SI1355906T1 - 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof - Google Patents
2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereofInfo
- Publication number
- SI1355906T1 SI1355906T1 SI200230096T SI200230096T SI1355906T1 SI 1355906 T1 SI1355906 T1 SI 1355906T1 SI 200230096 T SI200230096 T SI 200230096T SI 200230096 T SI200230096 T SI 200230096T SI 1355906 T1 SI1355906 T1 SI 1355906T1
- Authority
- SI
- Slovenia
- Prior art keywords
- preparation
- processes
- pharmaceutical compositions
- benzopyran derivatives
- benzopyran
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000000463 2H-chromenes Chemical class 0.000 title 1
- 125000000850 2H-chromenyl group Chemical class O1C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01101521A EP1229036B1 (en) | 2001-01-24 | 2001-01-24 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| EP01118682A EP1281710A1 (en) | 2001-08-03 | 2001-08-03 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| PCT/EP2002/000567 WO2002059113A1 (en) | 2001-01-24 | 2002-01-21 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| EP02703564A EP1355906B1 (en) | 2001-01-24 | 2002-01-21 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1355906T1 true SI1355906T1 (en) | 2005-06-30 |
Family
ID=26076450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230096T SI1355906T1 (en) | 2001-01-24 | 2002-01-21 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6951883B2 (cs) |
| EP (1) | EP1355906B1 (cs) |
| JP (1) | JP4332349B2 (cs) |
| CN (1) | CN1261431C (cs) |
| AT (1) | ATE286894T1 (cs) |
| AU (1) | AU2002237282B2 (cs) |
| BR (1) | BR0207066A (cs) |
| CA (1) | CA2435775A1 (cs) |
| CZ (1) | CZ20032014A3 (cs) |
| DE (1) | DE60202590T2 (cs) |
| DK (1) | DK1355906T3 (cs) |
| DZ (1) | DZ3459A1 (cs) |
| EA (1) | EA006158B1 (cs) |
| ES (1) | ES2236485T3 (cs) |
| HU (1) | HUP0401018A3 (cs) |
| IL (2) | IL157065A0 (cs) |
| MA (1) | MA26982A1 (cs) |
| MX (1) | MXPA03006505A (cs) |
| NO (1) | NO327808B1 (cs) |
| NZ (1) | NZ527144A (cs) |
| PL (1) | PL365062A1 (cs) |
| PT (1) | PT1355906E (cs) |
| SI (1) | SI1355906T1 (cs) |
| SK (1) | SK287086B6 (cs) |
| TN (1) | TNSN03043A1 (cs) |
| WO (1) | WO2002059113A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2436680B1 (en) * | 2004-09-21 | 2016-05-18 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| JP4913056B2 (ja) * | 2004-09-21 | 2012-04-11 | マーシャル エドワーズ，インコーポレーテッド | 置換クロマン誘導体、医薬品、および治療における使用 |
| AU2005201855B2 (en) * | 2004-09-21 | 2012-03-29 | Marshall Edwards, Inc. | Chroman derived compounds and formulations thereof for use in therapy |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| US7601855B2 (en) | 2004-09-21 | 2009-10-13 | Novogen Research Pty Ltd | Substituted chroman derivatives, medicaments and use in therapy |
| JP4976649B2 (ja) * | 2004-09-21 | 2012-07-18 | マーシャル エドワーズ，インク． | 化合物 |
| CN101444499B (zh) * | 2007-11-26 | 2012-12-05 | 湘北威尔曼制药股份有限公司 | 一种化合物及其组合物的新用途 |
| EP2635273B1 (en) | 2010-11-01 | 2020-01-08 | MEI Pharma, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
| EA031077B1 (ru) | 2013-06-19 | 2018-11-30 | Серагон Фармасьютикалз, Инк. | Модулятор рецептора эстрогена и его применения |
| EP3253208B1 (en) | 2015-02-02 | 2021-05-05 | MEI Pharma, Inc. | Combination therapies for use in the treatment of breast cancer |
| ES3039455T3 (en) * | 2016-11-17 | 2025-10-21 | Sanofi Sa | Novel substituted n-(3-fluoropropyl)-pyrrolidine compounds, processes for their preparation and therapeutic uses thereof |
| EP3681495A4 (en) * | 2017-09-15 | 2021-06-02 | Nyrada Pty Limited | TREATMENT OF EXCITOTOXICITY |
| CN112225716A (zh) * | 2020-10-30 | 2021-01-15 | 陕西嘉禾生物科技股份有限公司 | 一种鹰嘴豆牙素a的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3374245A (en) * | 1964-04-01 | 1968-03-19 | Ciba Geigy Corp | Unsaturated oxacycles |
| DE1518002C3 (de) * | 1965-01-02 | 1975-01-23 | Merck Patent Gmbh, 6100 Darmstadt | Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel |
| US5280040A (en) * | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US5985306A (en) * | 1996-10-28 | 1999-11-16 | Novo Nordisk A/S | (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes |
| JP2001502706A (ja) * | 1996-10-28 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | エストロゲン関連病あるいは症候群の予防または治療に有用な新規トランス―３，４クロマン誘導体 |
| US6153768A (en) * | 1996-12-13 | 2000-11-28 | C & C Research Laboratories | Benzopyran derivatives |
| KR20000001793A (ko) | 1998-06-13 | 2000-01-15 | 이경하 | 신규한 벤조피란 또는 티오벤조피란 유도체 |
| HK1041258B (en) | 1998-12-30 | 2003-12-12 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
-
2002
- 2002-01-21 CA CA002435775A patent/CA2435775A1/en not_active Abandoned
- 2002-01-21 DZ DZ023459A patent/DZ3459A1/fr active
- 2002-01-21 ES ES02703564T patent/ES2236485T3/es not_active Expired - Lifetime
- 2002-01-21 SK SK939-2003A patent/SK287086B6/sk not_active IP Right Cessation
- 2002-01-21 DE DE60202590T patent/DE60202590T2/de not_active Expired - Lifetime
- 2002-01-21 EA EA200300727A patent/EA006158B1/ru not_active IP Right Cessation
- 2002-01-21 MX MXPA03006505A patent/MXPA03006505A/es active IP Right Grant
- 2002-01-21 PT PT02703564T patent/PT1355906E/pt unknown
- 2002-01-21 SI SI200230096T patent/SI1355906T1/xx unknown
- 2002-01-21 WO PCT/EP2002/000567 patent/WO2002059113A1/en not_active Ceased
- 2002-01-21 PL PL02365062A patent/PL365062A1/xx not_active IP Right Cessation
- 2002-01-21 EP EP02703564A patent/EP1355906B1/en not_active Expired - Lifetime
- 2002-01-21 DK DK02703564T patent/DK1355906T3/da active
- 2002-01-21 CZ CZ20032014A patent/CZ20032014A3/cs unknown
- 2002-01-21 IL IL15706502A patent/IL157065A0/xx unknown
- 2002-01-21 BR BR0207066-9A patent/BR0207066A/pt not_active IP Right Cessation
- 2002-01-21 NZ NZ527144A patent/NZ527144A/en unknown
- 2002-01-21 AU AU2002237282A patent/AU2002237282B2/en not_active Ceased
- 2002-01-21 JP JP2002559415A patent/JP4332349B2/ja not_active Expired - Fee Related
- 2002-01-21 HU HU0401018A patent/HUP0401018A3/hu unknown
- 2002-01-21 US US10/466,118 patent/US6951883B2/en not_active Expired - Fee Related
- 2002-01-21 CN CNB02804066XA patent/CN1261431C/zh not_active Expired - Fee Related
- 2002-01-21 AT AT02703564T patent/ATE286894T1/de not_active IP Right Cessation
-
2003
- 2003-07-08 TN TNPCT/EP2002/000567A patent/TNSN03043A1/en unknown
- 2003-07-15 MA MA27236A patent/MA26982A1/fr unknown
- 2003-07-23 NO NO20033318A patent/NO327808B1/no not_active IP Right Cessation
- 2003-07-23 IL IL157065A patent/IL157065A/en not_active IP Right Cessation
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