IL157065A0 - 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof - Google Patents
2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereofInfo
- Publication number
- IL157065A0 IL157065A0 IL15706502A IL15706502A IL157065A0 IL 157065 A0 IL157065 A0 IL 157065A0 IL 15706502 A IL15706502 A IL 15706502A IL 15706502 A IL15706502 A IL 15706502A IL 157065 A0 IL157065 A0 IL 157065A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- processes
- pharmaceutical compositions
- benzopyran derivatives
- benzopyran
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000000463 2H-chromenes Chemical class 0.000 title 1
- 125000000850 2H-chromenyl group Chemical class O1C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01101521A EP1229036B1 (en) | 2001-01-24 | 2001-01-24 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| EP01118682A EP1281710A1 (en) | 2001-08-03 | 2001-08-03 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| PCT/EP2002/000567 WO2002059113A1 (en) | 2001-01-24 | 2002-01-21 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL157065A0 true IL157065A0 (en) | 2004-02-08 |
Family
ID=26076450
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15706502A IL157065A0 (en) | 2001-01-24 | 2002-01-21 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| IL157065A IL157065A (en) | 2001-01-24 | 2003-07-23 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL157065A IL157065A (en) | 2001-01-24 | 2003-07-23 | 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6951883B2 (cs) |
| EP (1) | EP1355906B1 (cs) |
| JP (1) | JP4332349B2 (cs) |
| CN (1) | CN1261431C (cs) |
| AT (1) | ATE286894T1 (cs) |
| AU (1) | AU2002237282B2 (cs) |
| BR (1) | BR0207066A (cs) |
| CA (1) | CA2435775A1 (cs) |
| CZ (1) | CZ20032014A3 (cs) |
| DE (1) | DE60202590T2 (cs) |
| DK (1) | DK1355906T3 (cs) |
| DZ (1) | DZ3459A1 (cs) |
| EA (1) | EA006158B1 (cs) |
| ES (1) | ES2236485T3 (cs) |
| HU (1) | HUP0401018A3 (cs) |
| IL (2) | IL157065A0 (cs) |
| MA (1) | MA26982A1 (cs) |
| MX (1) | MXPA03006505A (cs) |
| NO (1) | NO327808B1 (cs) |
| NZ (1) | NZ527144A (cs) |
| PL (1) | PL365062A1 (cs) |
| PT (1) | PT1355906E (cs) |
| SI (1) | SI1355906T1 (cs) |
| SK (1) | SK287086B6 (cs) |
| TN (1) | TNSN03043A1 (cs) |
| WO (1) | WO2002059113A1 (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4976649B2 (ja) * | 2004-09-21 | 2012-07-18 | マーシャル エドワーズ，インク． | 化合物 |
| EP1809618B1 (en) * | 2004-09-21 | 2013-07-17 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| AU2005201855B2 (en) * | 2004-09-21 | 2012-03-29 | Marshall Edwards, Inc. | Chroman derived compounds and formulations thereof for use in therapy |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| CA2581316C (en) * | 2004-09-21 | 2013-09-10 | Novogen Research Pty Ltd | Substituted chroman derivatives, medicaments and use in therapy |
| ES2377073T3 (es) * | 2004-09-21 | 2012-03-22 | Marshall Edwards, Inc. | Derivados de cromano sustituidos, medicamentos y utilización en terapia |
| CN101444499B (zh) * | 2007-11-26 | 2012-12-05 | 湘北威尔曼制药股份有限公司 | 一种化合物及其组合物的新用途 |
| CA2816322A1 (en) | 2010-11-01 | 2012-05-10 | Marshall Edwards, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
| JP6576916B2 (ja) | 2013-06-19 | 2019-09-18 | セラゴン ファーマシューティカルズ， インク． | エストロゲン受容体モジュレーター及びその使用 |
| EP3253208B1 (en) | 2015-02-02 | 2021-05-05 | MEI Pharma, Inc. | Combination therapies for use in the treatment of breast cancer |
| KR102477513B1 (ko) * | 2016-11-17 | 2022-12-16 | 사노피 | 신규 치환된 n-(3-플루오로프로필)-피롤리딘 화합물, 그의 제조 방법 및 그의 치료 용도 |
| EP3681495A4 (en) * | 2017-09-15 | 2021-06-02 | Nyrada Pty Limited | TREATMENT OF EXCITOTOXICITY |
| CN112225716A (zh) * | 2020-10-30 | 2021-01-15 | 陕西嘉禾生物科技股份有限公司 | 一种鹰嘴豆牙素a的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3374245A (en) * | 1964-04-01 | 1968-03-19 | Ciba Geigy Corp | Unsaturated oxacycles |
| DE1518002C3 (de) * | 1965-01-02 | 1975-01-23 | Merck Patent Gmbh, 6100 Darmstadt | Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel |
| US5280040A (en) | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US5985306A (en) * | 1996-10-28 | 1999-11-16 | Novo Nordisk A/S | (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes |
| JP2001502706A (ja) * | 1996-10-28 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | エストロゲン関連病あるいは症候群の予防または治療に有用な新規トランス―３，４クロマン誘導体 |
| KR19980064120A (ko) * | 1996-12-13 | 1998-10-07 | 김정규 | 신규한 벤조피란 유도체 |
| KR20000001793A (ko) | 1998-06-13 | 2000-01-15 | 이경하 | 신규한 벤조피란 또는 티오벤조피란 유도체 |
| IL144003A0 (en) | 1998-12-30 | 2002-04-21 | Signal Pharm Inc | Compounds and methods for modulation of estrogen receptors |
-
2002
- 2002-01-21 SI SI200230096T patent/SI1355906T1/xx unknown
- 2002-01-21 PT PT02703564T patent/PT1355906E/pt unknown
- 2002-01-21 EA EA200300727A patent/EA006158B1/ru not_active IP Right Cessation
- 2002-01-21 IL IL15706502A patent/IL157065A0/xx unknown
- 2002-01-21 DZ DZ023459A patent/DZ3459A1/fr active
- 2002-01-21 JP JP2002559415A patent/JP4332349B2/ja not_active Expired - Fee Related
- 2002-01-21 SK SK939-2003A patent/SK287086B6/sk not_active IP Right Cessation
- 2002-01-21 ES ES02703564T patent/ES2236485T3/es not_active Expired - Lifetime
- 2002-01-21 DE DE60202590T patent/DE60202590T2/de not_active Expired - Lifetime
- 2002-01-21 CN CNB02804066XA patent/CN1261431C/zh not_active Expired - Fee Related
- 2002-01-21 WO PCT/EP2002/000567 patent/WO2002059113A1/en active IP Right Grant
- 2002-01-21 MX MXPA03006505A patent/MXPA03006505A/es active IP Right Grant
- 2002-01-21 AU AU2002237282A patent/AU2002237282B2/en not_active Ceased
- 2002-01-21 EP EP02703564A patent/EP1355906B1/en not_active Expired - Lifetime
- 2002-01-21 NZ NZ527144A patent/NZ527144A/en unknown
- 2002-01-21 US US10/466,118 patent/US6951883B2/en not_active Expired - Fee Related
- 2002-01-21 BR BR0207066-9A patent/BR0207066A/pt not_active IP Right Cessation
- 2002-01-21 DK DK02703564T patent/DK1355906T3/da active
- 2002-01-21 HU HU0401018A patent/HUP0401018A3/hu unknown
- 2002-01-21 CA CA002435775A patent/CA2435775A1/en not_active Abandoned
- 2002-01-21 PL PL02365062A patent/PL365062A1/xx not_active IP Right Cessation
- 2002-01-21 AT AT02703564T patent/ATE286894T1/de not_active IP Right Cessation
- 2002-01-21 CZ CZ20032014A patent/CZ20032014A3/cs unknown
-
2003
- 2003-07-08 TN TNPCT/EP2002/000567A patent/TNSN03043A1/en unknown
- 2003-07-15 MA MA27236A patent/MA26982A1/fr unknown
- 2003-07-23 NO NO20033318A patent/NO327808B1/no not_active IP Right Cessation
- 2003-07-23 IL IL157065A patent/IL157065A/en not_active IP Right Cessation
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