SI1805307T1 - Zaščita biološko aktivnih molekul z uporabo amfifilov - Google Patents

Zaščita biološko aktivnih molekul z uporabo amfifilov

Info

Publication number
SI1805307T1
SI1805307T1 SI200530618T SI200530618T SI1805307T1 SI 1805307 T1 SI1805307 T1 SI 1805307T1 SI 200530618 T SI200530618 T SI 200530618T SI 200530618 T SI200530618 T SI 200530618T SI 1805307 T1 SI1805307 T1 SI 1805307T1
Authority
SI
Slovenia
Prior art keywords
molecule
amphiphiles
protection
biologically active
active molecules
Prior art date
Application number
SI200530618T
Other languages
English (en)
Inventor
Marcel Herman Josef Ruiters
Original Assignee
Synvolux Ip Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL1027311A external-priority patent/NL1027311C2/nl
Priority claimed from NL1027417A external-priority patent/NL1027417C2/nl
Application filed by Synvolux Ip Bv filed Critical Synvolux Ip Bv
Publication of SI1805307T1 publication Critical patent/SI1805307T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/50Methods for regulating/modulating their activity
    • C12N2320/51Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SI200530618T 2004-10-21 2005-10-20 Zaščita biološko aktivnih molekul z uporabo amfifilov SI1805307T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL1027311A NL1027311C2 (nl) 2004-10-21 2004-10-21 Vehikel voor transport van een DNA-modificerend enzym naar een genoom.
NL1027417A NL1027417C2 (nl) 2004-10-21 2004-11-04 Vehikel voor transport van een gekozen molecuul naar een cel.
NL1027479A NL1027479C2 (nl) 2004-10-21 2004-11-10 Bescherming van biologisch actieve moleculen met behulp van amphifielen.
EP05795379A EP1805307B1 (en) 2004-10-21 2005-10-20 Protection of biologically active molecules using amphiphiles

Publications (1)

Publication Number Publication Date
SI1805307T1 true SI1805307T1 (sl) 2009-06-30

Family

ID=35583431

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200530618T SI1805307T1 (sl) 2004-10-21 2005-10-20 Zaščita biološko aktivnih molekul z uporabo amfifilov
SI200530617T SI1805306T1 (sl) 2004-10-21 2005-10-20 Vehikel za transport DNA-modificirajočega encima h genomu
SI200530616T SI1805305T1 (sl) 2004-10-21 2005-10-20 Vehikel za transport izbrane molekule k celici

Family Applications After (2)

Application Number Title Priority Date Filing Date
SI200530617T SI1805306T1 (sl) 2004-10-21 2005-10-20 Vehikel za transport DNA-modificirajočega encima h genomu
SI200530616T SI1805305T1 (sl) 2004-10-21 2005-10-20 Vehikel za transport izbrane molekule k celici

Country Status (16)

Country Link
US (4) US20070224589A1 (sl)
EP (3) EP1805306B1 (sl)
JP (2) JP2008517904A (sl)
KR (1) KR20070073796A (sl)
AT (3) ATE420954T1 (sl)
AU (1) AU2005296360B2 (sl)
CA (2) CA2583860A1 (sl)
DE (3) DE602005012420D1 (sl)
DK (3) DK1805305T3 (sl)
ES (3) ES2318550T3 (sl)
NL (1) NL1027479C2 (sl)
NO (3) NO20071599L (sl)
PL (3) PL1805305T3 (sl)
PT (3) PT1805307E (sl)
SI (3) SI1805307T1 (sl)
WO (3) WO2006043811A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009031896A2 (en) * 2007-09-07 2009-03-12 Synvolux Ip B.V. Improved liposomes and uses thereof
DE102008032594A1 (de) 2008-07-11 2010-01-14 Qiagen Gmbh Transfektionslösung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077211A (en) * 1988-07-06 1991-12-31 Applied Genetics, Inc. Purification and administration of dna repair enzymes
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
KR100252547B1 (ko) * 1991-09-05 2000-09-01 프레드 마리얀스키 폴리-또는 올리고누클레오티드의 세포로의 표적화된 전달
DE69536153D1 (de) * 1994-11-17 2011-05-05 Ich Productions Ltd Internalisierung von dna, unter verwendung von konjugaten des poly-l-lysins und eines peptidligands des integrin-rezeptors
US6726894B1 (en) * 1995-07-25 2004-04-27 Synvolux Ip B.V. Transport vehicles for macromolecules
NL1000884C2 (nl) * 1995-07-25 1997-01-28 Univ Groningen Transportvehikels voor macromoleculen.
US5958894A (en) * 1997-04-04 1999-09-28 Megabios Corporation Amphiphilic biguanide derivatives
AU2002314861A1 (en) * 2001-05-30 2002-12-09 Targesome, Inc. Targeted multivalent macromolecules
GB0117964D0 (en) * 2001-07-24 2001-09-19 Imp College Innovations Ltd Control of gene expression
CA2455598A1 (en) * 2001-07-27 2003-02-13 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
GB0124391D0 (en) * 2001-10-11 2001-11-28 Gene Expression Technologies L Control of gene expression
WO2003093449A2 (en) * 2002-05-06 2003-11-13 Nucleonics, Inc. Methods for delivery of nucleic acids
JP2006509010A (ja) * 2002-12-05 2006-03-16 インペリアル・カレッジ・イノベイションズ・リミテッド アポトーシスの制御
WO2004083432A1 (en) * 2003-03-21 2004-09-30 Academisch Ziekenhuis Leiden Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
ITMI20030821A1 (it) * 2003-04-18 2004-10-19 Internat Ct For Genetic En Gineering And Polipeptidi chimerici e loro uso.

Also Published As

Publication number Publication date
NO20071599L (no) 2007-06-26
PT1805305E (pt) 2009-04-13
PT1805307E (pt) 2009-04-13
EP1805306B1 (en) 2009-01-07
KR20070073796A (ko) 2007-07-10
CA2584633A1 (en) 2006-04-27
US20070224589A1 (en) 2007-09-27
CA2583860A1 (en) 2006-04-27
US20080085273A1 (en) 2008-04-10
US20070225230A1 (en) 2007-09-27
PT1805306E (pt) 2009-04-13
ATE420954T1 (de) 2009-01-15
NL1027479C2 (nl) 2006-05-01
AU2005296360A1 (en) 2006-04-27
NO20071600L (no) 2007-07-11
PL1805305T3 (pl) 2009-06-30
SI1805305T1 (sl) 2009-06-30
AU2005296360B2 (en) 2010-06-10
SI1805306T1 (sl) 2009-06-30
EP1805305A1 (en) 2007-07-11
WO2006043810A1 (en) 2006-04-27
EP1805305B1 (en) 2009-01-07
ATE420172T1 (de) 2009-01-15
JP2008517903A (ja) 2008-05-29
WO2006043809A1 (en) 2006-04-27
DK1805307T3 (da) 2009-05-04
DE602005012420D1 (de) 2009-03-05
ES2318550T3 (es) 2009-05-01
DE602005012304D1 (de) 2009-02-26
PL1805306T3 (pl) 2009-06-30
DK1805305T3 (da) 2009-11-23
NO20071601L (no) 2007-06-21
PL1805307T3 (pl) 2009-06-30
ATE420173T1 (de) 2009-01-15
ES2318548T3 (es) 2009-05-01
EP1805307A1 (en) 2007-07-11
CA2584633C (en) 2016-11-22
US20070224680A1 (en) 2007-09-27
DK1805306T3 (da) 2009-04-20
DE602005012303D1 (de) 2009-02-26
EP1805307B1 (en) 2009-01-14
EP1805306A1 (en) 2007-07-11
JP2008517904A (ja) 2008-05-29
WO2006043811A1 (en) 2006-04-27
ES2318549T3 (es) 2009-05-01

Similar Documents

Publication Publication Date Title
WO2008069824A3 (en) Compositions and methods for transport of molecules with enhanced release properties across biological barriers
HK1186406A1 (en) Method and carrier complexes for delivering molecules to cells
IN2014DN09128A (sl)
WO2011013130A3 (en) Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
NZ716641A (en) Process for preparing maytansinoid antibody conjugates
WO2010123482A3 (en) High charge density structures, including carbon-based nanostructures and applications thereof
IL188383A0 (en) Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals
WO2006124737A3 (en) Molecular constructs suitable for targeted conjugates
WO2009023320A3 (en) Modular linkers for conjugation of organic substances to substantially inorganic substances and methods of manufacture and use thereof
WO2007005941A3 (en) Liver targeted conjugates
WO2009139863A3 (en) Chimeric small molecules for the recruitment of antibodies to cancer cells
IL189595A0 (en) Hydrogel functionalized with a polymerizable moiety and their uses as biosensors or bioreactors
WO2003035011A8 (en) Multidrug multiligand conjugates for targeted drug delivery
PL1805307T3 (pl) Ochrona biologicznie aktywnych cząsteczek przy użyciu amfifili
DE602005021886D1 (de) Kopplungsmittel mit photolabiler schutzgruppe und verwendungen dafür, wie etwa zur funktionalisierung von festkörperträgern
BRPI0507664A (pt) compostos com atividade antitumor
WO2008146854A1 (ja) 抗モータリン抗体のパラトープ及びエピトープ
WO2007008247A3 (en) Platinum complexes for targeted drug delivery
WO2002091991A3 (en) Substantially homogeneous bio-affecting material having a pre-determined ratio of bioaffecting component to cell targeting component, the method for making such a material and the method of its use
PL1799692T3 (pl) Borowane metaloftalocyjaniny, sposób ich wytwarzania, zawierające je środki farmaceutyczne i ich zastosowanie
WO2005023312A3 (en) Methods for transfecting cells using dna minor groove binding agents
WO2006110623A3 (en) Targeted cholera toxin for treatment of persistent or chonic pain
Negrete DNA nanostructure immobilization to lithographic DNA arrays
Knaus A Present for My Teacher
NL1025224A1 (nl) Systeem voor bevestiging van een zadel op een voertuig, in het bijzonder een fiets.