NO20071601L - Beskyttelse av biologisk aktive molekyler ved anvendelse av amfifiler - Google Patents

Beskyttelse av biologisk aktive molekyler ved anvendelse av amfifiler

Info

Publication number
NO20071601L
NO20071601L NO20071601A NO20071601A NO20071601L NO 20071601 L NO20071601 L NO 20071601L NO 20071601 A NO20071601 A NO 20071601A NO 20071601 A NO20071601 A NO 20071601A NO 20071601 L NO20071601 L NO 20071601L
Authority
NO
Norway
Prior art keywords
molecule
amphiphiles
protection
biologically active
active molecules
Prior art date
Application number
NO20071601A
Other languages
English (en)
Inventor
Marcel Herman Jozef Ruiters
Original Assignee
Synvolux Ip Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL1027311A external-priority patent/NL1027311C2/nl
Priority claimed from NL1027417A external-priority patent/NL1027417C2/nl
Application filed by Synvolux Ip Bv filed Critical Synvolux Ip Bv
Publication of NO20071601L publication Critical patent/NO20071601L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Det beskrives en fremgangsmåte for beskyttelse av en biologisk aktiv forbindelse mot effekten av for eksempel enzymer, kjemikalier, oksygen, radikaler eller sollys, over et tidsrom på dager, uker og måneder. Fremgangsmåten kjennetegnes ved at den omfatter det trinn å bringe den biologisk aktive forbindelse i kontakt med minst ett SAINT-molekyl. Derved oppnås god beskyttelse mot den biologisk aktive forbindelse.
NO20071601A 2004-10-21 2007-03-27 Beskyttelse av biologisk aktive molekyler ved anvendelse av amfifiler NO20071601L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL1027311A NL1027311C2 (nl) 2004-10-21 2004-10-21 Vehikel voor transport van een DNA-modificerend enzym naar een genoom.
NL1027417A NL1027417C2 (nl) 2004-10-21 2004-11-04 Vehikel voor transport van een gekozen molecuul naar een cel.
NL1027479A NL1027479C2 (nl) 2004-10-21 2004-11-10 Bescherming van biologisch actieve moleculen met behulp van amphifielen.
PCT/NL2005/000752 WO2006043809A1 (en) 2004-10-21 2005-10-20 Protection of biologically active molecules using amphiphiles

Publications (1)

Publication Number Publication Date
NO20071601L true NO20071601L (no) 2007-06-21

Family

ID=35583431

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20071600A NO20071600L (no) 2004-10-21 2007-03-27 Baerer for transport av et valgt molekyl til en celle.
NO20071599A NO20071599L (no) 2004-10-21 2007-03-27 Baerer for transport av et DNA-modifeserende enzym til et genom.
NO20071601A NO20071601L (no) 2004-10-21 2007-03-27 Beskyttelse av biologisk aktive molekyler ved anvendelse av amfifiler

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20071600A NO20071600L (no) 2004-10-21 2007-03-27 Baerer for transport av et valgt molekyl til en celle.
NO20071599A NO20071599L (no) 2004-10-21 2007-03-27 Baerer for transport av et DNA-modifeserende enzym til et genom.

Country Status (16)

Country Link
US (4) US20070225230A1 (no)
EP (3) EP1805305B1 (no)
JP (2) JP2008517903A (no)
KR (1) KR20070073796A (no)
AT (3) ATE420172T1 (no)
AU (1) AU2005296360B2 (no)
CA (2) CA2584633C (no)
DE (3) DE602005012420D1 (no)
DK (3) DK1805305T3 (no)
ES (3) ES2318550T3 (no)
NL (1) NL1027479C2 (no)
NO (3) NO20071600L (no)
PL (3) PL1805307T3 (no)
PT (3) PT1805307E (no)
SI (3) SI1805306T1 (no)
WO (3) WO2006043809A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008295666B2 (en) * 2007-09-07 2013-05-16 Synvolux Ip B.V. Improved liposomes and uses thereof
DE102008032594A1 (de) 2008-07-11 2010-01-14 Qiagen Gmbh Transfektionslösung

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077211A (en) * 1988-07-06 1991-12-31 Applied Genetics, Inc. Purification and administration of dna repair enzymes
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
JPH07500820A (ja) * 1991-09-05 1995-01-26 ユニバーシティ オブ コネティカット ポリヌクレオチド又はオリゴヌクレオチドの細胞への標的を定めた送達
DE69536153D1 (de) * 1994-11-17 2011-05-05 Ich Productions Ltd Internalisierung von dna, unter verwendung von konjugaten des poly-l-lysins und eines peptidligands des integrin-rezeptors
NL1000884C2 (nl) * 1995-07-25 1997-01-28 Univ Groningen Transportvehikels voor macromoleculen.
US6726894B1 (en) * 1995-07-25 2004-04-27 Synvolux Ip B.V. Transport vehicles for macromolecules
US5958894A (en) * 1997-04-04 1999-09-28 Megabios Corporation Amphiphilic biguanide derivatives
WO2002096367A2 (en) * 2001-05-30 2002-12-05 Targesome, Inc. Targeted multivalent macromolecules
GB0117964D0 (en) * 2001-07-24 2001-09-19 Imp College Innovations Ltd Control of gene expression
WO2003011345A1 (en) * 2001-07-27 2003-02-13 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
GB0124391D0 (en) * 2001-10-11 2001-11-28 Gene Expression Technologies L Control of gene expression
WO2003093449A2 (en) * 2002-05-06 2003-11-13 Nucleonics, Inc. Methods for delivery of nucleic acids
JP2006509010A (ja) * 2002-12-05 2006-03-16 インペリアル・カレッジ・イノベイションズ・リミテッド アポトーシスの制御
CA2524255C (en) * 2003-03-21 2014-02-11 Academisch Ziekenhuis Leiden Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
ITMI20030821A1 (it) * 2003-04-18 2004-10-19 Internat Ct For Genetic En Gineering And Polipeptidi chimerici e loro uso.

Also Published As

Publication number Publication date
DK1805307T3 (da) 2009-05-04
DE602005012304D1 (de) 2009-02-26
PL1805306T3 (pl) 2009-06-30
EP1805307B1 (en) 2009-01-14
PT1805305E (pt) 2009-04-13
PL1805305T3 (pl) 2009-06-30
US20070224589A1 (en) 2007-09-27
NO20071599L (no) 2007-06-26
DK1805305T3 (da) 2009-11-23
ES2318550T3 (es) 2009-05-01
CA2584633C (en) 2016-11-22
ES2318548T3 (es) 2009-05-01
AU2005296360B2 (en) 2010-06-10
EP1805305A1 (en) 2007-07-11
SI1805306T1 (sl) 2009-06-30
NO20071600L (no) 2007-07-11
DK1805306T3 (da) 2009-04-20
EP1805306B1 (en) 2009-01-07
KR20070073796A (ko) 2007-07-10
PT1805307E (pt) 2009-04-13
EP1805305B1 (en) 2009-01-07
ATE420173T1 (de) 2009-01-15
AU2005296360A1 (en) 2006-04-27
ATE420172T1 (de) 2009-01-15
WO2006043810A1 (en) 2006-04-27
EP1805306A1 (en) 2007-07-11
PL1805307T3 (pl) 2009-06-30
ES2318549T3 (es) 2009-05-01
JP2008517903A (ja) 2008-05-29
PT1805306E (pt) 2009-04-13
WO2006043809A1 (en) 2006-04-27
ATE420954T1 (de) 2009-01-15
CA2583860A1 (en) 2006-04-27
DE602005012303D1 (de) 2009-02-26
NL1027479C2 (nl) 2006-05-01
US20070225230A1 (en) 2007-09-27
US20080085273A1 (en) 2008-04-10
WO2006043811A1 (en) 2006-04-27
CA2584633A1 (en) 2006-04-27
SI1805305T1 (sl) 2009-06-30
US20070224680A1 (en) 2007-09-27
JP2008517904A (ja) 2008-05-29
EP1805307A1 (en) 2007-07-11
SI1805307T1 (sl) 2009-06-30
DE602005012420D1 (de) 2009-03-05

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