SI1042316T1 - - Google Patents

Info

Publication number
SI1042316T1
SI1042316T1 SI9830765T SI9830765T SI1042316T1 SI 1042316 T1 SI1042316 T1 SI 1042316T1 SI 9830765 T SI9830765 T SI 9830765T SI 9830765 T SI9830765 T SI 9830765T SI 1042316 T1 SI1042316 T1 SI 1042316T1
Authority
SI
Slovenia
Application number
SI9830765T
Inventor
Stefania Gagliardi
Guy Marguerite Marie Ge Nadler
Pietro Novella
Original Assignee
Nikem Research Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikem Research Srl filed Critical Nikem Research Srl
Publication of SI1042316T1 publication Critical patent/SI1042316T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI9830765T 1997-12-24 1998-12-17 SI1042316T1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97403154 1997-12-24
PCT/EP1998/008561 WO1999033822A1 (en) 1997-12-24 1998-12-17 Indole derivatives useful a.o. for the treatment of osteoporosis
EP98966951A EP1042316B1 (en) 1997-12-24 1998-12-17 Indole derivatives useful a.o. for the treatment of osteoporosis

Publications (1)

Publication Number Publication Date
SI1042316T1 true SI1042316T1 (ja) 2005-08-31

Family

ID=8229937

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830765T SI1042316T1 (ja) 1997-12-24 1998-12-17

Country Status (23)

Country Link
EP (1) EP1042316B1 (ja)
JP (1) JP4627881B2 (ja)
KR (1) KR20010033528A (ja)
CN (1) CN1208333C (ja)
AR (1) AR018032A1 (ja)
AT (1) ATE288909T1 (ja)
AU (1) AU749319B2 (ja)
BR (1) BR9814403A (ja)
CA (1) CA2315723A1 (ja)
CO (1) CO4970811A1 (ja)
DE (1) DE69828998T2 (ja)
ES (1) ES2236971T3 (ja)
HK (1) HK1032953A1 (ja)
HU (1) HUP0100785A3 (ja)
IL (1) IL136720A0 (ja)
NO (1) NO320272B1 (ja)
NZ (1) NZ505060A (ja)
PL (1) PL191633B1 (ja)
SA (1) SA99200109B1 (ja)
SI (1) SI1042316T1 (ja)
TR (1) TR200001992T2 (ja)
WO (1) WO1999033822A1 (ja)
ZA (1) ZA9811758B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9914371D0 (en) 1999-06-18 1999-08-18 Smithkline Beecham Plc Novel compounds
GB9914825D0 (en) 1999-06-24 1999-08-25 Smithkline Beecham Spa Novel compounds
DE60128211T2 (de) 2000-03-31 2008-01-10 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituierte imidazopyridine
EP1268421B1 (en) * 2000-03-31 2009-05-06 Ortho-McNeil Pharmaceutical, Inc. Phenyl-substituted indoles as histamine h3-receptor antagonists
US6872834B2 (en) 2000-03-31 2005-03-29 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituted indoles and indazoles
ITMI20040875A1 (it) * 2004-04-30 2004-07-30 Ist Naz Stud Cura Dei Tumori Derivati indolici utili per il trattamento della resistenza agli agenti antitumorali
US20090142832A1 (en) * 2007-11-29 2009-06-04 James Dalton Indoles, Derivatives, and Analogs Thereof and Uses Therefor
AR072297A1 (es) 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
KR102134171B1 (ko) * 2014-10-24 2020-07-15 란도스 바이오파마, 인크. 란티오닌 합성효소 c-유사 2-계 치료제
WO2019108418A1 (en) 2017-11-30 2019-06-06 Landos Biopharma, Inc. Therapies with lanthionine c-like protein 2 ligands and cells prepared therewith
KR20230026522A (ko) 2019-12-20 2023-02-24 란도스 바이오파마, 인크. 란티오닌 c-유사 단백질 2 리간드, 이로 제조된 세포, 및 이를 사용하는 치료법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3542827B2 (ja) * 1994-07-15 2004-07-14 帝国臓器製薬株式会社 新規な５−置換イソキサゾール−３−カルボン酸アミド誘導体
TR199700625T1 (xx) * 1995-01-10 1998-02-21 Smithkline Beecham S.P.A. Osteoporoz (kemik erimesi) tedavisinde yararl� olan indol t�revleri.
EP0991623A2 (en) * 1997-06-19 2000-04-12 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en) * 1997-06-19 2001-03-27 Sepracor, Inc. Antimicrobial agents uses and compositions related thereto

Also Published As

Publication number Publication date
CA2315723A1 (en) 1999-07-08
DE69828998D1 (de) 2005-03-17
CN1208333C (zh) 2005-06-29
ES2236971T3 (es) 2005-07-16
DE69828998T2 (de) 2006-05-04
SA99200109B1 (ar) 2006-09-13
NZ505060A (en) 2002-09-27
AU2715499A (en) 1999-07-19
ATE288909T1 (de) 2005-02-15
AU749319B2 (en) 2002-06-20
NO320272B1 (no) 2005-11-14
HUP0100785A2 (hu) 2001-08-28
TR200001992T2 (tr) 2001-01-22
ZA9811758B (en) 2000-06-22
IL136720A0 (en) 2001-06-14
PL191633B1 (pl) 2006-06-30
AR018032A1 (es) 2001-10-31
BR9814403A (pt) 2000-10-10
HK1032953A1 (en) 2001-08-10
CN1299357A (zh) 2001-06-13
NO20003315L (no) 2000-06-23
EP1042316A1 (en) 2000-10-11
JP2003532616A (ja) 2003-11-05
JP4627881B2 (ja) 2011-02-09
EP1042316B1 (en) 2005-02-09
HUP0100785A3 (en) 2001-09-28
WO1999033822A1 (en) 1999-07-08
NO20003315D0 (no) 2000-06-23
CO4970811A1 (es) 2000-11-07
PL341318A1 (en) 2001-04-09
KR20010033528A (ko) 2001-04-25

Similar Documents

Publication Publication Date Title
CH0944937H2 (ja)
ITMI971227A0 (ja)
BR9700653A (ja)
BR9701757A (ja)
ITRM970120V0 (ja)
ITMI971518A0 (ja)
CN3056417S (ja)
CN3056811S (ja)
CN3053500S (ja)
CN3053525S (ja)
CN3054099S (ja)
CN3054162S (ja)
BY4349C1 (ja)
CN3054902S (ja)
BY4238C1 (ja)
CN3055179S (ja)
CN3055389S (ja)
CN3055471S (ja)
CN3055519S (ja)
CN3055603S (ja)
CN3055713S (ja)
CN3056209S (ja)
CN3056251S (ja)
CN3056276S (ja)
CN3055123S (ja)