SI1114644T1 - Composition comprising NPH insulin (neutral protamine hagedorn insulin) - Google Patents
Composition comprising NPH insulin (neutral protamine hagedorn insulin)Info
- Publication number
- SI1114644T1 SI1114644T1 SI9730387T SI9730387T SI1114644T1 SI 1114644 T1 SI1114644 T1 SI 1114644T1 SI 9730387 T SI9730387 T SI 9730387T SI 9730387 T SI9730387 T SI 9730387T SI 1114644 T1 SI1114644 T1 SI 1114644T1
- Authority
- SI
- Slovenia
- Prior art keywords
- insulin
- composition
- nph
- neutral protamine
- protamine hagedorn
- Prior art date
Links
- 102000005237 Isophane Insulin Human genes 0.000 title 2
- 108010081368 Isophane Insulin Proteins 0.000 title 2
- LEMUFSYUPGXXCM-JNEQYSBXSA-N caninsulin Chemical compound [Zn].C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3N=CN=C3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1C=NC=N1 LEMUFSYUPGXXCM-JNEQYSBXSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/696,314 US5783556A (en) | 1996-08-13 | 1996-08-13 | Formulated insulin-containing composition |
EP01106315A EP1114644B1 (en) | 1996-08-13 | 1997-07-31 | Composition comprising NPH insulin (neutral protamine hagedorn insulin) |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1114644T1 true SI1114644T1 (en) | 2002-12-31 |
Family
ID=24796556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9730387T SI1114644T1 (en) | 1996-08-13 | 1997-07-31 | Composition comprising NPH insulin (neutral protamine hagedorn insulin) |
Country Status (16)
Country | Link |
---|---|
US (1) | US5783556A (xx) |
EP (2) | EP1114644B1 (xx) |
JP (1) | JP4187075B2 (xx) |
AR (1) | AR009066A1 (xx) |
AT (2) | ATE205722T1 (xx) |
AU (1) | AU731745B2 (xx) |
CA (1) | CA2261799C (xx) |
DE (2) | DE69714796T2 (xx) |
DK (2) | DK0918536T3 (xx) |
ES (2) | ES2180523T3 (xx) |
HK (1) | HK1042229B (xx) |
IL (1) | IL128128A (xx) |
PT (2) | PT918536E (xx) |
SI (1) | SI1114644T1 (xx) |
WO (1) | WO1998006423A1 (xx) |
ZA (1) | ZA976598B (xx) |
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DE69320919T2 (de) * | 1992-06-24 | 1999-05-12 | Hot Pepper Wax Inc., Greenville, Pa. | Organische pestizide |
ES2174852T3 (es) * | 1992-08-26 | 2002-11-16 | Celtrix Pharma | Metodo para el tratamiento sistemico de estados catabolicos y lesiones sistemicas de tejidos. |
EP0642350A4 (en) * | 1993-01-25 | 1995-06-28 | Beth Israel Hospital | PROCESS FOR MODIFICATION, DIAGNOSIS AND SCREENING OF IGF-I SENSITIVE CELL BARRIER CHARACTERISTICS. |
JPH09500088A (ja) * | 1993-01-29 | 1997-01-07 | アムジェン ボールダー インコーポレイテッド | 創傷治癒用組成物 |
SE9402119D0 (sv) * | 1994-06-16 | 1994-06-16 | Pharmacia Ab | Solution |
SE9402331D0 (sv) * | 1994-07-01 | 1994-07-01 | Pharmacia Ab | New use |
SE9402370D0 (sv) * | 1994-07-04 | 1994-07-04 | Pharmacia Ab | Use of IGF-I |
AUPM678294A0 (en) * | 1994-07-13 | 1994-08-04 | Gropep Pty Ltd | Use of insulin-like growth factor in combination with insulin |
DK1044015T3 (da) * | 1998-01-09 | 2008-12-08 | Amylin Pharmaceuticals Inc | Formuleringer med amylinagonistpeptider og insulin |
KR100617286B1 (ko) * | 1998-10-16 | 2006-08-30 | 노보 노르디스크 에이/에스 | 폐 송달을 위한 안정한 농축 인슐린 조제물 |
IL145597A0 (en) * | 1999-04-08 | 2002-06-30 | Genentech Inc | Composition based on oppositely-charged polypeptides |
CA2369839A1 (en) * | 1999-06-25 | 2001-01-04 | Minimed, Inc. | Compositions of insulin and insulin-related peptide for treating diabetes |
-
1996
- 1996-08-13 US US08/696,314 patent/US5783556A/en not_active Expired - Lifetime
-
1997
- 1997-07-24 ZA ZA976598A patent/ZA976598B/xx unknown
- 1997-07-31 AT AT97935259T patent/ATE205722T1/de active
- 1997-07-31 JP JP50979998A patent/JP4187075B2/ja not_active Expired - Lifetime
- 1997-07-31 PT PT97935259T patent/PT918536E/pt unknown
- 1997-07-31 ES ES01106315T patent/ES2180523T3/es not_active Expired - Lifetime
- 1997-07-31 ES ES97935259T patent/ES2162321T3/es not_active Expired - Lifetime
- 1997-07-31 AU AU38243/97A patent/AU731745B2/en not_active Expired
- 1997-07-31 SI SI9730387T patent/SI1114644T1/xx unknown
- 1997-07-31 IL IL128128A patent/IL128128A/en not_active IP Right Cessation
- 1997-07-31 DK DK97935259T patent/DK0918536T3/da active
- 1997-07-31 WO PCT/US1997/013566 patent/WO1998006423A1/en active IP Right Grant
- 1997-07-31 CA CA002261799A patent/CA2261799C/en not_active Expired - Lifetime
- 1997-07-31 AT AT01106315T patent/ATE222120T1/de active
- 1997-07-31 DK DK01106315T patent/DK1114644T3/da active
- 1997-07-31 DE DE69714796T patent/DE69714796T2/de not_active Expired - Lifetime
- 1997-07-31 EP EP01106315A patent/EP1114644B1/en not_active Expired - Lifetime
- 1997-07-31 DE DE69706872T patent/DE69706872T2/de not_active Expired - Lifetime
- 1997-07-31 EP EP97935259A patent/EP0918536B1/en not_active Expired - Lifetime
- 1997-07-31 PT PT01106315T patent/PT1114644E/pt unknown
- 1997-08-12 AR ARP970103667A patent/AR009066A1/es active IP Right Grant
-
2002
- 2002-01-10 HK HK02100191.5A patent/HK1042229B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69706872D1 (de) | 2001-10-25 |
EP0918536A1 (en) | 1999-06-02 |
EP1114644B1 (en) | 2002-08-14 |
CA2261799C (en) | 2009-09-08 |
DE69714796D1 (de) | 2002-09-19 |
US5783556A (en) | 1998-07-21 |
IL128128A (en) | 2007-06-17 |
WO1998006423A1 (en) | 1998-02-19 |
ES2180523T3 (es) | 2003-02-16 |
JP4187075B2 (ja) | 2008-11-26 |
DE69714796T2 (de) | 2003-04-03 |
EP1114644A1 (en) | 2001-07-11 |
HK1042229A1 (en) | 2002-08-09 |
HK1042229B (zh) | 2003-08-15 |
AU3824397A (en) | 1998-03-06 |
IL128128A0 (en) | 1999-11-30 |
PT1114644E (pt) | 2002-12-31 |
DK0918536T3 (da) | 2001-12-03 |
AR009066A1 (es) | 2000-03-08 |
DE69706872T2 (de) | 2002-04-25 |
AU731745B2 (en) | 2001-04-05 |
ES2162321T3 (es) | 2001-12-16 |
PT918536E (pt) | 2002-03-28 |
ATE205722T1 (de) | 2001-10-15 |
JP2000516229A (ja) | 2000-12-05 |
EP0918536B1 (en) | 2001-09-19 |
DK1114644T3 (da) | 2002-11-04 |
ATE222120T1 (de) | 2002-08-15 |
CA2261799A1 (en) | 1998-02-19 |
ZA976598B (en) | 1999-02-17 |
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