SI1601646T1 - 2-substitirani vitamin d analogi in njihova terapevtska uporaba - Google Patents

2-substitirani vitamin d analogi in njihova terapevtska uporaba

Info

Publication number
SI1601646T1
SI1601646T1 SI200431733T SI200431733T SI1601646T1 SI 1601646 T1 SI1601646 T1 SI 1601646T1 SI 200431733 T SI200431733 T SI 200431733T SI 200431733 T SI200431733 T SI 200431733T SI 1601646 T1 SI1601646 T1 SI 1601646T1
Authority
SI
Slovenia
Prior art keywords
analogues
vitamin
therapeutic uses
substituted vitamin
alkyl
Prior art date
Application number
SI200431733T
Other languages
English (en)
Inventor
Roger Bouillon
Annemieke Verstuyf
Maurits Vandewalle
Clercq Pierre De
Original Assignee
K U Leuver Res And Dev
Univ Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by K U Leuver Res And Dev, Univ Gent filed Critical K U Leuver Res And Dev
Publication of SI1601646T1 publication Critical patent/SI1601646T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200431733T 2003-03-10 2004-03-10 2-substitirani vitamin d analogi in njihova terapevtska uporaba SI1601646T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0305332.9A GB0305332D0 (en) 2003-03-10 2003-03-10 Biological evaluation of novel vitamin D analogues
EP04718886A EP1601646B1 (en) 2003-03-10 2004-03-10 2-substituted vitamin d analogues and their therapeutic uses
PCT/BE2004/000037 WO2004080922A2 (en) 2003-03-10 2004-03-10 Substituted vitamin d analogues and their therapeutic uses

Publications (1)

Publication Number Publication Date
SI1601646T1 true SI1601646T1 (sl) 2011-11-30

Family

ID=9954381

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431733T SI1601646T1 (sl) 2003-03-10 2004-03-10 2-substitirani vitamin d analogi in njihova terapevtska uporaba

Country Status (14)

Country Link
US (1) US20060189576A1 (sl)
EP (1) EP1601646B1 (sl)
JP (1) JP2006519788A (sl)
AT (1) ATE517864T1 (sl)
AU (1) AU2004220477B8 (sl)
CA (1) CA2518531A1 (sl)
CY (1) CY1111843T1 (sl)
DK (1) DK1601646T3 (sl)
ES (1) ES2368064T3 (sl)
GB (1) GB0305332D0 (sl)
PL (1) PL1601646T3 (sl)
PT (1) PT1601646E (sl)
SI (1) SI1601646T1 (sl)
WO (1) WO2004080922A2 (sl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008520705A (ja) 2004-11-22 2008-06-19 ウィスコンシン・アルムニ・リサーチ・ファウンデーション ２−メチレン−１９−ノル−１α−ヒドロキシ−１７−エン−ホモプレグナカルシフェロールおよびその使用
MX2007006263A (es) * 2004-11-22 2007-07-10 Wisconsin Alumni Res Found Analogos 2a-metil y 2??-metil de 19,26,27-trinor-(20s)-1a- hidroxivitamina d3 y sus usos.
JP2008520703A (ja) * 2004-11-22 2008-06-19 ウィスコンシン・アルムニ・リサーチ・ファウンデーション ２α−メチル−１９−ノル−（２０Ｓ）−１α−ヒドロキシ−ビスホモプレグナカルシフェロールおよびその使用
WO2006060885A1 (en) * 2004-12-07 2006-06-15 K.U.Leuven Research & Development 7-(2-cyclohexylidene-ethylidene)-spiro[5.5]undecanes useful for making pharmaceutical compositions
MX2007013558A (es) 2005-05-03 2008-01-24 Wisconsin Alumni Res Found Compuestos de 19,26,27-trinor-1a,25-dihidroxivitamina d3.
US7528122B2 (en) 2006-02-02 2009-05-05 Wisconsin Alumni Research Foundation Vitamin D analog—NEL, methods and uses thereof
US7803789B2 (en) 2006-02-02 2010-09-28 Wisconsin Alumni Research Foundation Vitamin D analog—RAK, methods and uses thereof
US7648973B2 (en) 2006-04-06 2010-01-19 Wisconsin Alumni Research Foundation 2-methylene-1α,25-dihydroxy-19,21-dinorvitamin D3 analogs and uses thereof
EP2021321B1 (en) 2006-04-06 2012-06-20 Wisconsin Alumni Research Foundation 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin d3 and uses thereof
CA2646911A1 (en) 2006-04-06 2008-03-27 Hector F. Deluca 2- substituted-1alpha, 25-dihydroxy-19,26,27-trinor vitamin d analogs and uses thereof
AU2007300214A1 (en) 2006-09-28 2008-04-03 Wisconsin Alumni Research Foundation 2-methylene-(20R,25S)-19,27-dinor-(22E)-vitamin D analogs
DK2263677T3 (da) * 2009-05-20 2011-06-06 Hybrigenics Sa Nye terapeutiske anvendelser af inecalcitol
CA2777938C (en) * 2009-10-21 2017-11-14 Wisconsin Alumni Research Foundation Method of preventing type 1 diabetes
DK2407154T3 (da) 2010-07-15 2013-03-04 Hybrigenics Sa Formuleringer af 14-epi-analoger af D-vitamin
EP2407152A1 (en) 2010-07-15 2012-01-18 Hybrigenics S.A. Formulations of 14-epi-analogues of vitamin D
US20120015913A1 (en) * 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
WO2012118154A1 (ja) * 2011-03-02 2012-09-07 学校法人日本大学 パーシャルアゴニスト活性を持つ新規ビタミンd受容体モジュレーター
US9616109B2 (en) 2014-10-22 2017-04-11 Extend Biosciences, Inc. Insulin vitamin D conjugates
JP6946182B2 (ja) 2014-10-22 2021-10-06 エクステンド バイオサイエンシズ インコーポレーテッドＥｘｔｅｎｄ Ｂｉｏｓｃｉｅｎｃｅｓ， Ｉｎｃ 治療用ビタミンｄコンジュゲート
CN104326922B (zh) * 2014-11-03 2016-08-17 成都百裕制药股份有限公司 替格瑞洛中间体(1r,2s)-2-(2,3-二氟苯基)环丙胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
NZ271332A (en) * 1993-07-09 2001-03-30 Theramex Vitamin D analogues and pharmaceutical use
US5936105A (en) * 1997-06-13 1999-08-10 Tetrionics, Inc. 14-EPI-19-nor-vitamin D compounds and methods
EP1286962B1 (en) * 2000-05-31 2008-06-25 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds

Also Published As

Publication number Publication date
WO2004080922A2 (en) 2004-09-23
EP1601646B1 (en) 2011-07-27
AU2004220477B2 (en) 2010-05-06
CY1111843T1 (el) 2015-10-07
WO2004080922A3 (en) 2004-12-09
DK1601646T3 (da) 2011-10-03
PL1601646T3 (pl) 2011-12-30
AU2004220477B8 (en) 2010-10-14
ATE517864T1 (de) 2011-08-15
US20060189576A1 (en) 2006-08-24
GB0305332D0 (en) 2003-04-09
JP2006519788A (ja) 2006-08-31
EP1601646A2 (en) 2005-12-07
PT1601646E (pt) 2011-09-16
ES2368064T3 (es) 2011-11-14
AU2004220477A1 (en) 2004-09-23
CA2518531A1 (en) 2004-09-23

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