SI1178799T1 - Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations - Google Patents

Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations

Info

Publication number
SI1178799T1
SI1178799T1 SI200030204T SI200030204T SI1178799T1 SI 1178799 T1 SI1178799 T1 SI 1178799T1 SI 200030204 T SI200030204 T SI 200030204T SI 200030204 T SI200030204 T SI 200030204T SI 1178799 T1 SI1178799 T1 SI 1178799T1
Authority
SI
Slovenia
Prior art keywords
pharmaceutical preparations
gastric fluid
obtaining same
microgranules
insoluble
Prior art date
Application number
SI200030204T
Other languages
English (en)
Slovenian (sl)
Inventor
Bruno Criere
Pascal Suplie
Pascal Oury
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9545866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1178799(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm filed Critical Ethypharm
Publication of SI1178799T1 publication Critical patent/SI1178799T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200030204T 1999-05-21 2000-05-19 Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations SI1178799T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9906479A FR2793688B1 (fr) 1999-05-21 1999-05-21 Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
PCT/FR2000/001367 WO2000071121A1 (fr) 1999-05-21 2000-05-19 Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
EP00929640A EP1178799B1 (fr) 1999-05-21 2000-05-19 Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
SI1178799T1 true SI1178799T1 (en) 2003-12-31

Family

ID=9545866

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030204T SI1178799T1 (en) 1999-05-21 2000-05-19 Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations

Country Status (35)

Country Link
US (1) US8409612B1 (zh)
EP (1) EP1178799B1 (zh)
JP (2) JP5344781B2 (zh)
KR (1) KR100603915B1 (zh)
CN (1) CN1243546C (zh)
AR (1) AR024036A1 (zh)
AT (1) ATE247960T1 (zh)
AU (1) AU771759B2 (zh)
BG (1) BG65415B1 (zh)
BR (1) BR0010832A (zh)
CA (1) CA2373972C (zh)
CZ (1) CZ302946B6 (zh)
DE (1) DE60004815T2 (zh)
DK (1) DK1178799T3 (zh)
EA (1) EA003943B1 (zh)
EE (1) EE04902B1 (zh)
ES (1) ES2204598T3 (zh)
FR (1) FR2793688B1 (zh)
GE (1) GEP20053580B (zh)
HK (1) HK1042851B (zh)
HR (1) HRP20010940B1 (zh)
HU (1) HU227590B1 (zh)
IL (2) IL146484A0 (zh)
IS (1) IS2160B (zh)
MX (1) MXPA01011973A (zh)
NO (1) NO331643B1 (zh)
PL (1) PL198355B1 (zh)
PT (1) PT1178799E (zh)
RS (1) RS50241B (zh)
SI (1) SI1178799T1 (zh)
SK (1) SK287605B6 (zh)
TR (1) TR200103325T2 (zh)
UA (1) UA72522C2 (zh)
WO (1) WO2000071121A1 (zh)
ZA (1) ZA200109472B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2821745B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Granules et granules enrobes au gout masque
FR2822704B1 (fr) * 2001-03-29 2005-02-18 Chiesi Sa Sels de cetoacides et d'acides amines gastroresistants et leur utilisation pour la preparation de medicaments
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
ES2924478T3 (es) 2012-03-15 2022-10-07 Boehringer Ingelheim Vetmedica Gmbh Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos
EA034430B1 (ru) 2013-07-19 2020-02-06 Бёрингер Ингельхайм Ветмедика Гмбх Жидкая водная фармацевтическая композиция с консервантами, содержащая этерифицированные производные циклодекстрина
HUE056143T2 (hu) 2013-12-04 2024-01-28 Boehringer Ingelheim Vetmedica Gmbh Pimobendán javított gyógyászati készítményei
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153677A (en) * 1978-05-18 1979-05-08 Sterling Drug Inc. Controlled-release composition
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
GB8809421D0 (en) * 1988-04-21 1988-05-25 Fordonal Sa Antacid compositions with prolonged gastric residence time
JPH0768125B2 (ja) 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
US5654009A (en) * 1991-03-25 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Delayed action preparation
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
FR2692146B1 (fr) 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
WO1995025525A1 (en) * 1994-03-18 1995-09-28 Alfred Schmidt The use of dimeticone for the local antibacterial therapy and/or the prevention and therapy of helicobacter pylori (hp) associated syndromes and infectious diseases
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
GB2290965A (en) 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
US6113941A (en) * 1994-09-30 2000-09-05 Takeda Chemical Industries, Ltd. Substained release microcapsule of physiologically active compound which is slightly water soluble at pH 6 to 8
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US5708017A (en) 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
DE69628444T2 (de) 1995-09-21 2004-05-06 Pharma Pass Ii Llc, Irvine Säurelabile omeprazol enthaltende pharmazeutische zusammensetzung und verfahren zu dessen herstellung
JPH1029937A (ja) * 1996-05-15 1998-02-03 Kobayashi Seiyaku Kogyo Kk メフェナム酸水溶液製剤
ZA979937B (en) 1996-11-06 1999-05-18 Sharmatek Inc Delayed delivery system for acid-sensitive drugs
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
ES2137862B1 (es) * 1997-07-31 2000-09-16 Intexim S A Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
DE69842173D1 (de) * 1997-12-08 2011-04-21 Nycomed Gmbh Neue Suppositoriumsform mit säureempfindlichem Wirkstoff
SE9704869D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
SE9704870D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Also Published As

Publication number Publication date
CZ20014155A3 (cs) 2002-04-17
BR0010832A (pt) 2002-03-05
NO20015480D0 (no) 2001-11-08
MXPA01011973A (es) 2002-05-06
BG65415B1 (bg) 2008-07-31
IL146484A0 (en) 2002-07-25
HK1042851B (zh) 2004-01-30
HRP20010940B1 (en) 2004-10-31
ES2204598T3 (es) 2004-05-01
DK1178799T3 (da) 2003-12-22
CN1243546C (zh) 2006-03-01
KR100603915B1 (ko) 2006-07-24
SK16322001A3 (sk) 2002-05-09
HUP0201304A3 (en) 2007-11-28
ZA200109472B (en) 2002-08-07
RS50241B (sr) 2009-07-15
AR024036A1 (es) 2002-09-04
UA72522C2 (en) 2005-03-15
CN1351494A (zh) 2002-05-29
DE60004815D1 (de) 2003-10-02
EE200100615A (et) 2003-02-17
JP2011157390A (ja) 2011-08-18
JP2003500358A (ja) 2003-01-07
HU227590B1 (hu) 2011-09-28
IS6151A (is) 2001-11-08
FR2793688B1 (fr) 2003-06-13
ATE247960T1 (de) 2003-09-15
PT1178799E (pt) 2004-01-30
TR200103325T2 (tr) 2002-05-21
NO20015480L (no) 2002-01-10
NO331643B1 (no) 2012-02-13
KR20020011990A (ko) 2002-02-09
PL198355B1 (pl) 2008-06-30
SK287605B6 (sk) 2011-03-04
JP5344781B2 (ja) 2013-11-20
EP1178799B1 (fr) 2003-08-27
IL146484A (en) 2006-04-10
EA200101221A1 (ru) 2002-04-25
US8409612B1 (en) 2013-04-02
HUP0201304A2 (en) 2002-08-28
AU771759B2 (en) 2004-04-01
CZ302946B6 (cs) 2012-01-25
HK1042851A1 (en) 2002-08-30
GEP20053580B (en) 2005-07-25
EE04902B1 (et) 2007-10-15
YU82301A (sh) 2004-07-15
CA2373972C (fr) 2011-07-12
WO2000071121A1 (fr) 2000-11-30
EA003943B1 (ru) 2003-10-30
FR2793688A1 (fr) 2000-11-24
HRP20010940A2 (en) 2003-02-28
WO2000071121A9 (fr) 2002-05-23
CA2373972A1 (fr) 2000-11-30
PL351658A1 (en) 2003-05-19
EP1178799A1 (fr) 2002-02-13
AU4765300A (en) 2000-12-12
IS2160B (is) 2006-11-15
BG106102A (en) 2002-07-31
DE60004815T2 (de) 2004-06-17

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