SI1697350T1 - Modulatorji jedrnega receptorja tricikličnih steroidnih hormonov - Google Patents
Modulatorji jedrnega receptorja tricikličnih steroidnih hormonovInfo
- Publication number
- SI1697350T1 SI1697350T1 SI200430840T SI200430840T SI1697350T1 SI 1697350 T1 SI1697350 T1 SI 1697350T1 SI 200430840 T SI200430840 T SI 200430840T SI 200430840 T SI200430840 T SI 200430840T SI 1697350 T1 SI1697350 T1 SI 1697350T1
- Authority
- SI
- Slovenia
- Prior art keywords
- receptor modulators
- nuclear receptor
- steroid hormone
- hormone nuclear
- tricyclic steroid
- Prior art date
Links
Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53128303P | 2003-12-19 | 2003-12-19 | |
EP04811084A EP1697350B1 (en) | 2003-12-19 | 2004-12-08 | Tricyclic steroid hormone nuclear receptor modulators |
PCT/US2004/038233 WO2005066161A1 (en) | 2003-12-19 | 2004-12-08 | Tricyclic steroid hormone nuclear receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1697350T1 true SI1697350T1 (sl) | 2008-12-31 |
Family
ID=34748755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200430840T SI1697350T1 (sl) | 2003-12-19 | 2004-12-08 | Modulatorji jedrnega receptorja tricikličnih steroidnih hormonov |
Country Status (21)
Country | Link |
---|---|
US (1) | US7803814B2 (sl) |
EP (1) | EP1697350B1 (sl) |
JP (1) | JP4846596B2 (sl) |
CN (1) | CN1918151A (sl) |
AR (1) | AR046951A1 (sl) |
AT (1) | ATE399163T1 (sl) |
AU (1) | AU2004312293A1 (sl) |
BR (1) | BRPI0416882A (sl) |
CA (1) | CA2549053C (sl) |
CY (1) | CY1108309T1 (sl) |
DE (1) | DE602004014640D1 (sl) |
DK (1) | DK1697350T3 (sl) |
ES (1) | ES2308296T3 (sl) |
IL (1) | IL175996A0 (sl) |
MX (1) | MXPA06007055A (sl) |
NO (1) | NO20063329L (sl) |
PL (1) | PL1697350T3 (sl) |
PT (1) | PT1697350E (sl) |
SI (1) | SI1697350T1 (sl) |
WO (1) | WO2005066161A1 (sl) |
ZA (1) | ZA200604889B (sl) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200400816A (en) * | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
CA2594264C (en) * | 2004-12-23 | 2013-05-21 | Athersys, Inc. | 4-piperidinol tertiary amines as histamine 3 receptor inhibitors for the treatment of obesity and other cns disorders |
DE102005022020A1 (de) * | 2005-05-12 | 2006-11-23 | Merckle Gmbh | Dibenzocycloheptanverbindungen und pharmazeutische Mittel, welche diese Verbindungen enthalten |
TWI385161B (zh) | 2006-02-02 | 2013-02-11 | Mitsubishi Tanabe Pharma Corp | 含氮雜雙環化合物 |
US8034940B2 (en) | 2006-08-09 | 2011-10-11 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
MY145795A (en) * | 2006-10-31 | 2012-04-30 | Pfizer Prod Inc | Pyrazoline compounds |
TWI431010B (zh) | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
JP2011525474A (ja) * | 2008-01-11 | 2011-09-22 | イーライ リリー アンド カンパニー | リウマチの治療のための糖質コルチコイド受容体調節因子としての(E)−N−{3−[1−(8−フルオロ−11H−10−オキサ−1−アザ−ジベンゾ[a,d]シクロヘプテン−5−イリデン)プロピル]フェニル}メタンスルホンアミド |
EP2308880A4 (en) | 2008-07-03 | 2012-06-06 | Kyowa Hakko Kirin Co Ltd | TETRACYCLIC CONNECTION |
KR101312179B1 (ko) * | 2009-03-12 | 2013-09-26 | 일라이 릴리 앤드 캄파니 | 미네랄로코르티코이드 수용체 길항제 및 사용 방법 |
WO2011081173A1 (ja) * | 2009-12-29 | 2011-07-07 | 協和発酵キリン株式会社 | 四環系化合物 |
JP6148175B2 (ja) | 2010-05-10 | 2017-06-14 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 網膜中および/または網膜下における液体貯留の処置のための方法および組成物 |
JP6180930B2 (ja) | 2010-06-16 | 2017-08-16 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 創傷治癒過程における再上皮化を刺激するための方法及び組成物 |
EP2638012A1 (en) * | 2010-11-10 | 2013-09-18 | Boehringer Ingelheim International GmbH | Pyridyl ureas as mineralocorticoid receptor antagonists |
WO2013018899A1 (ja) * | 2011-08-03 | 2013-02-07 | 協和発酵キリン株式会社 | ジベンゾオキセピン誘導体 |
CN117653636B (zh) * | 2021-04-12 | 2024-04-26 | 上海瑛派药业有限公司 | 含稠合双环类化合物的抗癌药及该化合物的制药用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3730258A1 (de) | 1986-09-10 | 1988-04-07 | Canon Kk | Elektrophotographisches lichtempfindliches aufzeichnungsmaterial, 5h-dibenzo(a,d)cycloheptanylidenderivat, 5h-dibenzo(a,d)cycloheptenylidenderivat und verfahren zu ihrer herstellung |
JPH01161245A (ja) | 1987-12-18 | 1989-06-23 | Canon Inc | 電子写真感光体 |
CA1338625C (en) | 1988-06-09 | 1996-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5093210A (en) | 1989-06-30 | 1992-03-03 | Ricoh Company, Ltd. | Electroluminescent device |
JPH0446352A (ja) | 1990-06-14 | 1992-02-17 | Minolta Camera Co Ltd | 感光体 |
CO4980885A1 (es) * | 1997-12-29 | 2000-11-27 | Ortho Mcneil Pharm Inc | Compuestos de trifenilpropanamida utiles en el tratamiento de inflamaciones y metodos para preparar dicho compuesto |
JP2002541144A (ja) | 1999-01-26 | 2002-12-03 | ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド | 医薬的に活性のある化合物及びその使用方法 |
EP1467979B1 (en) | 2001-12-19 | 2008-08-13 | Bristol-Myers Squibb Company | Fused heterocyclic compounds and analogs thereof modulators of nuclear hormone receptor function |
US7250442B2 (en) * | 2002-03-15 | 2007-07-31 | Eli Lilly And Company | Dihydroindol-2-one derivatives as steroid hormone nuclear receptor modulators |
TW200400816A (en) * | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
-
2004
- 2004-12-08 DK DK04811084T patent/DK1697350T3/da active
- 2004-12-08 CA CA2549053A patent/CA2549053C/en not_active Expired - Fee Related
- 2004-12-08 JP JP2006545655A patent/JP4846596B2/ja not_active Expired - Fee Related
- 2004-12-08 US US10/576,761 patent/US7803814B2/en not_active Expired - Fee Related
- 2004-12-08 PT PT04811084T patent/PT1697350E/pt unknown
- 2004-12-08 EP EP04811084A patent/EP1697350B1/en not_active Not-in-force
- 2004-12-08 SI SI200430840T patent/SI1697350T1/sl unknown
- 2004-12-08 DE DE602004014640T patent/DE602004014640D1/de active Active
- 2004-12-08 AT AT04811084T patent/ATE399163T1/de not_active IP Right Cessation
- 2004-12-08 AU AU2004312293A patent/AU2004312293A1/en not_active Abandoned
- 2004-12-08 MX MXPA06007055A patent/MXPA06007055A/es unknown
- 2004-12-08 CN CNA2004800418534A patent/CN1918151A/zh active Pending
- 2004-12-08 BR BRPI0416882-8A patent/BRPI0416882A/pt not_active Application Discontinuation
- 2004-12-08 WO PCT/US2004/038233 patent/WO2005066161A1/en active Application Filing
- 2004-12-08 PL PL04811084T patent/PL1697350T3/pl unknown
- 2004-12-08 ES ES04811084T patent/ES2308296T3/es active Active
- 2004-12-17 AR ARP040104730A patent/AR046951A1/es unknown
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2006
- 2006-05-29 IL IL175996A patent/IL175996A0/en unknown
- 2006-06-13 ZA ZA200604889A patent/ZA200604889B/en unknown
- 2006-07-18 NO NO20063329A patent/NO20063329L/no not_active Application Discontinuation
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2008
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Also Published As
Publication number | Publication date |
---|---|
US7803814B2 (en) | 2010-09-28 |
DE602004014640D1 (de) | 2008-08-07 |
US20070037788A1 (en) | 2007-02-15 |
EP1697350A1 (en) | 2006-09-06 |
JP4846596B2 (ja) | 2011-12-28 |
JP2007515431A (ja) | 2007-06-14 |
MXPA06007055A (es) | 2007-01-30 |
IL175996A0 (en) | 2006-10-05 |
CA2549053C (en) | 2012-08-28 |
PT1697350E (pt) | 2008-09-18 |
WO2005066161A1 (en) | 2005-07-21 |
CA2549053A1 (en) | 2005-07-21 |
ZA200604889B (en) | 2007-11-28 |
ATE399163T1 (de) | 2008-07-15 |
CN1918151A (zh) | 2007-02-21 |
AU2004312293A1 (en) | 2005-07-21 |
NO20063329L (no) | 2006-09-14 |
CY1108309T1 (el) | 2014-02-12 |
AR046951A1 (es) | 2006-01-04 |
ES2308296T3 (es) | 2008-12-01 |
BRPI0416882A (pt) | 2007-02-27 |
EP1697350B1 (en) | 2008-06-25 |
DK1697350T3 (da) | 2008-10-13 |
PL1697350T3 (pl) | 2008-11-28 |
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