SI1778623T1 - Derivati 1-fenilalkankarboksilnih kislin za zdravljenje nevrodegeneratvnih bolezni - Google Patents
Derivati 1-fenilalkankarboksilnih kislin za zdravljenje nevrodegeneratvnih bolezniInfo
- Publication number
- SI1778623T1 SI1778623T1 SI200530328T SI200530328T SI1778623T1 SI 1778623 T1 SI1778623 T1 SI 1778623T1 SI 200530328 T SI200530328 T SI 200530328T SI 200530328 T SI200530328 T SI 200530328T SI 1778623 T1 SI1778623 T1 SI 1778623T1
- Authority
- SI
- Slovenia
- Prior art keywords
- treatment
- neurodegenerative diseases
- derivatives
- phenylalkanecarboxylic acids
- phenylalkanecarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04425604 | 2004-08-03 | ||
| EP05767873A EP1778623B1 (en) | 2004-08-03 | 2005-07-26 | Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1778623T1 true SI1778623T1 (sl) | 2008-10-31 |
Family
ID=35462580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200530328T SI1778623T1 (sl) | 2004-08-03 | 2005-07-26 | Derivati 1-fenilalkankarboksilnih kislin za zdravljenje nevrodegeneratvnih bolezni |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7531692B2 (sl) |
| EP (1) | EP1778623B1 (sl) |
| JP (1) | JP4866851B2 (sl) |
| KR (1) | KR101156393B1 (sl) |
| CN (1) | CN1984878B (sl) |
| AT (1) | ATE399758T1 (sl) |
| AU (1) | AU2005270949B2 (sl) |
| BR (1) | BRPI0513647A (sl) |
| CA (1) | CA2576009C (sl) |
| CY (1) | CY1110401T1 (sl) |
| DE (1) | DE602005007912D1 (sl) |
| DK (1) | DK1778623T3 (sl) |
| ES (1) | ES2309778T3 (sl) |
| HK (1) | HK1104280A1 (sl) |
| HR (1) | HRP20080494T3 (sl) |
| NO (1) | NO339921B1 (sl) |
| PL (1) | PL1778623T3 (sl) |
| PT (1) | PT1778623E (sl) |
| RS (1) | RS50601B (sl) |
| SI (1) | SI1778623T1 (sl) |
| WO (1) | WO2006016219A2 (sl) |
| ZA (1) | ZA200700945B (sl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004016729D1 (de) * | 2003-02-21 | 2008-11-06 | Chiesi Farma Spa | 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen |
| EP2560942B1 (en) | 2010-04-21 | 2014-11-26 | Chiesi Farmaceutici S.p.A. | 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid derivatives for the therapy of transthyretin amyloidosis |
| KR20130080795A (ko) | 2010-06-04 | 2013-07-15 | 키에시 파르마슈티시 엣스. 피. 에이. | 프리온 질환의 치료를 위한 1-(2-플루오로비페닐-4-일)-시클로프로판카복실산 유도체 |
| US9592210B2 (en) | 2011-12-22 | 2017-03-14 | Chiesi Farmaceutici S.P.A. | 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment |
| EP2834214A1 (en) | 2012-04-04 | 2015-02-11 | Chiesi Farmaceutici S.p.A. | Derivatives of 1-(2-halo-biphenyl-4-yl)- alkanecarboxylic acids for the treatment of neurodegenerative diseases |
| WO2015181094A1 (en) | 2014-05-26 | 2015-12-03 | Chiesi Farmaceutici S.P.A. | 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid derivatives for the treatment of down's syndrome |
| WO2019099314A1 (en) | 2017-11-14 | 2019-05-23 | Merck Sharp & Dohme Corp. | Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors |
| WO2019099294A1 (en) | 2017-11-14 | 2019-05-23 | Merck Sharp & Dohme Corp. | Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283489B1 (it) * | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
| US6117901A (en) * | 1996-11-22 | 2000-09-12 | Athena Neurosciences, Inc. | N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use |
| US6211235B1 (en) * | 1996-11-22 | 2001-04-03 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting β-amyloid peptide release and/or its synthesis |
| US6191166B1 (en) * | 1997-11-21 | 2001-02-20 | Elan Pharmaceuticals, Inc. | Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis |
| WO1998034115A1 (en) | 1997-02-04 | 1998-08-06 | Trega Biosciences, Inc. | 4-substituted-quinoline derivatives and 4-substitute-quinoline combinatorial libraries |
| US5994379A (en) | 1998-02-13 | 1999-11-30 | Merck Frosst Canada, Inc. | Bisaryl COX-2 inhibiting compounds, compositions and methods of use |
| FR2842523A1 (fr) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| DE602004016729D1 (de) | 2003-02-21 | 2008-11-06 | Chiesi Farma Spa | 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen |
-
2005
- 2005-07-26 KR KR1020067027604A patent/KR101156393B1/ko not_active IP Right Cessation
- 2005-07-26 SI SI200530328T patent/SI1778623T1/sl unknown
- 2005-07-26 ZA ZA200700945A patent/ZA200700945B/xx unknown
- 2005-07-26 ES ES05767873T patent/ES2309778T3/es active Active
- 2005-07-26 PL PL05767873T patent/PL1778623T3/pl unknown
- 2005-07-26 WO PCT/IB2005/002189 patent/WO2006016219A2/en active Application Filing
- 2005-07-26 PT PT05767873T patent/PT1778623E/pt unknown
- 2005-07-26 CN CN200580023905XA patent/CN1984878B/zh not_active Expired - Fee Related
- 2005-07-26 BR BRPI0513647-4A patent/BRPI0513647A/pt not_active IP Right Cessation
- 2005-07-26 AT AT05767873T patent/ATE399758T1/de active
- 2005-07-26 CA CA2576009A patent/CA2576009C/en not_active Expired - Fee Related
- 2005-07-26 JP JP2007524411A patent/JP4866851B2/ja not_active Expired - Fee Related
- 2005-07-26 DE DE602005007912T patent/DE602005007912D1/de active Active
- 2005-07-26 EP EP05767873A patent/EP1778623B1/en active Active
- 2005-07-26 RS RSP-2008/0392A patent/RS50601B/sr unknown
- 2005-07-26 AU AU2005270949A patent/AU2005270949B2/en not_active Ceased
- 2005-07-26 US US11/572,974 patent/US7531692B2/en not_active Expired - Fee Related
- 2005-07-26 DK DK05767873T patent/DK1778623T3/da active
-
2007
- 2007-01-31 NO NO20070665A patent/NO339921B1/no not_active IP Right Cessation
- 2007-08-28 HK HK07109391.9A patent/HK1104280A1/xx not_active IP Right Cessation
-
2008
- 2008-09-04 CY CY20081100961T patent/CY1110401T1/el unknown
- 2008-10-01 HR HR20080494T patent/HRP20080494T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005007912D1 (de) | 2008-08-14 |
| PL1778623T3 (pl) | 2008-12-31 |
| HRP20080494T3 (en) | 2008-11-30 |
| AU2005270949A1 (en) | 2006-02-16 |
| WO2006016219A2 (en) | 2006-02-16 |
| HK1104280A1 (en) | 2008-01-11 |
| CN1984878A (zh) | 2007-06-20 |
| CY1110401T1 (el) | 2015-04-29 |
| JP2008509124A (ja) | 2008-03-27 |
| CN1984878B (zh) | 2011-06-08 |
| DK1778623T3 (da) | 2008-10-20 |
| EP1778623A2 (en) | 2007-05-02 |
| JP4866851B2 (ja) | 2012-02-01 |
| PT1778623E (pt) | 2008-09-29 |
| CA2576009C (en) | 2013-02-26 |
| NO20070665L (no) | 2007-05-02 |
| CA2576009A1 (en) | 2006-02-16 |
| AU2005270949B2 (en) | 2011-02-03 |
| EP1778623B1 (en) | 2008-07-02 |
| US20080096968A1 (en) | 2008-04-24 |
| NO339921B1 (no) | 2017-02-13 |
| US7531692B2 (en) | 2009-05-12 |
| ES2309778T3 (es) | 2008-12-16 |
| ZA200700945B (en) | 2008-09-25 |
| KR101156393B1 (ko) | 2012-06-13 |
| RS50601B (sr) | 2010-05-07 |
| BRPI0513647A (pt) | 2008-05-13 |
| ATE399758T1 (de) | 2008-07-15 |
| KR20070038982A (ko) | 2007-04-11 |
| WO2006016219A3 (en) | 2006-04-27 |
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