (de) * 2007-02-08 2012-04-15 Aurobindo Pharma Ltd Verfahren zur herstellung von rosuvastatin- calcium
US7884226B2 (en) 2007-07-12 2011-02-08 Teva Pharmaceutical Industries, Ltd. Purification of rosuvatatin intermediate by thin film evaporation and chemical method
US8653265B2 (en) 2008-05-27 2014-02-18 Changzhou Pharmaceutical Factory Preparation method of rosuvastatin calcium and its intermediates
WO2010035284A2 (en) * 2008-09-26 2010-04-01 Matrix Laboratories Ltd An improved process for the preparation of rosuvastatin calcium
EA019995B1 (ru) * 2009-01-14 2014-07-30 Крка, Товарна Здравил, Д.Д., Ново Место Соль розувастатина, способ ее получения и способ получения фармацевтически приемлемой соли розувастатина
MX2011007478A (es) * 2009-01-15 2011-09-15 Sag Egis Gyogyszergyar Nylvanosan Muekoedoe Reszvenytarsa Proceso para la preparacion de sales de rosuvastatina.
WO2011021058A1 (en) 2009-08-17 2011-02-24 Aurobindo Pharma Limited Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester
HU230987B1 (hu) 2010-11-29 2019-08-28 Egis Gyógyszergyár Nyrt. Eljárás nagy tisztaságú gyógyszeripari intermedierek előállítására
FR2970178B1 (fr) * 2011-01-07 2014-06-20 Liliane Therese Jacquot Promedicaments pour une delivrance specifique au niveau du foie et une meilleure tolerance
CN102070537B (zh) * 2011-01-28 2012-01-11 海南美大制药有限公司 一种瑞舒伐他汀钙化合物及其新制法
WO2013046222A2 (en) * 2011-08-10 2013-04-04 Glenmark Generics Limited A process for the preparation of amorphous rosuvastatin calcium
CN103709107B (zh) * 2012-09-29 2016-04-20 安徽省庆云医药化工有限公司 瑞舒伐他汀甲酯的新晶型及其制备方法
CN104370827B (zh) * 2013-08-13 2016-09-07 天津汉瑞药业有限公司 瑞舒伐他汀钙化合物
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
US11970482B2 (en) * 2018-01-09 2024-04-30 Ligand Pharmaceuticals Inc. Acetal compounds and therapeutic uses thereof
CN108398501A (zh) * 2018-03-02 2018-08-14 海南通用三洋药业有限公司 一种检测瑞舒伐他汀钙有关物质的方法
CN108675931A (zh) * 2018-05-18 2018-10-19 合肥合源药业有限公司 一种低钡他汀钙及其制备方法
CN111170950A (zh) * 2020-01-16 2020-05-19 河南豫辰药业股份有限公司 一种瑞舒伐他汀钙盐的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0003305D0 (en) * 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
EP1562912A2 (en) * 2003-08-28 2005-08-17 Teva Pharmaceutical Industries Limited Process for preparation of rosuvastatin calcium
EP1678148A1 (en) * 2003-10-22 2006-07-12 Ranbaxy Laboratories Limited Process for the preparation of amorphous rosuvastatin calcium
WO2005054207A1 (en) 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
WO2005077917A1 (en) * 2004-01-19 2005-08-25 Ranbaxy Laboratories Limited Amorphous salts of rosuvastatin
EP1797046A2 (en) 2004-09-27 2007-06-20 Ranbaxy Laboratories Limited Novel processes for preparing amorphous rosuvastatin calcium and a novel polymorphic form of rosuvastatin sodium

Also Published As

Publication number Publication date
HUE027012T2 (en) 2016-10-28
ES2564807T5 (es) 2019-02-26
WO2006136408A3 (en) 2007-04-19
AU2006261088A1 (en) 2006-12-28
EP1915349A2 (en) 2008-04-30
EP1915349B1 (en) 2015-12-09
US20080188504A1 (en) 2008-08-07
IL187578A0 (en) 2008-03-20
CA2611920A1 (en) 2006-12-28
PL1915349T3 (pl) 2016-05-31
CN101203496B (zh) 2011-04-20
WO2006136408A2 (en) 2006-12-28
PL1915349T5 (pl) 2019-02-28
CN101203496A (zh) 2008-06-18
CA2611920C (en) 2015-05-05
US8207333B2 (en) 2012-06-26
ES2564807T3 (es) 2016-03-29
JP2008543899A (ja) 2008-12-04
AU2006261088B2 (en) 2012-11-08
EP1915349B2 (en) 2018-09-12
JP5416403B2 (ja) 2014-02-12

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