SI1439220T1 - Imobilizirani biokatalizatorji, uporabnimi za izdelavo naravnih nukleozidov in modificiranih analogov z encimatskimi reakcijami transglikolizacije - Google Patents

Imobilizirani biokatalizatorji, uporabnimi za izdelavo naravnih nukleozidov in modificiranih analogov z encimatskimi reakcijami transglikolizacije

Info

Publication number
SI1439220T1
SI1439220T1 SI200330990T SI200330990T SI1439220T1 SI 1439220 T1 SI1439220 T1 SI 1439220T1 SI 200330990 T SI200330990 T SI 200330990T SI 200330990 T SI200330990 T SI 200330990T SI 1439220 T1 SI1439220 T1 SI 1439220T1
Authority
SI
Slovenia
Prior art keywords
usable
manufacture
natural nucleosides
biocatalysts
modified analogues
Prior art date
Application number
SI200330990T
Other languages
English (en)
Inventor
Giancarlo Tonon
Emanuele Capra
Gaetano Orsini
Gabriele Zuffi
Original Assignee
Adorkem Technology Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adorkem Technology Spa filed Critical Adorkem Technology Spa
Publication of SI1439220T1 publication Critical patent/SI1439220T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02003Uridine phosphorylase (2.4.2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/18Multi-enzyme systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/38Nucleosides
    • C12P19/385Pyrimidine nucleosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/02Pentosyltransferases (2.4.2)
    • C12Y204/02001Purine-nucleoside phosphorylase (2.4.2.1)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
SI200330990T 2003-01-16 2003-01-16 Imobilizirani biokatalizatorji, uporabnimi za izdelavo naravnih nukleozidov in modificiranih analogov z encimatskimi reakcijami transglikolizacije SI1439220T1 (sl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03425018A EP1439220B1 (en) 2003-01-16 2003-01-16 Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions

Publications (1)

Publication Number Publication Date
SI1439220T1 true SI1439220T1 (sl) 2007-12-31

Family

ID=32524299

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200330990T SI1439220T1 (sl) 2003-01-16 2003-01-16 Imobilizirani biokatalizatorji, uporabnimi za izdelavo naravnih nukleozidov in modificiranih analogov z encimatskimi reakcijami transglikolizacije

Country Status (9)

Country Link
US (1) US20040142438A1 (sl)
EP (1) EP1439220B1 (sl)
AT (1) ATE371021T1 (sl)
CY (1) CY1107015T1 (sl)
DE (1) DE60315790T2 (sl)
DK (1) DK1439220T3 (sl)
ES (1) ES2292927T3 (sl)
PT (1) PT1439220E (sl)
SI (1) SI1439220T1 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241586B2 (en) * 2005-02-17 2007-07-10 Medtronic Minimed, Inc. Polypeptide formulations and methods for making, using and characterizing them
CN100379859C (zh) * 2005-03-04 2008-04-09 上海秋之友生物科技有限公司 固定化核苷磷酸化酶微生物及其在合成嘌呤核苷中的应用
US20070065922A1 (en) * 2005-09-21 2007-03-22 Metkinen Oy Biocatalytic synthesis of aminodeoxy purine N9-beta-D-nucleosides containing 3-amino-3-deoxy-beta-D-ribofuranose, 3-amino-2,3-dideoxy-beta-D-ribofuranose, and 2-amino-2-deoxy-beta-D-ribofuranose as sugar moieties
DE602006012278D1 (de) * 2006-03-15 2010-04-01 Explora Lab Sa Verfahren zur Immobilisierung von Zellen auf Harzen
ES2335796T3 (es) * 2006-12-15 2010-04-05 Explora Laboratories Sa Metodo para la produccion de cladribina.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5314810A (en) * 1987-11-25 1994-05-24 Meiji Seika Kaisha, Ltd. Fructose transferring enzyme absorbed on a granular carrier for production of fructooligosaccharides
IL90600A0 (en) * 1988-06-16 1990-01-18 Du Pont Polynucleotide phosphorylase immobilized on epoxy-activated beads
US5187296A (en) * 1988-12-07 1993-02-16 Bromine Compounds Limited Cyanohydrination process
IL88618A (en) * 1988-12-07 1993-02-21 Bromine Compounds Ltd Chiral cyanohydrination of m-phenoxybenzaldehyde over polymer-supported cyclo (phenylalanyl- histidine)
WO1993003048A1 (en) * 1991-07-31 1993-02-18 Warner-Lambert Company Process for purifying pentostatin
JP4003093B2 (ja) * 1997-07-29 2007-11-07 東洋紡績株式会社 糖類の製造方法
ITMI20011537A1 (it) * 2001-07-19 2003-01-19 Pro Bio Sint Srl Transglicosilazione di nucleosidi mediante biocatalisi con enzimi immobilizzati e stabilizzati

Also Published As

Publication number Publication date
US20040142438A1 (en) 2004-07-22
PT1439220E (pt) 2007-11-28
DK1439220T3 (da) 2007-12-27
DE60315790T2 (de) 2008-06-05
DE60315790D1 (de) 2007-10-04
ES2292927T3 (es) 2008-03-16
EP1439220A1 (en) 2004-07-21
CY1107015T1 (el) 2012-09-26
EP1439220B1 (en) 2007-08-22
ATE371021T1 (de) 2007-09-15

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